Effects of Flapless Implant Surgery on Soft Tissue Profiles: A Prospective Clinical Study

2009 ◽  
Vol 13 (4) ◽  
pp. 324-329 ◽  
Author(s):  
Du-Hyeong Lee ◽  
Byung-Ho Choi ◽  
Seung-Mi Jeong ◽  
Feng Xuan ◽  
Ha-Rang Kim
Keyword(s):  
Clinical Study ◽  
Soft Tissue ◽  
Prospective Clinical Study ◽  
Implant Surgery

Is there a learning curve in static computer-assisted implant surgery? A prospective clinical study

2020 ◽  
Vol 49 (10) ◽  
pp. 1335-1342 ◽  
Author(s):  
M. Cassetta ◽  
F. Altieri ◽  
M. Giansanti ◽  
M. Bellardini ◽  
G. Brandetti ◽  
...  
Keyword(s):  
Clinical Study ◽  
Learning Curve ◽  
Prospective Clinical Study ◽  
Computer Assisted ◽  
Implant Surgery

Topical dimethylsulfoxide for the prevention of soft tissue injury after extravasation of vesicant cytotoxic drugs: a prospective clinical study.

1995 ◽  
Vol 13 (11) ◽  
pp. 2851-2855 ◽  
Author(s):  
G Bertelli ◽  
A Gozza ◽  
G B Forno ◽  
M G Vidili ◽  
S Silvestro ◽  
...  
Keyword(s):  
Clinical Study ◽  
Soft Tissue ◽  
Tissue Injury ◽  
Soft Tissue Injury ◽  
Preventive Treatment ◽  
Cytotoxic Drugs ◽  
Prospective Clinical Study ◽  
Local Cooling ◽  
Open Prospective Study ◽  
Local Burning

PURPOSE To evaluate the activity and tolerability of dimethylsulfoxide (DMSO) in the prevention of soft tissue toxicity after extravasation of cytotoxic drugs. PATIENTS AND METHODS From June 1991 to December 1994, all patients who had an extravasation during intravenous (IV) infusion of cytotoxic drugs in our institution were considered for an open, prospective study of preventive treatment with 99% DMSO, applied topically on the extravasation site every 8 hours for 7 days. Intermittent local cooling (for 1 hour three times daily) on the first 3 days was also used. RESULTS One hundred forty-four patients with extravasations of doxorubicin (n = 11), epirubicin (n = 46), mitomycin (n = 5), mitoxantrone (n = 13), cisplatin (n = 44), carboplatin (n = 6), ifosfamide (n = 14), and fluorouracil (n = 5) entered the study; 127 were assessable. Only one patient suffered an ulceration. The treatment was well tolerated, with mild local burning and a characteristic breath odor being the only side effects of DMSO application, even in cases in which treatment continued for up to 6 weeks to obtain remission of the symptoms of extravasation. CONCLUSION Topical DMSO is an effective and safe antidote that may be used with local cooling after extravasations of vesicant drugs other than those drugs for which standard interventions are defined.

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