Luteinizing hormone-releasing hormone and innervation pathways in human prenatal nasal submucosa: factors of importance in evaluating Kallmann's syndrome

Apmis ◽  
1996 ◽  
Vol 104 (7-8) ◽  
pp. 680-688 ◽  
Author(s):  
Inger KjaeR ◽  
Birgit Fischer Hansen
Keyword(s):  
Luteinizing Hormone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Kallmann's Syndrome ◽  
Kallmann’S Syndrome

Consecutive administration of synthetic LRH in the evaluation of gonadotrophin reserve in children

1980 ◽  
Vol 94 (3) ◽  
pp. 289-296 ◽  
Author(s):  
Masako Tomita
Keyword(s):  
Anorexia Nervosa ◽  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Primary Lesion ◽  
Luteinizing Hormone Releasing Hormone ◽  
Pituitary Dwarfism ◽  
Releasing Hormone ◽  
Initial Injection ◽  
Kallmann's Syndrome ◽  
Kallmann’S Syndrome

Abstract. Initial injection of synthetic luteinizing hormone releasing hormone (LRH) into 40 children elicited no response in LH and follicle stimulating hormone (FSH) in 15 patients with pituitary dwarfism, one with Kallmann's syndrome and in 3 anorexia nervosa patients. These patients were further treated with LRH for periods of either 3 or 14 days and the second LRH test showed an increase in LH and/or FSH in 67% of the patients with pituitary dwarfism, in the Kallmann's syndrome and in all of the anorexia nervosa patients. This result suggested that while pituitary gonadotrophs did not respond at the first LRH test because of the chronic absence of stimulation, consecutive LRH therapy, however, restored the ability to secrete LH and FSH and indicated that the pituitary was not the site of the primary lesion in these patients. The LRH test following consecutive administration of LRH may be valuable in determining whether the lesion is located in the hypothalamus or the pituitary.

EFFECT OF CORTISOL OR ADRENOCORTICOTROPHIN ON RELEASE OF LUTEINIZING HORMONE INDUCED BY LUTEINIZING HORMONE RELEASING HORMONE IN THE DAIRY HEIFER

1982 ◽  
Vol 92 (1) ◽  
pp. 141-146 ◽  
Author(s):  
R. L. MATTERI ◽  
G. P. MOBERG
Keyword(s):  
Luteinizing Hormone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Dairy Heifers ◽  
Significant Difference ◽  
Significant Depression ◽  
Lh Rh ◽  
Lh Releasing Hormone ◽  
And Control ◽  
Slight Depression

During treatment with cortisol or ACTH, dairy heifers were given two doses of LH releasing hormone (LH-RH) spaced 1·5 h apart. Serum concentrations of cortisol and LH were monitored during each treatment. Treatment with both ACTH and cortisol raised plasma cortisol levels above the respective saline controls (P<0·001). Neither treatment affected basal LH concentrations. A slight depression in LH response was seen in the cortisol-treated animals after the first LH-RH injection, as shown by a statistically significant depression at three of the sample times. There was no significant difference between treated and control LH values after the second LH-RH administration. Treatment with ACTH resulted in significantly reduced LH values at all sample times after both injections of LH-RH.

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