Reply to sentinel lymph node biopsy (SLNB) plus wide local excision vs. wide local excision alone for primary cutaneous melanoma: a systematic review and meta-analysis - SLNB is not associated with a significantly better outcome in melanoma survival

2017 ◽  
Vol 31 (10) ◽  
pp. e471-e472 ◽  
Author(s):  
K. Eisendle
2018 ◽  
Author(s):  
Clara R Farley ◽  
Keith A Delman ◽  
Michael C Lowe

Melanoma presents a significant health burden as its incidence continues to rise in both sexes and remains the most common cause of skin cancer–related death. Risk factors for the development of melanoma include sun exposure, fair complexion, increasing age, previous melanoma, multiple dysplastic nevi, and familial syndromes. Wide local excision is the standard of care for those with early forms of melanoma, with sentinel lymph node biopsy in appropriate populations. Sentinel lymph node status contributes to the discussion as to whether to pursue completion lymphadenectomy. This review outlines surgical treatment of primary cutaneous melanoma, including wide local excision, sentinel lymph node biopsy, and completion lymphadenectomy.   This review contains 10 figures, 4 tables and 33 references Key words: biopsy, cutaneous, lymphadenectomy, margin, melanoma, pathology, primary, sentinel node, surgery, treatment  


2018 ◽  
Author(s):  
Clara R Farley ◽  
Keith A Delman ◽  
Michael C Lowe

Melanoma presents a significant health burden as its incidence continues to rise in both sexes and remains the most common cause of skin cancer–related death. Risk factors for the development of melanoma include sun exposure, fair complexion, increasing age, previous melanoma, multiple dysplastic nevi, and familial syndromes. Wide local excision is the standard of care for those with early forms of melanoma, with sentinel lymph node biopsy in appropriate populations. Sentinel lymph node status contributes to the discussion as to whether to pursue completion lymphadenectomy. This review outlines surgical treatment of primary cutaneous melanoma, including wide local excision, sentinel lymph node biopsy, and completion lymphadenectomy.   This review contains 10 figures, 2 tables and 33 references Key words: biopsy, cutaneous, lymphadenectomy, margin, melanoma, pathology, primary, sentinel node, surgery, treatment  


2014 ◽  
Vol 110 (12) ◽  
pp. 2837-2846 ◽  
Author(s):  
C Meads ◽  
A J Sutton ◽  
A N Rosenthal ◽  
S Małysiak ◽  
M Kowalska ◽  
...  

Cancer ◽  
2006 ◽  
Vol 107 (11) ◽  
pp. 2647-2652 ◽  
Author(s):  
Christopher J. Gannon ◽  
Dennis L. Rousseau ◽  
Merrick I. Ross ◽  
Marcella M. Johnson ◽  
Jeffrey E. Lee ◽  
...  

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