Current Status of Evidence for a New Diagnosis: Food Addiction-A Literature Review

Food addiction is considered an important link for a better understanding of psychiatric and medical problems triggered by dysfunctions of eating behaviors, e. g., obesity, metabolic syndrome, binge eating disorder, or bulimia nervosa. At behavioral level, food addiction has high degrees of similarity with other eating disorders, a phenomenon that creates difficulties in finding specific diagnostic criteria. Food addiction has been also described as “eating addiction” or “eating dependence” by several researchers, who placed the emphasis on the behavior and not on the food itself. High-sodium foods, artificially flavored-foods, rich carbohydrate- and saturated fats-containing foods are triggers for the activation of the same neural pathways, therefore they act similarly to any drug of abuse. Food addiction is considered a disorder based on functional negative consequences, associated distress and potential risks to both psychological well-being and physical health. A clinical scale was validated for the quantification of the eating addiction severity, namely the Yale Food Addiction Severity Scale (YFAS), constructed to match DSM IV criteria for substance dependence. Using this instrument, a high prevalence of food addiction was found in the general population, up to 20% according to a meta-analytic research. The pathogenesis of this entity is still uncertain, but reward dysfunction, impulsivity and emotion dysregulation have been considered basic mechanisms that trigger both eating dysfunctions and addictive behaviors. Genetic factors may be involved in this dependence, as modulators of higher carbohydrate and saturate fat craving. Regarding the existence of potential therapeutic solutions, lorcaserin, antiepileptic drugs, opioid antagonists, antiaddictive agents are recommended for obesity and eating disorders, and they may be intuitively used in food addiction, but clinical trials are necessary to confirm their efficacy. In conclusion, a better understanding of food addiction's clinical profile and pathogenesis may help clinicians in finding prevention- and therapeutic-focused interventions in the near future.

Influence of Waste Glass Powder Addition on the Microstructure and Mechanical Properties of Autoclaved Building Materials

Lime quartz samples in which ground quartz sand was gradually substituted with waste glass powder (GP) were obtained under hydrothermal conditions to determine the influence of GP addition on the microstructure (observed by SEM), phase composition (analyzed by XRD), and compressive strength of autoclaved building materials. An additional series containing analytical grade NaOH and no GP was formed to evaluate the effect of sodium ions on tobermorite formation and its impact on the mechanical properties of the samples. GP addition hindered the formation of tobermorite during autoclaving. Instead, a higher amount of an amorphous and semi-crystalline C–S–H phase formed, leading to the densification of the composite matrix. Nevertheless, tobermorite-like structures were found during both XRD and SEM analyses, proving that the presence of small amounts of Al3+ ions allowed, to an extent, for the stabilization of the phase despite the high sodium content. The compressive strength values indicate that the presence of alkali in the system and the resulting formation of additional portions of C–S–H have a beneficial influence on the mechanical properties of autoclaved composites. However, the effect fades with increasing glass powder content which, together with a slight expansion of the samples, suggests that at high sand substitution levels, an alkali–silica reaction takes place.

Pengaruh Senam Aerobik Low Impact Terhadap Tekanan Darah Pada Lansia dengan Hipertensi : Literature Review

Hypertension is the most common degenerative disease suffered by the elderly. It caused by variuos factors, such as age, history of hypertension, high sodium consumption and lack of physical activity. Exercise suc as low impact aerobic can reduce heart rate related to decrease in cardiac output. Consequently, blood pressure will decrease gradually. The purpose of the study was to describe the effect of low impact aerobic exercise on blood pressure in elderly with hypertension. The study used a literature review, by accessing the Garuda and ProQuest database using the keyword “Hypertension” AND “Elderly” AND “Low Impact Aerobic Exercise” AND “Blood Pressure”. The result show that there is an effect of low impact aerobic exercise on blood pressure in the elderly with hypertension. After the interventions, the systolic and dyastolic blood pressure was decrease 10.16 mmHg ang 5,02 mmHg, respectively. Low impact aerobic exercise is effective in decrease blood pressure in elderly with hypertension. Low impact aerobic exercise can be an alternative to overcome the problem of hypertension among elderly in family, community and gerontology nursing settings.Keywords: Blood Pressure, elderly, Hypertension, low Impact Aerobics AbstrakHipertensi merupakan penyakit degeneratif yang paling bnayak diderita oleh lansia. Hal ini disebabkan oleh berbagai faktor, seperti usia, riwayat penyakit hipertensi, konsumsi tinggi garam dan kurangnya aktivitas fisik. Latihan fisik seperti senam aerobik low impact dapat menurunkan denyut jantung dimana terjadi penurunan pada cardiac output yang akhirnya dapat menurunkan tekanan darah. Tujuan dari penelitian ini yaitu untuk mendeskripsikan pengaruh senam aerobik low impact terhadap tekanan darah pada lansia dalam literature review. Metode yang digunakan dalam penelitian ini adalah literature review, dengan mengakses database Portal Garuda dan Proquest dengan menggunakan kata kunci “Hipertensi” DAN ”Lansia” DAN ”Senam Aerobik Low Impact” DAN ”Tekanan Darah”. Hasil penelitian ini menunjukkan bahwa terdapat pengaruh senam aerobik low impact terhadap tekanan darah pada lansia dengan hipertensi yang ditandai dengan adanya penurunan nilai sistole dan diastole setelah diberikan intervensi senam aerobik low impact. Hasil penelitian ini diketahui terdapat pengaruh senam aerobik low impact terhadap tekanan darah pada lansia dengan hipertensi, diharapkan dapat menjadi referensi di keperawatan keluarga maupun komunitas pada lansia untuk meningkatkan aktivitas senam aerobik low impact dalam mengatasi masalah hipertensi pada lansia.Kata kunci : Hipertensi, Lansia, Senam Aerobik Low Impact, Tekanan Darah

