scholarly journals The Mixed Acid-Base Disturbances of Severe Canine Babesiosis

2001 ◽  
Vol 15 (5) ◽  
pp. 445-452 ◽  
Author(s):  
Andrew L. Leisewitz ◽  
Linda S. Jacobson ◽  
Helio S.A. Morais ◽  
Fred Reyers
Keyword(s):  
Canine Babesiosis ◽  
Acid Base ◽  
Mixed Acid

scholarly journals Acid-base status in canine babesiosis caused by Babesia canis

2020 ◽  
Vol 90 (6) ◽  
pp. 603-610
Author(s):  
Marin Torti ◽  
◽  
Josipa Kuleš ◽  
Vesna Matijatko ◽  
Mirna Brkljačić ◽  
...  
Keyword(s):  
Metabolic Acidosis ◽  
Metabolic Alkalosis ◽  
Strong Ion Difference ◽  
Canine Babesiosis ◽  
Acid Base ◽  
Mixed Acid ◽  
Naturally Occurring ◽  
Base Disorder ◽  
Acid Base Status ◽  
Healthy Dogs

Acid-base disturbances have been reported in severe canine babesiosis caused by Babesia rossi (B. rossi), but they have not been studied in babesiosis caused by B. canis. The objective of this study was to determine the acid-base status, blood gases and electrolyte concentrations in naturally occurring canine babesiosis caused by B. canis, and to compare the results to those in healthy dogs. Two groups of animals were used: group 1 consisted of 10 healthy dogs, and group 2 consisted of 14 dogs naturally infected with B. canis. The following acid-base disturbances occurred in the dogs with naturally occurring babesiosis: half of the dogs had a mixed acid-base disorder, and the other half a simple acid-base disorder. The most common mixed disorder was metabolic acidosis with metabolic alkalosis. It may be said that a variety of acid-base disorders occurs in canine babesiosis. The dogs in the present study had metabolic acidosis due to hyperlactemia and hyperchloremia, metabolic alkalosis due to hypochloremia and hypoalbuminemia, and respiratory alkalosis due to hypoxemia. With the use of the strong-ion difference approach clearer recognition of mixed acid-base disorders and their better understanding is possible.

Mixed Acid-Base Abnormality in a Patient with Herbicide Poisoning - Possible Insights on the Mechanism of Toxicity

2016 ◽  
Vol 23 (1) ◽  
pp. 104
Author(s):  
Rubina Khullar Mahajan ◽  
BinilaChacko ◽  
Vignesh Kumar Chandiraseharan ◽  
John Victor Peter
Keyword(s):  
Acid Base ◽  
Mixed Acid ◽  
Mechanism Of Toxicity

Mixed Acid–Base Disorders

2019 ◽  
pp. 243-255 ◽  
Author(s):  
Alluru S. Reddi
Keyword(s):  
Acid Base ◽  
Mixed Acid

Mixed Acid Base Disturbances: A Clinical Approach

1981 ◽  
Vol 65 (2) ◽  
pp. 347-361 ◽  
Author(s):  
Margaret Bia ◽  
Samuel O. Thier
Keyword(s):  
Clinical Approach ◽  
Acid Base ◽  
Mixed Acid

Mixed Acid-Base Disorders

2006 ◽  
pp. 296-309 ◽  
Author(s):  
Helio Autran de Morais ◽  
Andrew L. Leisewitz
Keyword(s):  
Acid Base ◽  
Mixed Acid

scholarly journals Acid based disorders in intensive care unit: a hospital-based study

2019 ◽  
Vol 6 (1) ◽  
pp. 62 ◽  
Author(s):  
Babu Rajendran ◽  
Seetha Rami Reddy Mallampati ◽  
Sheju Jonathan Jha J.
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Metabolic Acidosis ◽  
Infectious Diseases ◽  
Respiratory Alkalosis ◽  
Simple Type ◽  
Acid Base ◽  
Icu Patients ◽  
Mixed Acid ◽  
Base Disorder

Background: Acid base disorders are common in the ICU patients and pose a great burden in the management of the underlying condition.Methods: Identifying the type of acid-base disorders in ICU patients using arterial blood gas analysis This was a retrospective case-controlled comparative study. 46 patients in intensive care unit of a reputed institution and comparing the type of acid-base disorder amongst infectious (10) and non-infectious (36) diseases.Results: Of the study population, 70% had mixed acid base disorders and 30% had simple type of acid base disorders. It was found that sepsis is associated with mixed type of acid-base disorders with most common being metabolic acidosis with respiratory alkalosis. Non-infectious diseases were mostly associated with metabolic alkalosis with respiratory acidosis. Analysis of individual acid base disorders revealed metabolic acidosis as the most common disturbance.Conclusions: These results projected the probability of acid bases disorders in various conditions and help in the efficient management. Mixed acid base disorders are the most common disturbances in the intensive care setup which is metabolic acidosis with respiratory alkalosis in infectious diseases and metabolic acidosis is the most common simple type of acid base disorder.

Effect of potassium depletion on cerebrospinal fluid bicarbonate homeostasis

1976 ◽  
Vol 231 (2) ◽  
pp. 579-587 ◽  
Author(s):  
EE Nattie ◽  
SM Tenney
Keyword(s):  
Potassium Depletion ◽  
Acid Base Balance ◽  
Acid Base ◽  
Arterial Pco2 ◽  
Mixed Acid ◽  
Base Balance ◽  
Upward Direction ◽  
Relationship Of ◽  
The Relationship ◽  
K Depletion

We have examined the effect of K depletion on CSF [HCO3-] homeostasis in awake rats. The relationship of CSF [HCO3-] to arterial [HCO3-] in metabolic acid-base disturbances is displaced is an upward direction and has a significantly increased slope in K-depleted vs. control rats (0.51 +/- 0.02 vs. 0.42 +/- 0.02). Results of partial K-repletion experiments, with peripheral acid-base balance held constant, suggest that the effect is K specific. The K-depleted animals also exhibit a wider (CSF-arterial) PCO2 difference than controls (11.1 vs. 8.4 mmHg). When CSF [HCO3-] is shown as a function of CSF PCO2 the data of K-depleted rats are no longer displaced when compared to controls but still have a significantly greater slope (1.21 +/- 0.23 vs. 0.89 +/- 0.08). This increased slope is interpreted to reflect enhanced HCO3- movement from blood to CSF at high arterial [HCO3-]. Analysis of our data and observations from the literature in conditions of mixed acid-base disturbances suggest that CSF [HCO3-] is determined by a) CSF PCO2 and b) the level of arterial [HCO3-] when the latter is greater than the normal CSF [HCO3-].

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