Effects of ML351 and tissue plasminogen activator combination therapy in a rat model of focal embolic stroke

Journal of Neurochemistry ◽

10.1111/jnc.15308 ◽

2021 ◽

Author(s):

Guangsen Cheng ◽

Wei Zhao ◽

Yongjie Xin ◽

Guomin Huang ◽

Yongkang Liu ◽

...

Keyword(s):

Combination Therapy ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Embolic Stroke ◽

Tissue Plasminogen

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Inhibition of PI3Kγ by AS605240 plus low-dose tissue plasminogen activator (tPA) combination improves thrombolytic therapy in a rat model of embolic stroke

Neuroscience Letters ◽

10.1016/j.neulet.2020.135339 ◽

2020 ◽

Vol 738 ◽

pp. 135339

Author(s):

Rong Jin ◽

Wei Zhong ◽

Shan Liu ◽

Min Wang ◽

Guohong Li

Keyword(s):

Thrombolytic Therapy ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Low Dose ◽

Embolic Stroke ◽

Tissue Plasminogen

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Extension of the Therapeutic Window for Recombinant Tissue Plasminogen Activator With Argatroban in a Rat Model of Embolic Stroke

Stroke ◽

10.1161/hs1101.097390 ◽

2001 ◽

Vol 32 (11) ◽

pp. 2635-2640 ◽

Author(s):

D. C. Morris ◽

L. Zhang ◽

Z. G. Zhang ◽

M. Lu ◽

K. L. Berens ◽

...

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Recombinant Tissue Plasminogen Activator ◽

Embolic Stroke ◽

Therapeutic Window ◽

Tissue Plasminogen

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Adjuvant Treatment With a Glycoprotein IIb/IIIa Receptor Inhibitor Increases the Therapeutic Window for Low-Dose Tissue Plasminogen Activator Administration in a Rat Model of Embolic Stroke

Circulation ◽

10.1161/01.cir.0000068374.57764.eb ◽

2003 ◽

Vol 107 (22) ◽

pp. 2837-2843 ◽

Author(s):

Li Zhang ◽

Zheng Gang Zhang ◽

Ruilan Zhang ◽

Daniel Morris ◽

Mei Lu ◽

...

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Adjuvant Treatment ◽

Rat Model ◽

Low Dose ◽

Embolic Stroke ◽

Therapeutic Window ◽

Tissue Plasminogen ◽

Receptor Inhibitor

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Early administration of pyrrolidine dithiocarbamate extends the therapeutic time window of tissue plasminogen activator in a male rat model of embolic stroke

Journal of Neuroscience Research ◽

10.1002/jnr.24186 ◽

2017 ◽

Vol 96 (3) ◽

pp. 449-458 ◽

Author(s):

Zhongxing Wang ◽

Weiran Shan ◽

Jiangbei Cao ◽

Max Wintermark ◽

Wenqi Huang ◽

...

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Time Window ◽

Embolic Stroke ◽

Male Rat ◽

Pyrrolidine Dithiocarbamate ◽

Early Administration ◽

Tissue Plasminogen ◽

Therapeutic Time Window

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Effects of Minocycline Plus Tissue Plasminogen Activator Combination Therapy After Focal Embolic Stroke in Type 1 Diabetic Rats

Stroke ◽

10.1161/strokeaha.111.000309 ◽

2013 ◽

Vol 44 (3) ◽

pp. 745-752 ◽

Author(s):

Xiang Fan ◽

Eng H. Lo ◽

Xiaoying Wang

Keyword(s):

Combination Therapy ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Diabetic Rats ◽

Embolic Stroke ◽

Tissue Plasminogen

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Interrelations between blood-brain barrier permeability and matrix metalloproteinases are differently affected by tissue plasminogen activator and hyperoxia in a rat model of embolic stroke

Medical Gas Research ◽

10.1186/2045-9912-2-2 ◽

2012 ◽

Vol 2 (1) ◽

pp. 2 ◽

Author(s):

Dominik Michalski ◽

Carsten Hobohm ◽

Christopher Weise ◽

Johann Pelz ◽

Marita Heindl ◽

...

Keyword(s):

Matrix Metalloproteinases ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Blood Brain Barrier ◽

Rat Model ◽

Embolic Stroke ◽

Barrier Permeability ◽

Blood Brain Barrier Permeability ◽

Brain Barrier Permeability ◽

Tissue Plasminogen

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Serum S100B indicates successful combination treatment with recombinant tissue plasminogen activator and MK-801 in a rat model of embolic stroke

Brain Research ◽

10.1016/j.brainres.2007.03.085 ◽

2007 ◽

Vol 1154 ◽

pp. 194-199 ◽

Author(s):

Yu Tanaka ◽

Toshiyuki Marumo ◽

Tomohiro Omura ◽

Shigeru Yoshida

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Combination Treatment ◽

Recombinant Tissue Plasminogen Activator ◽

Embolic Stroke ◽

Serum S100b ◽

Mk 801 ◽

Tissue Plasminogen

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Effects of Tissue Plasminogen Activator and Annexin A2 Combination Therapy on Long-Term Neurological Outcomes of Rat Focal Embolic Stroke

Stroke ◽

10.1161/strokeaha.113.003823 ◽

2014 ◽

Vol 45 (2) ◽

pp. 619-622 ◽

Author(s):

Xiaoshu Wang ◽

Xiang Fan ◽

Zhanyang Yu ◽

Zhengbu Liao ◽

Jianhua Zhao ◽

...

Keyword(s):

Combination Therapy ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Embolic Stroke ◽

Neurological Outcomes ◽

Tissue Plasminogen

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Whole body hypothermia extends tissue plasminogen activator treatment window in the rat model of embolic stroke

Life Sciences ◽

10.1016/j.lfs.2020.117450 ◽

2020 ◽

Vol 256 ◽

pp. 117450

Author(s):

Mahsa Hassanipour ◽

Mohammadreza Zarisfi ◽

Vahid Ehsani ◽

Mohammad Allahtavakoli

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Embolic Stroke ◽

Tissue Plasminogen ◽

Treatment Window

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Rapid Breakdown of Microvascular Barriers and Subsequent Hemorrhagic Transformation After Delayed Recombinant Tissue Plasminogen Activator Treatment in a Rat Embolic Stroke Model

Stroke ◽

10.1161/01.str.0000023534.37670.f7 ◽

2002 ◽

Vol 33 (8) ◽

pp. 2100-2104 ◽

Author(s):

Rick M. Dijkhuizen ◽

Minoru Asahi ◽

Ona Wu ◽

Bruce R. Rosen ◽

Eng H. Lo

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Hemorrhagic Transformation ◽

Embolic Stroke ◽

Stroke Model ◽

Tissue Plasminogen

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