scholarly journals Creatine kinase and renal sodium excretion in African and European men on a high sodium diet

2018 ◽  
Vol 20 (2) ◽  
pp. 334-341 ◽  
Author(s):  
Lizzy M. Brewster ◽  
Inge Oudman ◽  
Rani V. Nannan Panday ◽  
Inna Khoyska ◽  
Yentl C. Haan ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Sodium Excretion ◽  
High Sodium ◽  
Sodium Diet ◽  
Renal Sodium Excretion ◽  
High Sodium Diet

A2866 Blood Pressure and Renal Sodium Excretion in African and European Men on a High sodium diet

2018 ◽  
Vol 36 ◽  
pp. e284
Author(s):  
Fares Karamat ◽  
Joseph Clark ◽  
Gert A van Montfrans ◽  
Lizzy M Brewster
Keyword(s):  
Blood Pressure ◽  
Sodium Excretion ◽  
High Sodium ◽  
Sodium Diet ◽  
Renal Sodium Excretion ◽  
High Sodium Diet

Comparison of systemic and direct intrarenal angiotensin II blockade on sodium excretion in rats

1995 ◽  
Vol 269 (1) ◽  
pp. F40-F46 ◽  
Author(s):  
Y. Peng ◽  
F. G. Knox
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Mean Arterial Pressure ◽  
Sodium Excretion ◽  
Systemic Effects ◽  
Ang Ii ◽  
High Sodium ◽  
Sodium Diet ◽  
High Sodium Diet ◽  
Interstitial Infusion

To dissociate the renal effects from the systemic effects of angiotensin II blockade, the present study was designed to determine the effects of systemic and renal interstitial infusion of the specific angiotensin II (ANG II) receptor antagonist, losartan, on blood pressure and sodium excretion in rats fed a low-, normal, or high-sodium diet. Fractional sodium excretion (FENa) and mean arterial pressure (MAP) were measured in rats before and during systemic infusion of losartan (10 mg/kg) or renal interstitial infusion of losartan (3 mg/kg) by means of a chronically implanted matrix. In rats fed a low- or normal sodium diet, systemic infusion of losartan markedly decreased MAP (delta -21 +/- 2, delta -10 +/- 2 mmHg, respectively; P < 0.05) with an accompanying fall in FENa (delta -0.10 +/- 0.05, delta -0.91 +/- 0.40%, respectively; P < 0.05). In contrast, preferential blockade of renal ANG II with renal interstitial losartan infusion resulted in an increase in FENa (delta 0.13 +/- 0.04, delta 0.95 +/- 0.45%, respectively; P < 0.05) and no significant change in MAP. In rats fed a high-sodium diet, both systemic and renal interstitial infusion of losartan increased FENa (delta 1.90 +/- 0.26, delta 1.40 +/- 0.56%, respectively; P < 0.05). Although systemic infusion of losartan decreased MAP (delta -4.4 +/- 0.6 mmHg, P < 0.05) in rats fed a high-sodium diet, the reduction in MAP was much less than that in rats fed a low- and normal sodium diet.(ABSTRACT TRUNCATED AT 250 WORDS)

Urodilatin is involved in sodium homeostasis and exerts sodium-state-dependent natriuretic and diuretic effects

1996 ◽  
Vol 271 (3) ◽  
pp. F489-F497 ◽  
Author(s):  
M. Meyer ◽  
R. Richter ◽  
R. Brunkhorst ◽  
E. Wrenger ◽  
P. Schulz-Knappe ◽  
...  
Keyword(s):  
Sodium Excretion ◽  
Sodium Balance ◽  
Sodium Homeostasis ◽  
High Sodium ◽  
Renal Response ◽  
Sodium Diet ◽  
Male Volunteers ◽  
State Dependent ◽  
High Sodium Diet

