scholarly journals Repair of large segmental bone defects using bone marrow stromal cells with demineralized bone matrix

2009 ◽  
Vol 1 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Jian-zhong Xu ◽  
Hui Qin ◽  
Xu-quan Wang ◽  
Qiang Zhou ◽  
Fei Luo ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Bone Defects ◽  
Marrow Stromal Cells ◽  
Segmental Bone ◽  
Demineralized Bone ◽  
Segmental Bone Defects

A bone regeneration strategy via dual delivery of demineralized bone matrix powder and hypoxia-pretreated bone marrow stromal cells using an injectable self-healing hydrogel

2021 ◽  
Author(s):  
Donghai Li ◽  
Zhouyuan Yang ◽  
Xin Zhao ◽  
Yue Luo ◽  
Yi Ou ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Regeneration ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Marrow Stromal Cells ◽  
Self Healing ◽  
Matrix Powder ◽  
Demineralized Bone

Dual delivery of demineralized bone matrix (DBM) powder and hypoxia-pretreated bone marrow stromal cells (BMSCs) using an injectable self-healing hydrogel enhances bone regeneration.

scholarly journals The effect of bone allografts combined with bone marrow stromal cells on the healing of segmental bone defects in a sheep model

2014 ◽  
Vol 10 (1) ◽  
pp. 36 ◽  
Author(s):  
Marco Bernardo C Fernandes ◽  
João Antônio Guimarães ◽  
Priscila Casado ◽  
Amanda dos Cavalcanti ◽  
Natalia N Gonçalves ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Bone Defects ◽  
Marrow Stromal Cells ◽  
Sheep Model ◽  
Bone Allografts ◽  
Segmental Bone ◽  
Segmental Bone Defects

scholarly journals Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium Phosphate/Collagen Scaffolds

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Xuehui Zhang ◽  
Mingming Xu ◽  
Xinggang Liu ◽  
Feng Zhang ◽  
Yan Wei ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Tricalcium Phosphate ◽  
Bone Marrow Stromal Cells ◽  
Autologous Bone Marrow ◽  
Bone Defects ◽  
Marrow Stromal Cells ◽  
Collagen Scaffolds ◽  
Autologous Bone

Nano-β-tricalcium phosphate/collagen (n-β-TCP/Col) is considered with good osteoconductivity. However, the therapeutic effectiveness of n-β-TCP/Col scaffolds in combination with autologous bone marrow stromal cells (BMSCs) remains to be elucidated for the repair of critical-sized bone defects. In this study, we found that n-β-TCP/Col scaffolds exhibited high biocompatibilityin vitro. The introduction of BMSCs expandedin vitroto the scaffolds dramatically enhanced their efficiency to restore critical-sized bone defects, especially during the initial stage after implantation. Collectively, these results suggest that autologous BMSCs in n-β-TCP/Col scaffolds have the potential to be applied in bone tissue engineering.

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