The in vitro adhesion of Candida albicans to buccal epithelial cells (BEC) from diabetic and non-diabetic individuals after in vivo and in vitro application of nystatin

1997 ◽  
Vol 26 (5) ◽  
pp. 233-236 ◽  
Author(s):  
A. M. G. Darwazeh ◽  
T. W. MacFarlane ◽  
P.-J. Lamey
1990 ◽  
Vol 33 (1) ◽  
pp. 43-49 ◽  
Author(s):  
A. M. G. DARWAZEH ◽  
P.-J. LAMEY ◽  
L. P. SAMARANAYAKE ◽  
T. W. MACFARLANE ◽  
B. M. FISHER ◽  
...  

1984 ◽  
Vol 30 (3) ◽  
pp. 381-388 ◽  
Author(s):  
B. R. Merrell ◽  
R. I. Walker ◽  
S. W. Joseph

The initial interaction and adherence of Vibrio parahemolyticus to epithelial tissue culture cells, human buccal epithelial cells, and the ileal mucosa of mice were studied. Using scanning electron microscopy, adherent bacteria were observed only on degenerating human embryonic intestinal, HeLa, and buccal cells; healthy normal cells were devoid of bacteria. Sheared V. parahaemolyticus, i.e., lacking flagella, did not adhere to either normal or degenerating tissue cells. Neither ultraviolet-inactivated organisms nor cell-free culture supernate affected the epithelial cells. Similar findings were observed on the mucosa of the ileum in mice inoculated with V. parahaemolyticus. It appears that V. parahaemolyticus possesses a cytotoxic factor which alters epithelial cells. This factor appears to be closely associated with viable organisms and may be a functional element in the adherence process of flagellated V. parahaemolyticus to mammalian epithelial cells.


2015 ◽  
Vol 60 (3) ◽  
pp. 471-478 ◽  
Author(s):  
Ermelinda Matsuura ◽  
Janine Silva Ribeiro Godoy ◽  
Patrícia de Souza Bonfim-Mendonça ◽  
João Carlos Palazzo de Mello ◽  
Terezinha Inez Estivalet Svidzinski ◽  
...  

2005 ◽  
Vol 96 (1-2) ◽  
pp. 221-226 ◽  
Author(s):  
S. Taweechaisupapong ◽  
T. Choopan ◽  
S. Singhara ◽  
S. Chatrchaiwiwatana ◽  
S. Wongkham

2001 ◽  
Vol 69 (12) ◽  
pp. 7898-7903 ◽  
Author(s):  
Praveen Singh ◽  
Sharmistha Ghosh ◽  
Asis Datta

ABSTRACT A Candida albicans mutant with mutations in theN-acetylglucosamine (GlcNAc) catabolic pathway gene cluster, including the GlcNAc-6-phosphate deacetylase (DAC1), glucosamine-6-phosphate deaminase (NAG1), and GlcNAc kinase (HXK1) genes, was not able to grow on amino sugars, exhibited highly attenuated virulence in a murine systemic candidiasis model, and was less adherent to human buccal epithelial cells in vitro. No germ tubes were formed by the mutant after induction with GlcNAc, but the mutant exhibited hyperfilamentation under stress-induced filamentation conditions. In addition, the GlcNAc catabolic pathway played a vital role in determining the colony phenotype. Our results imply that this pathway is very important because of its diverse links with pathways involved in virulence and morphogenesis of the organism.


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