Urodilatin is involved in sodium homeostasis exerts sodium-state-dependent natriuretic and diuretic cts. Eight male volunteers participated in a study consisting of three consecutive phases of 7 days each. The volunteers a sodium diet with 52, 172.6, and 347.8 mmol um/day. Sodium excretion increased from 57.4 +/- 3.7 via .8 +/- 4.6 (P < 0.001) to 322.5 +/- 10.2 mmol/24 h (P < 0.001) at the end of each sodium diet. Urinary urodilatin excretion increased from 24.8 +/- 3.0 via 35.5 +/- 9.0 (P = 0.07) to 49.0 = mol/min (P < 0.01). At the end of each diet, urodilatin was infused for 2 h at 20 ng.kg body wt-1.min-1. Natriuresis increased after low- (4.1 to 52.9 mmol/h, P < 0.001), normal (6.9 to 44.9 mmol/h, P < 0.05), and high-sodium diet (20.1 to 102.9 mmol/h, P < 0.001). Diuresis increased from 174 to 709 (P < 0.001), 395 to 1,026 (P < 0.05), and 266 to 1,339 ml/h < 0.001). The present results indicate that endogenous urodilatin plays an important role in sodium homeostasis and that renal response to exogenous urodilatin is modulated by sodium balance.

scholarly journals Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet

2000 ◽  
Vol 130 (6) ◽  
pp. 1339-1347 ◽  
Author(s):  
Markus Lassila ◽  
Piet Finckenberg ◽  
Anna-Kaisa Pere ◽  
Leena Krogerus ◽  
Juhani Ahonen ◽  
...  
Keyword(s):  
Cyclosporine A ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
High Sodium ◽  
Sodium Diet ◽  
Induced Hypertension ◽  
High Sodium Diet

P1-93 Prenatal hyperglycemia alters kallikrein activity response to high sodium diet in adult rats

2007 ◽  
Vol 83 ◽  
pp. S108
Author(s):  
S.P. Salas ◽  
A. Giacaman ◽  
F.J. Guarda ◽  
J. Acosta ◽  
C.P. Vío
Keyword(s):  
Adult Rats ◽  
High Sodium ◽  
Sodium Diet ◽  
Activity Response ◽  
Kallikrein Activity ◽  
High Sodium Diet

scholarly journals Effects of High Sodium Diet on Dopaminergic Mechanism in Normal and Hypertensive Subjects

1988 ◽  
Vol 64 (11) ◽  
pp. 1157-1168
Author(s):  
Masaki TAKAHASHI ◽  
Yukio MIURA ◽  
Naoki SANO ◽  
Takashi OHZEKI ◽  
Takashi SUGAWARA ◽  
...  
Keyword(s):  
High Sodium ◽  
Sodium Diet ◽  
Dopaminergic Mechanism ◽  
High Sodium Diet

scholarly journals INFLUENCE OF MATERNAL HIGH SODIUM DIET ON SYSTEMIC AND RENAL RENIN ANGIOTENSIN ALDOSTERONE SYSTEM OF MALES AND FEMALES OFFSPRING WISTAR RATS

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Débora Rothstein Ramos ◽  
Nauilo Lima Costa ◽  
Karen Lucasechi Lopes Jang ◽  
Ivone Braga Oliveira ◽  
Luzia Naoko Shinohara Furukawa
Keyword(s):  
Wistar Rats ◽  
Renin Angiotensin Aldosterone System ◽  
Renin Angiotensin ◽  
High Sodium ◽  
Sodium Diet ◽  
Males And Females ◽  
High Sodium Diet

Upregulation of renal eNOS by high-sodium diet facilitates hypertension in doxorubicin-treated rats through enhanced oxidative stress

Toxicology ◽  
2006 ◽  
Vol 225 (2-3) ◽  
pp. 81-89 ◽  
Author(s):  
Toshihisa Hirai ◽  
Kenji Okumura ◽  
Yasuhiro Nishimoto ◽  
Takanori Shumiya ◽  
Ryuichiro Murakami ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
High Sodium ◽  
Sodium Diet ◽  
High Sodium Diet
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