Changes in the Concentration and Fatty Acid Composition of Phospholipids in Rat Skeletal Muscle during Postnatal Development

1974 ◽  
Vol 90 (4) ◽  
pp. 743-749 ◽  
Author(s):  
Åke Bruce
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Postnatal Development ◽  
Acid Composition ◽  
Rat Skeletal Muscle

scholarly journals Membrane fatty acid composition of rat skeletal muscle is most responsive to the balance of dietary n-3 and n-6 PUFA

2009 ◽  
Vol 103 (4) ◽  
pp. 522-529 ◽  
Author(s):  
Sarah K. Abbott ◽  
Paul L. Else ◽  
A. J. Hulbert
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Acid Composition ◽  
Essential Fatty Acids ◽  
Muscle Membrane ◽  
Rat Skeletal Muscle ◽  
Muscle Composition

The present study quantifies the relationships between diet fatty acid profile and fatty acid composition of rat skeletal muscle phospholipids. Young adult male Sprague–Dawley rats were fed, for 8 weeks, on one of twelve moderate-fat diets (25 % of total energy) differing only in fatty acid profile. SFA content ranged from 8–88 % of total fatty acids, MUFA 6–65 %, total PUFA 4–81 %, n-6 PUFA 3–70 % and n-3 PUFA 1–70 %. Diet PUFA included only essential fatty acids 18 : 2n-6 and 18 : 3n-3. The balance between n-3 and n-6 PUFA (PUFA balance) in the diet ranged from 1 : 99 to 86 : 14 % n-3 PUFA:n-6 PUFA. The slope of muscle phospholipid composition plotted against diet composition quantifies the response of muscle membrane composition to dietary fat (0, no response; 1, complete conformity with diet). The resulting slopes were 0·02 (SFA), 0·10 (PUFA), 0·11 (MUFA), 0·14 (n-3 PUFA) and 0·23 (n-6 PUFA). The response to PUFA balance was biphasic with a slope of 0·98 below 10 % diet PUFA balance and 0·16 above 10 %. Thus, low diet PUFA balance has greater influence on muscle composition than 18-carbon n-3 or n-6 PUFA individually. Equations provided may allow prediction of muscle composition for other diet studies. Diet PUFA balance dramatically affects muscle 20 : 4n-6 and 22 : 6n-3. This may have significant implications for some disease states in human subjects.

Sarcoplasmic Reticulum Phospholipid Fatty Acid Composition and Sarcolipin Content in Rat Skeletal Muscle

2015 ◽  
Vol 248 (6) ◽  
pp. 1089-1096 ◽  
Author(s):  
Val Andrew Fajardo ◽  
Eric Bombardier ◽  
Khanh Tran ◽  
Adam H. Metherel ◽  
Thomas Irvine ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Sarcoplasmic Reticulum ◽  
Acid Composition ◽  
Phospholipid Fatty Acid ◽  
Phospholipid Fatty Acid Composition ◽  
Rat Skeletal Muscle

Fatty acid profile of skeletal muscle phospholipids in trained and untrained young men

2000 ◽  
Vol 279 (4) ◽  
pp. E744-E751 ◽  
Author(s):  
Agneta Andersson ◽  
Anders Sjödin ◽  
Anu Hedman ◽  
Roger Olsson ◽  
Bengt Vessby
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Acid Composition ◽  
Fiber Type ◽  
Young Men ◽  
Trained Group ◽  
Type Distribution ◽  
Fiber Type Distribution

Endurance trained ( n = 14) and untrained young men ( n = 15) were compared regarding the fatty acid profile of the vastus lateralis muscle after 8 wk on diets with a similar fatty acid composition. The skeletal muscle phospholipids in the trained group contained lower proportions of palmitic acid (16:0) (−12.4%, P < 0.001) and di-homo-γ-linolenic acid [20:3(n-6)] (−15.3%, P = 0.018), a lower n-6-to-n-3 ratio (−42.0%, P = 0.015), higher proportions of stearic acid (18:0) (+9.8%, P = 0.004) and sum of n-3 polyunsaturated fatty acids (+33.8%, P = 0.009), and a higher ratio between 20:4(n-6) to 20:3(n-6) (+18.4%, P = 0.006) compared with those in the untrained group. The group differences in 16:0, 20:3(n-6), 18:0/16:0, and 20:4(n-6)/20:3(n-6) were independent of fiber-type distribution. The trained group also showed a lower proportion of 16:0 (−7.9%, P < 0.001) in skeletal muscle triglycerides irrespective of fiber type. In conclusion, the fatty acid profile of the skeletal muscle differed between trained and untrained individuals, although the dietary fatty acid composition was similar. This difference was not explained by different fiber-type distribution alone but appears to be a direct consequence of changes in fatty acid metabolism due to the higher level of physical activity.

scholarly journals Fatty acid composition of skeletal muscle reflects dietary fat composition in humans

2002 ◽  
Vol 76 (6) ◽  
pp. 1222-1229 ◽  
Author(s):  
Agneta Andersson ◽  
Cecilia Nälsén ◽  
Siv Tengblad ◽  
Bengt Vessby
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Dietary Fat ◽  
Fat Composition

Improved Insulin Sensitivity by Bezafibrate in Rats: Relationship to Fatty Acid Composition of Skeletal-Muscle Triglycerides

Diabetes ◽  
1997 ◽  
Vol 46 (3) ◽  
pp. 348-353 ◽  
Author(s):  
H. Matsui ◽  
K. Okumura ◽  
K. Kawakami ◽  
M. Hibino ◽  
Y. Toki ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Insulin Sensitivity ◽  
Acid Composition
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