scholarly journals Difference in Muscle Quality over the Adult Life Span and Biological Correlates in the Baltimore Longitudinal Study of Aging

2014 ◽  
Vol 62 (2) ◽  
pp. 230-236 ◽  
Author(s):  
Ann Zenobia Moore ◽  
Giorgio Caturegli ◽  
E. Jeffrey Metter ◽  
Sokratis Makrogiannis ◽  
Susan M. Resnick ◽  
...  
2019 ◽  
Vol 75 (2) ◽  
pp. 394-400 ◽  
Author(s):  
Scott D Moffat ◽  
Yang An ◽  
Susan M Resnick ◽  
Michael P Diamond ◽  
Luigi Ferrucci

Abstract Background Cortisol is a key stress hormone implicated in the pathogenesis of many age-related diseases. Longitudinal information on cortisol exposure has been restricted to animal models and a small number of human studies. The purpose of the present study was to quantify longitudinal change in cortisol across the adult life span. Methods We conducted a prospective longitudinal study of 24-hour urinary free cortisol excretion from ages 20 to 90 years and older. Participants were 1,814 men and women from the Baltimore Longitudinal Study of Aging who provided a total of 5,527 urine specimens for analysis. The average duration of longitudinal follow-up was 6.6 years. The primary outcome measure was 24-hour urinary free cortisol to creatinine ratio (UFC/Cr) as determined by liquid chromatography/mass spectrometry. Results UFC/Cr follows a U-shaped pattern across the life span with decreases in UFC/Cr in the 20s and 30s, relative stability in the 40s and 50s, and increases thereafter. This pattern of change was robust with respect to adjustment for several potential confounding factors. Conclusions Age-related changes in cortisol exposure raise important questions about the potential protective or exacerbating role of cortisol exposure in predicting medical, physiological, and behavioral outcomes.


1996 ◽  
Vol 41 (6) ◽  
pp. 590-591
Author(s):  
Barbara R. Bjorklund
Keyword(s):  

2006 ◽  
Vol 21 (2) ◽  
pp. 303-317 ◽  
Author(s):  
Carol Magai ◽  
Nathan S. Consedine ◽  
Yulia S. Krivoshekova ◽  
Elizabeth Kudadjie-Gyamfi ◽  
Renee McPherson

2008 ◽  
Author(s):  
Katie Finley ◽  
Joan C. Borod ◽  
Adam Brickman ◽  
J. M. Schmidt ◽  
Stephanie Assuras ◽  
...  

2008 ◽  
Author(s):  
Sandra Hale ◽  
Mitchell S. Sommers ◽  
Joel Myerson ◽  
Nancy Tye-Murray ◽  
Nathan Rose ◽  
...  

2006 ◽  
Author(s):  
Mark E. Faust ◽  
Kristi S. Multhaup ◽  
Patricia A. Brooks ◽  
Sarah Frey ◽  
Blair Hicks ◽  
...  

Author(s):  
Michael W. Pratt ◽  
M. Kyle Matsuba ◽  
Heather L. Lawford ◽  
Feliciano Villar

This chapter addresses the development of generativity, Erikson’s conception of the midlife strength in his eight-stage model of personality development. Following Erikson, the authors define generativity as care for next generations and set it in the context of both personality theory and life span development. Specifically, the authors draw on the framework of McAdams that characterizes personality as composed of three sequentially developing levels: actions, goals/motives, and the narrative life story (a mature form of narrative that provides the self with a sense of meaning and identity). The authors then review research on generativity as expressed from adolescence to later adulthood, which indicates that it is a relevant construct across this entire period in a variety of life domains. They also consider factors influencing generativity levels, including family background and cultural variations. Throughout the chapter, the authors consider the connections of generativity to morality across different facets of personality and stages of the adult life span.


Hypertension ◽  
2017 ◽  
Vol 69 (4) ◽  
pp. 712-720 ◽  
Author(s):  
Chang-Yang Xing ◽  
Takashi Tarumi ◽  
Rutger L. Meijers ◽  
Marcel Turner ◽  
Justin Repshas ◽  
...  

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