Factors associated with steatosis in patients with chronic hepatitis C

2000 ◽  
Vol 95 (9) ◽  
pp. 2517-2517
Author(s):  
Petrea Monson ◽  
Deanna L. Oliver ◽  
Annette Pohl ◽  
Cynthia Behling ◽  
Nina Aronson ◽  
...  
2011 ◽  
Vol 48 (3) ◽  
pp. 179-185
Author(s):  
Leonora De Zorzi Piccoli ◽  
Angelo Alves de Mattos ◽  
Gabriela Perdomo Coral ◽  
Ângelo Zambam de Mattos ◽  
Diogo Edele dos Santos

CONTEXT: Chronic hepatitis C as well as non-alcoholic fatty liver disease are recognized as the main cause of liver disease in Western countries. It is common to see the concomitance of the diseases and the influence of steatosis in the sustained virological response of patients with hepatitis C virus. OBJECTIVE: Assess the sustained virological response in chronic hepatitis C patients according to the presence of liver steatosis. METHODS: One hundred sixty patients with chronic hepatitis C were retrospectively evaluated. Demographic data such as gender, age, body mass index, presence of diabetes mellitus and systemic arterial hypertension, virus genotype and use of pegylated interferon were analyzed, as was the staging of fibrosis and the presence of steatosis at histology. RESULTS: Most patients were male (57.5%), with a mean age of 48 ± 9.7 years. The most frequent genotype observed was 3 (56.9%) and, in the histological evaluation, steatosis was observed in 65% of the patients (104/160). Sustained virological response in patients with steatosis occurred in 38.5%, and in 32.1% in patients without steatosis (P = 0.54). When we analyzed possible factors associated with the presence of steatosis, only body mass index and systemic arterial hypertension revealed a significant association. When the factors that influenced sustained virological response were evaluated in a logistic regression, genotype and use of pegylated interferon proved to be independent factors associated to the response. CONCLUSION: In the evaluated patients the presence of liver steatosis did not influence the sustained virological response of patients with chronic hepatitis C treated with interferon and ribavirin.


2006 ◽  
Vol 101 ◽  
pp. S166-S167
Author(s):  
Mohammad Minakari ◽  
Mohammadreza Zali ◽  
Farzaneh Khademsameni ◽  
Hamid Mohagheghshalmani

2016 ◽  
Vol 65 (2) ◽  
pp. 266-272 ◽  
Author(s):  
Naomi Bulteel ◽  
Prasanna Partha Sarathy ◽  
Ewan Forrest ◽  
Adrian J. Stanley ◽  
Hamish Innes ◽  
...  

2009 ◽  
Vol 30 (3) ◽  
pp. 285-299 ◽  
Author(s):  
Janet E Forrester ◽  
Xiang D Wang ◽  
Tamsin A Knox ◽  
Carmia G Borek ◽  
Alice M Tang ◽  
...  

2011 ◽  
Vol 7 (2) ◽  
pp. 508-515 ◽  
Author(s):  
Shunsuke Sato ◽  
Takuya Genda ◽  
Katsuharu Hirano ◽  
Hironori Tsuzura ◽  
Yoshio Kanemitsu ◽  
...  

2017 ◽  
Vol 62 (8) ◽  
pp. 2159-2165 ◽  
Author(s):  
Ali Afsari ◽  
Edward Lee ◽  
Babak Shokrani ◽  
Tina Boortalary ◽  
Zaki A. Sherif ◽  
...  

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