scholarly journals Will peripherally restricted kappa-opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential?

2016 ◽  
Vol 41 (4) ◽  
pp. 371-382 ◽  
Author(s):  
A. Albert-Vartanian ◽  
M. R. Boyd ◽  
A. L. Hall ◽  
S. J. Morgado ◽  
E. Nguyen ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Opioid Receptor ◽  
Kappa Opioid Receptor ◽  
Abuse Potential ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Relieve Pain ◽  
Opioid Receptor Agonists

scholarly journals Cover Feature: Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists (12/2021)

ChemMedChem ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. 1834-1834
Author(s):  
Veena D. Yadav ◽  
Lalan Kumar ◽  
Poonam Kumari ◽  
Sakesh Kumar ◽  
Maninder Singh ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Kappa Opioid Receptor ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Opioid Receptor Agonists

EVIDENCE FOR A CENTRAL OPIOID CONTROL OF RUMINATION

1984 ◽  
Vol 64 (5) ◽  
pp. 13-15 ◽  
Author(s):  
Y. RUCKEBUSCH ◽  
TH. BARDON
Keyword(s):  
Key Words ◽  
Opioid Receptor ◽  
Opioid Receptors ◽  
Opioid Peptides ◽  
Kappa Opioid Receptor ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Opioid Agonists ◽  
Reflex Control ◽  
Opioid Receptor Agonists

Intravenous adrenaline induced reticular extracontractions and rumination within 26 sec in hay-fed, and 184 sec in cube-fed sheep. Regardless of diet, pretreatment with cerebroventricular infusion of kappa-opioid-receptor agonists enhanced this reflex. Control of rumination may involve multiple opioid-receptors, since inhibition of the reflex occurred after mu- and delta-opioid-agonists. Key words: Sheep, rumination, opioid-peptides

Kappa-opioid receptor agonists in pain treatment

2019 ◽  
Vol 44 (1) ◽  
pp. 39
Author(s):  
Jr., J.V. Pergolizzi ◽  
J.A. LeQuang ◽  
Jr., R. Taylor ◽  
M.H. Ossipov ◽  
R.B. Raffa
Keyword(s):  
Opioid Receptor ◽  
Pain Treatment ◽  
Kappa Opioid Receptor ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Opioid Receptor Agonists
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