THE DETERMINANT OF THE INCIDENT OF HYPERTENSION IN BALEKAMBANG HELATH CENTER, BENDUNGAN VILLAGE, JONGGOL SUB - DISTRIC, IN THE YEAR 2021

Introduction: Hypertension is a condition of high blood pressure and as The Silent Killer because most are asymptomatic or asymptomatic. sethat treatment is often too late. The incidence of hypertension is influenced by several factors, such as obesity (obesity), alcohol consumption, sodium intake, and stress. The purpose of this research is to find outdeterminants of the incidence of hypertension in Balekambang Health Center. Method: This type of research is analytic observational using a cross sectional research design. The sampling technique used in this study is Probability Sampling with Simple Random Sampling with a total sample of 86 respondents using the chi square test. Results: The results of this study are the majority of the respondents' ages are included in the early elderly, namely the age of 46-55 years (26.7%), the most gender is female (61.6%) and the majority have low education (65.1%), the majority of respondents do not experience obesity (76.7%), the majority of respondents do not consume alcohol (81.4%), more respondents have high sodium intake (59.3%) and the majority of respondents experience stress (51.2%). Conclusion: The conclusion of this study obtained that the factors associated with the incidence of hypertension are overweight/obesity (p-value = 0.001), sodium intake (p-value = 0.001), and stress (p-value = 0.001). Meanwhile, there is no relationship between the incidence of hypertension and alcohol consumption (p-value = 0.055). Health services can improve health promotion efforts regarding prevention of hypertension cases through education to overcome obesity, alcohol consumption, high sodium intake and stress.

Association of rheumatoid arthritis and high sodium intake with major adverse cardiovascular events: a cross-sectional study from the seventh Korean National Health and Nutrition Examination Survey

ObjectivesHigh salt intake has a harmful effect on hypertension; however, the association between major adverse cardiovascular events (MACE) and salt intake is still controversial. Rheumatoid arthritis (RA) is also characterised by excess cardiovascular risk. However, few studies have investigated the combined role of salt intake and RA in MACE in the general Korean population. Here, we evaluated this relationship among the Korean adult population.DesignRetrospective, cross-sectional.SettingPopulation-based survey in Korea.MethodsThis study was based on the data of the seventh Korean National Health and Nutrition Examination Survey (2016–2018). The estimated 24-hour urinary sodium excretion (24HUNa), a surrogate marker for daily sodium intake, was calculated using the Tanaka equation and was stratified into five groups (<3, 3–3.999, 4–4.999, 5–5.999 and ≥6 g/day). Finally, data from 13 464 adult participants (weighted n=90 425 888) were analysed; all analyses considered a complex sampling design. Multivariable logistic regression for MACE as primary dependent variable was performed and adjusted for potential covariates.ResultsParticipants with MACE had higher 24HUNa levels and RA proportion than those without MACE (p<0.001). The association of MACE with 24HUNa was J-shaped with a gradual increase from about 3 g/day. The highest 24HUNa (≥6 g/day) group was significantly associated with increased prevalence of MACE compared with the reference group (3–3.999 g/day) after adjusting for all associated covariates (OR 6.75, 95% CI 1.421 to 32.039). In the multivariate logistic regression analysis, RA (OR 2.05, 95% CI 1.283 to 3.264) and the highest 24HUNa group (OR 6.35, 95% CI 1.337 to 30.147) were significantly associated with MACE even after adjusting for baseline covariates.ConclusionsThese nationally representative data suggest that RA and extremely high sodium intake are associated with MACE in the general adult Korean population. Avoiding extremely high salt intake and considering RA as an important risk factor for MACE might help promote public cardiovascular health.

