Early vs late cardiac surgery in patients with native valve endocarditis—United States Nationwide Inpatient database

Streptobacillus moniliformis, the cause of rat-bite fever (RBF) in the United States, has rarely been reported as a cause of infectious endocarditis. In the majority of previously reported cases, the diagnosis was clinically based in patients with underlying valvular abnormalities in the setting of positive blood culture for Streptobacillus moniliformis. We report a case of native valve endocarditis secondary to Streptobacillus moniliformis in a woman with a mitral valve vegetation but negative blood cultures where the diagnosis was established using molecular diagnostics on the valvular tissue.

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Surgery for infective native valve endocarditis

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0032-1332696 ◽

2013 ◽

Vol 61 (S 01) ◽

Author(s):

M Wilbring ◽

SM Tugtekin ◽

K Matschke

Keyword(s):

Native Valve ◽

Native Valve Endocarditis

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The Role of the Coagulase-negative Staphylococci (CoNS) in Infective Endocarditis; A Narrative Review from 2000 to 2020

Current Pharmaceutical Biotechnology ◽

10.2174/1389201021666200423110359 ◽

2020 ◽

Vol 21 (12) ◽

pp. 1140-1153 ◽

Cited By ~ 1

Author(s):

Mohammad A. Noshak ◽

Mohammad A. Rezaee ◽

Alka Hasani ◽

Mehdi Mirzaii

Keyword(s):

Foreign Body ◽

Infective Endocarditis ◽

Prosthetic Valve ◽

Human Life ◽

Prosthetic Valve Endocarditis ◽

Surgical Site Infections ◽

Coagulase Negative Staphylococci ◽

Native Valve ◽

Native Valve Endocarditis

Coagulase-negative staphylococci (CoNS) are part of the microbiota of human skin and rarely linked with soft tissue infections. In recent years, CoNS species considered as one of the major nosocomial pathogens and can cause several infections such as catheter-acquired sepsis, skin infection, urinary tract infection, endophthalmitis, central nervous system shunt infection, surgical site infections, and foreign body infection. These microorganisms have a significant impact on human life and health and, as typical opportunists, cause peritonitis in individuals undergoing peritoneal dialysis. Moreover, it is revealed that these potential pathogens are mainly related to the use of indwelling or implanted in a foreign body and cause infective endocarditis (both native valve endocarditis and prosthetic valve endocarditis) in patients. In general, approximately eight percent of all cases of native valve endocarditis is associated with CoNS species, and these organisms cause death in 25% of all native valve endocarditis cases. Moreover, it is revealed that methicillin-resistant CoNS species cause 60 % of all prosthetic valve endocarditis cases. In this review, we describe the role of the CoNS species in infective endocarditis, and we explicated the reported cases of CoNS infective endocarditis in the literature from 2000 to 2020 to determine the role of CoNS in the process of infective endocarditis.

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Aspergillus fumigatus Skull Bone Osteomyelitis and Native Valve Endocarditis in a Young Boy: an Unusual Presentation of Chronic Granulomatous Disease

Journal of Clinical Immunology ◽

10.1007/s10875-020-00939-8 ◽

2021 ◽

Author(s):

Gummadi Anjani ◽

Ankur Kumar Jindal ◽

Ashwini Prithvi ◽

Harsimran Kaur ◽

Madhubala Sharma ◽

...

Keyword(s):

Aspergillus Fumigatus ◽

Chronic Granulomatous Disease ◽

Unusual Presentation ◽

Granulomatous Disease ◽

Skull Bone ◽

Native Valve ◽

Native Valve Endocarditis

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Peripartum native valve endocarditis without underlying risk factors

Indian Journal of Thoracic and Cardiovascular Surgery ◽

10.1007/s12055-021-01143-y ◽

2021 ◽

Author(s):

Riju Nair ◽

Subbaiyan Kumar ◽

Rajan Mani

Keyword(s):

Risk Factors ◽

Native Valve ◽

Native Valve Endocarditis ◽

Underlying Risk

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Gemella sanguinis: A rare cause of native valve endocarditis in a child

Medical Journal Armed Forces India ◽

10.1016/j.mjafi.2015.08.008 ◽

2016 ◽

Vol 72 ◽

pp. S84-S86 ◽

Cited By ~ 1

Author(s):

Mugunthan M ◽

Sharad Bhalla ◽

Vishal Shete ◽

Naveen Grover

Keyword(s):

Native Valve ◽

Native Valve Endocarditis

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External Validation of the Cardiac Surgery Score in a Quaternary Hospital in the United States of America

Journal of Intensive Care Medicine ◽

10.1177/08850666211066820 ◽

2021 ◽

pp. 088506662110668

Author(s):

Asha Singh ◽

Chen Liang ◽

Stephanie L. Mick ◽

Chiedozie Udeh

Keyword(s):

United States ◽

Cardiac Surgery ◽

United States Of America ◽

Predictive Accuracy ◽

External Validation ◽

Cleveland Clinic ◽

Area Under The Curve ◽

The United States ◽

Mortality Data ◽

The Usa

Background The Cardiac Surgery Score (CASUS) was developed to assist in predicting post-cardiac surgery mortality using parameters measured in the intensive care unit. It is calculated by assigning points to ten physiologic variables and adding them to obtain a score (additive CASUS), or by logistic regression to weight the variables and estimate the probability of mortality (logistic CASUS). Both additive and logistic CASUS have been externally validated elsewhere, but not yet in the United States of America (USA). This study aims to validate CASUS in a quaternary hospital in the USA and compare the predictive performance of additive to logistic CASUS in this setting. Methods Additive and logistic CASUS (postoperative days 1-5) were calculated for 7098 patients at Cleveland Clinic from January 2015 to February 2017. 30-day mortality data were abstracted from institutional records and the Death Registries for Ohio State and the Centers for Disease Control. Given a low event rate, model discrimination was assessed by area under the curve (AUROC), partial AUROC (pAUC), and average precision (AP). Calibration was assessed by curves and quantified using Harrell's Emax, and Integrated Calibration Index (ICI). Results 30-day mortality rate was 1.37%. For additive CASUS, odds ratio for mortality was 1.41 (1.35-1.46, P <0.001). Additive and logistic CASUS had comparable pAUC and AUROC (all >0.83). However, additive CASUS had greater AP, especially on postoperative day 1 (0.22 vs. 0.11). Additive CASUS had better calibration curves, and lower Emax, and ICI on all days. Conclusions Additive and logistic CASUS discriminated well for postoperative 30-day mortality in our quaternary center in the USA, however logistic CASUS under-predicted mortality in our cohort. Given its ease of calculation, and better predictive accuracy, additive CASUS may be the preferred model for postoperative use. Validation in more typical cardiac surgery centers in the USA is recommended.

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