Pituitary Adenylate Cyclase-Activating Polypeptide Induces Gene Expression of the Catecholamine Synthesizing Enzymes, Tyrosine Hydroxylase, and Dopamine beta-Hydroxylase in Cultured Porcine Adrenal Medullary Chromaffin Cells

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1996.tb17504.x ◽

2006 ◽

Vol 805 (1) ◽

pp. 464-469 ◽

Author(s):

KAZUMASA ISOBE ◽

NOBUYASU YUKIMASA ◽

TOSHIAKI NAKAI ◽

YOH TAKUWA

Keyword(s):

Gene Expression ◽

Tyrosine Hydroxylase ◽

Adenylate Cyclase ◽

Chromaffin Cells ◽

Dopamine Beta Hydroxylase ◽

Pituitary Adenylate Cyclase ◽

Catecholamine Synthesizing Enzymes

Download Full-text

Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine β hydroxylase, through 3′, 5′-cyclic adenosine monophosphate- and protein kinase C-dependent mechanisms in cultured porcine adrenal medullary chromaffin cells

Neuropeptides ◽

10.1016/s0143-4179(96)90084-0 ◽

1996 ◽

Vol 30 (2) ◽

pp. 167-175 ◽

Author(s):

K Isobe ◽

N Yukimasa ◽

T Nakai ◽

Y Takuwa

Keyword(s):

Gene Expression ◽

Protein Kinase C ◽

Tyrosine Hydroxylase ◽

Protein Kinase ◽

Chromaffin Cells ◽

Cyclic Adenosine Monophosphate ◽

Adenosine Monophosphate ◽

Kinase C ◽

Pituitary Adenylate Cyclase ◽

Catecholamine Synthesizing Enzymes

Download Full-text

Stimulatory Effect of Pituitary Adenylate Cyclase-Activating Polypeptide on Catecholamine Synthesis in Cultured Bovine Adrenal Chromaffin Cells: Involvements of Tyrosine Hydroxylase Phosphorylation Caused by Ca2+ Influx and cAMP

The Japanese Journal of Pharmacology ◽

10.1254/jjp.66.323 ◽

1994 ◽

Vol 66 (3) ◽

pp. 323-330 ◽

Author(s):

Hitoshi Houchi ◽

Shuichi Hamano ◽

Yutaka Masuda ◽

Yasuko Ishimura ◽

Mami Azuma ◽

...

Keyword(s):

Tyrosine Hydroxylase ◽

Adenylate Cyclase ◽

Chromaffin Cells ◽

Adrenal Chromaffin Cells ◽

Catecholamine Synthesis ◽

Pituitary Adenylate Cyclase ◽

Adrenal Chromaffin ◽

Tyrosine Hydroxylase Phosphorylation

Download Full-text

Effect of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) on Tyrosine Hydroxylase Gene Expression in the Rat Adrenal Medulla

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1998.tb11220.x ◽

1998 ◽

Vol 865 (1 VIP, PACAP, A) ◽

pp. 478-481 ◽

Author(s):

M. HONG ◽

L. YON ◽

A. FOURNIER ◽

H. VAUDRY ◽

G. PELLETIER

Keyword(s):

Gene Expression ◽

Tyrosine Hydroxylase ◽

Adenylate Cyclase ◽

Adrenal Medulla ◽

Tyrosine Hydroxylase Gene ◽

Hydroxylase Gene ◽

Pituitary Adenylate Cyclase

Download Full-text

Transcriptional and Posttranscriptional Control of Tyrosine Hydroxylase Gene Expression During Persistent Stimulation of Pituitary Adenylate Cyclase-Activating Polypeptide Receptors on PC12 Cells: Regulation by Protein Kinase A-Dependent and Protein Kinas

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1998.71020478.x ◽

2002 ◽

Vol 71 (2) ◽

pp. 478-486 ◽

Author(s):

James Corbitt ◽

Jeevalatha Vivekananda ◽

Shou Shu Wang ◽

Randy Strong

Keyword(s):

Gene Expression ◽

Tyrosine Hydroxylase ◽

Protein Kinase ◽

Adenylate Cyclase ◽

Protein Kinase A ◽

Posttranscriptional Control ◽

Pituitary Adenylate Cyclase ◽

Kinase A ◽

Download Full-text

Activation of tyrosine hydroxylase by pituitary adenylate cyclase-activating polypeptide (PACAP-27) in bovine adrenal chromaffin cells

Journal of the Autonomic Nervous System ◽

10.1016/0165-1838(96)00044-6 ◽

1996 ◽

Vol 60 (3) ◽

pp. 141-146 ◽

Author(s):

Philip D. Marley ◽

Cecilia Y. Cheung ◽

Kerrie A. Thomson ◽

Roger Murphy

Keyword(s):