Temporal trend of gastric cancer burden along with its risk factors in China from 1990 to 2019, and projections until 2030: comparison with Japan, South Korea, and Mongolia

Background Identifying and projecting the epidemiological burden of gastric cancer (GC) can optimize the control strategies, especially in high-burden areas. Methods We collected incidence, deaths, disability-adjusted life-years (DALYs), age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), age-standardized DALY rate (ASDR) of GC from 1990 to 2019 in China, Japan, South Korea, and Mongolia from the Global Burden of Disease Study 2019. The average annual percentage change (AAPC) was calculated to quantify the temporal trends, and the projection was estimated by applying the Bayesian age-period-cohort model. Results In China, the ASIR of GC declined slightly from 37.56/100000 in 1990 to 30.64/100000 in 2019 (AAPC of − 0.41), while the declines of ASMR and ASDR were pronounced (AAPC of − 1.68 and − 1.98, respectively), which were weaker than Japan and South Korea. Although the age-standardized rates of gastric cancer in most countries have declined overall in the past 30 years, the downward trend in the last 4 years has become flattened. Smoking remained one main contributor to DALYs of GC in China, Japan, South Korea, and Mongolia, with more than 24%. The contribution from high-sodium diet was similar between men and women, and kept relatively stable over the three decades. The predicted ASMRs among the four East Asian countries continued to decline until 2030, but the absolute deaths would still increase significantly, especially in South Korea and Mongolia. Conclusions Although the age-standardized rates of GC in most countries have declined, the absolute burden of GC in the world, especially in China and Mongolia, is on the rise gradually. Low socio-demographic index and aging along with Helicobacter pylori infection, smoking, and high-salt diet were the main risk factors of GC occurrence and should be paid more attention.

Diet in Scleroderma: Is There a Need for Intervention?

Systemic sclerosis (SSc) patients exhibit a plethora of risk factors for nutritional decline, including the presence of chronic inflammation and the progressive nature of disease-related multisystem involvement. The prevalence and consequences of nutritional decline in scleroderma are frequently underestimated, its management currently remaining a subject of debate. The main objective of the present study was to perform a detailed assessment of scleroderma patients’ diet as well as their eating habits and to describe the relationships with weight loss and malnutrition risk in the absence of professional nutritional counseling. Methods: We used a translated and validated version of the EPIC-Norfolk FFQ (European Prospective Investigation into Cancer and Nutrition Norfolk Food Frequency Questionnaire) to evaluate the patients’ diet and MUST (Malnutrition Universal Screening Tool) to investigate the risk of malnutrition. Disease activity was estimated using the EUSTAR-AI (European Scleroderma Trials and Research group Activity Index). Results: We included 69 patients with SSc, of which 42 underwent a detailed dietary assessment. Dietary factors were connected to body composition and digestive symptoms. We found high sodium intake and frequent suboptimal energy consumption in our study group, including patients with cardiopulmonary involvement. Liver transaminases were inversely correlated with the consumption of nuts and seeds. Malnutrition and weight loss were significantly associated with pulmonary hypertension, heart failure, albumin levels, and the extent of skin fibrosis, but not advanced age. Although the patients with EUSTAR-AI ≥ 2.5 were more frequently included in the moderate and high malnutrition risk categories, these results did not reach statistical significance. Conclusions: Currently, there is an unmet need for longitudinal and interventional research focusing on the long-term significance, ramifications, and management of nutritional impairment in SSc patients with various clinical manifestations. Our results indicate that scleroderma patients could benefit from personalized nutritional counseling in an interdisciplinary setting.

The first observation of osmotically neutral sodium accumulation in the myocardial interstitium

The aim of this study was the detection and quantification of the Na+ depositions in the extracellular matrix of myocardial tissue, which are suggested to be bound by negatively charged glycosaminoglycan (GAG) structures. The presented experimental results are based on high resolution X-ray fluorescence (XRF) spectromicroscopy technique used to perform a comparative analysis of sodium containment in intracellular and interstitial spaces of cardiac tissues taken from animals selected by low and high sodium intake rates. The experimental results obtained show that high sodium daily intake can result in a remarkable increase of sodium content in the myocardial interstitium.