Hypersensitivity reaction to RHA filler

Tattoos have become increasingly popular worldwide making adverse effects from tattoos a growing concern. In our report, we present a 51-year-old man who developed an unusual allergic reaction to the red ink portions of his tattoos that coincided with the initiation of ledipasvir/sofosbuvir treatment for his hepatitis C. Clinical and histological features were consistent with a delayed-type hypersensitivity reaction to red ink.

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Immediate hypersensitivity reaction followed by successful oral desensitization to ursodiol

Allergy Asthma & Clinical Immunology ◽

10.1186/s13223-021-00578-7 ◽

2021 ◽

Vol 17 (1) ◽

Author(s):

Erika Yue Lee ◽

Christine Song

Keyword(s):

Hypersensitivity Reaction ◽

Primary Biliary Cholangitis ◽

Line Treatment ◽

Second Line ◽

Immediate Hypersensitivity ◽

First Line ◽

Case Presentation ◽

Desensitization Protocol ◽

First Line Treatment ◽

Oral Desensitization

Abstract Background Immediate hypersensitivity reaction to ursodiol is rare and there is no previously published protocol on ursodiol desensitization. Case presentation A 59-year-old woman with primary biliary cholangitis (PBC) developed an immediate hypersensitivity reaction to ursodiol—the first-line treatment for PBC. When she switched to a second-line treatment, her PBC continued to progress. As such, she completed a novel 12-step desensitization protocol to oral ursodiol. She experienced recurrent pruritus after each dose following desensitization, which subsided after a month of being on daily ursodiol. Conclusion Immediate hypersensitivity reaction to ursodiol is uncommon. Our case demonstrated that this novel desensitization protocol to ursodiol could be safely implemented when alternative options are not available or have proven inferior in efficacy.

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Successful salvage treatment with paclitaxel, ifosfamide, and cisplatin in a patient with methotrexate‐resistant gestational trophoblastic neoplasia who developed hypersensitivity reaction to etoposide

Journal of Obstetrics and Gynaecology Research ◽

10.1111/jog.14945 ◽

2021 ◽

Author(s):

Noriko Yamaguchi ◽

Yoshinobu Hamada ◽

Risa Inagaki ◽

Kohei Nemoto ◽

Hideyuki Yoshitomi ◽

...

Keyword(s):

Hypersensitivity Reaction ◽

Salvage Treatment ◽

Gestational Trophoblastic Neoplasia

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Delayed hypersensitivity reaction to orodispersible budesonide in a case with eosinophilic esophagitis

BMC Gastroenterology ◽

10.1186/s12876-020-01554-y ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Caroline Michèle Andrist ◽

Lukas Jörg ◽

Thomas Greuter ◽

Anna Gschwend ◽

Alex Straumann ◽

...

Keyword(s):

Hypersensitivity Reaction ◽

Eosinophilic Esophagitis ◽

Systemic Reaction ◽

Chronic Inflammatory Disease ◽

Delayed Hypersensitivity ◽

Caucasian Woman ◽

Case Presentation ◽

Commercial Test ◽

Delayed Hypersensitivity Reaction ◽

Subsequent Intake

Abstract Background Eosinophilic esophagitis (EoE) is a chronic inflammatory disease that has been known since the early 1990s. Swallowed topical corticosteroids (STC) belong to the therapeutic cornerstones. We describe a delayed hypersensitivity reaction to Jorveza®, a newly developed orodispersible budesonide tablet licensed for the treatment of eosinophilic esophagitis. Case presentation A 32-year-old Caucasian woman with EoE was newly treated with Jorveza®. Hours after the first intake, she felt a “strange pruritus” in the throat. This sensation worsened with each subsequent intake. On day 4 she developed oral mucosal symptoms (paresthesia of the tongue, sore and an itchy throat). Intraoral, throat and facial swellings, but no systemic reaction were observed. Patch testing using two commercial test series as well as the orodispersible budesonide tablet revealed a strong sensitization, proving a T cell mediated allergy to budesonide. Conclusions Orodispersible budesonide is increasingly prescribed for the treatment of eosinophilic esophagitis. The development of oropharyngeal symptoms after initiating should alert the treating physician to the possibility of a hypersensitivity reaction.

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