Tyrosine Hydroxylase ◽

Adenylate Cyclase ◽

Chromaffin Cells ◽

Adrenal Chromaffin Cells ◽

Pituitary Adenylate Cyclase ◽

Adrenal Chromaffin

Download Full-text

Pituitary adenylate cyclase activating polypeptide (PACAP) potently enhances tyrosine hydroxylase (TH) expression in adrenal chromaffin cells

Life Sciences ◽

10.1016/0024-3205(94)00614-8 ◽

1994 ◽

Vol 54 (22) ◽

pp. 1735-1743 ◽

Author(s):

Ricardo Adrian Rius ◽

Alessandro Guidotti ◽

Erminio Costa

Keyword(s):

Tyrosine Hydroxylase ◽

Adenylate Cyclase ◽

Chromaffin Cells ◽

Adrenal Chromaffin Cells ◽

Pituitary Adenylate Cyclase ◽

Adrenal Chromaffin

Download Full-text

Pituitary adenylate cyclase-activating polypeptide stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway

Neuroscience ◽

10.1016/s0306-4522(97)00545-9 ◽

1998 ◽

Vol 84 (3) ◽

pp. 801-812 ◽

Author(s):

D Vaudry ◽

B.J Gonzalez ◽

M Basille ◽

Y Anouar ◽

A Fournier ◽

...

Keyword(s):

Gene Expression ◽

Protein Kinase ◽

Adenylate Cyclase ◽

Cell Survival ◽

Protein Kinase A ◽

Cerebellar Granule Neurons ◽

Granule Neurons ◽

Cerebellar Granule ◽

Pituitary Adenylate Cyclase ◽

Download Full-text

Pituitary Adenylate Cyclase Activating Polypeptide and Neuropeptide Y Regulation of Gonadotropin Subunit Gene Expression in Tilapia: Role of PKC, PKA and ERK

Neuroendocrinology ◽

10.1159/000048234 ◽

2002 ◽

Vol 75 (3) ◽

pp. 164-174 ◽

Author(s):

Gal Gur ◽

David Bonfil ◽

Helena Safarian ◽

Zvi Naor ◽

Zvi Yaron

Keyword(s):

Gene Expression ◽

Adenylate Cyclase ◽

Neuropeptide Y ◽

Subunit Gene ◽

Pituitary Adenylate Cyclase

Download Full-text

Enhanced cAMP production mediates the stimulatory action of pituitary adenylate cyclase activating polypeptide (PACAP) on in vitro catecholamine secretion from bovine adrenal chromaffin cells

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-0029-1211333 ◽

2009 ◽

Vol 103 (02) ◽

pp. 81-87 ◽

Author(s):

D. Perrin ◽

A. Germeshausen ◽

H.-D. Söling ◽

W. Wuttke ◽

H. Jarry

Keyword(s):

Adenylate Cyclase ◽

Chromaffin Cells ◽

Catecholamine Secretion ◽

Adrenal Chromaffin Cells ◽

Camp Production ◽

Stimulatory Action ◽

Pituitary Adenylate Cyclase ◽

Adrenal Chromaffin

Download Full-text

Cellular localization of tyrosine hydroxylase by immunohistochemistry.

Journal of Histochemistry & Cytochemistry ◽

10.1177/23.1.234988 ◽

1975 ◽

Vol 23 (1) ◽

pp. 1-12 ◽

Author(s):

V M Pickel ◽

T H Joh ◽

P M Field ◽

C G Becker ◽

D J Reis

Keyword(s):

Tyrosine Hydroxylase ◽

Dopaminergic Neurons ◽

Chromaffin Cells ◽

Cellular Localization ◽

Dopaminergic System ◽

Noradrenergic Neurons ◽

Dopamine Beta Hydroxylase ◽

The Central Nervous System ◽

Cervical Ganglia ◽

The enzyme tyrosine hydroxylase (TH) was immunohistochemically localized by the peroxidase-antiperoxidase method in rat to chromaffin cells of the adrenal medulla, large neurons and small darkly staining cells of the superior cervical ganglia and noradrenergic and dopaminergic neurons in brain. As compared with the conjugated peroxidase or immunofluorescence techniques, the peroxidase-antiperoxidase method gave the most selective and specific cytoplasmic localization of TH antisera in every tissue examined. The peroxidase staining with the TH antisera was more intense in dopaminergic than in noradrenergic neurons of the central nervous system. While TH was visualized in cell bodies of both dopaminergic and noradrenergic neurons, it could only be detected in axons and terminals in the dopaminergic system. The perikarya of noradrenergic neurons could be distinguished from dopaminergic neurons by the immunohistochemical demonstration of the enzyme dopamine-beta-hydroxylase only in the former.

Download Full-text