scholarly journals Migration and invasion of oral squamous carcinoma cells is promoted by WNT 5A, a regulator of cancer progression

2014 ◽  
Vol 44 (10) ◽  
pp. 776-784 ◽  
Author(s):  
Zdenka Prgomet ◽  
Lena Axelsson ◽  
Pia Lindberg ◽  
Tommy Andersson
Keyword(s):  
Cancer Progression ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Migration And Invasion ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

scholarly journals The Migration and Invasion of Oral Squamous Carcinoma Cells: Matrix, Growth Factor and Signalling Involvement

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2633
Author(s):  
Ian R. Ellis
Keyword(s):  
Growth Factor ◽  
Cancer Cells ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Migration And Invasion ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

The link between the migration of cancer cells and the spread of cancers has been established for many years [...]

B7-H1 and B7-DC receptors of oral squamous carcinoma cells are upregulated by Porphyromonas gingivalis

Immunobiology ◽  
2011 ◽  
Vol 216 (12) ◽  
pp. 1302-1310 ◽  
Author(s):  
Sabine Groeger ◽  
Eugen Domann ◽  
Jose R. Gonzales ◽  
Trinad Chakraborty ◽  
Joerg Meyle
Keyword(s):  
Porphyromonas Gingivalis ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

scholarly journals Anticancer Effects of Salvia miltiorrhiza Alcohol Extract on Oral Squamous Carcinoma Cells

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Wen-Hung Wang ◽  
Kuo-Yu Hsuan ◽  
Ling-Ya Chu ◽  
Chia-Ying Lee ◽  
Yu-Chang Tyan ◽  
...  
Keyword(s):  
Salvia Miltiorrhiza ◽  
Squamous Carcinoma ◽  
Mitochondrial Pathway ◽  
Carcinoma Cells ◽  
Tumor Xenograft ◽  
Alcohol Extract ◽  
Squamous Carcinoma Cells ◽  
Anticancer Effects ◽  
Oral Squamous Carcinoma

Researchers have reported significant effects from Danshen (Salvia miltiorrhiza) in terms of inhibiting tumor cell proliferation and promoting apoptosis in breast cancer, hepatocellular carcinomas, promyelocytic leukemia, and clear cell ovary carcinomas. Here we report our data indicating that Danshen extracts, especially alcohol extract, significantly inhibited the proliferation of the human oral squamous carcinoma (OSCC) cell lines HSC-3 and OC-2. We also observed that Danshen alcohol extract activated the caspase-3 apoptosis executor by impeding members of the inhibitor of apoptosis (IAP) family, but not by regulating the Bcl-2-triggered mitochondrial pathway in OSCC cells. Our data also indicate that the extract exerted promising effects in vivo, with HSC-3 tumor xenograft growth being suppressed by 40% and 69% following treatment with Danshen alcohol extract at 50 and 100 mg/kg, respectively, for 34 days. Combined, our results indicate appreciable anticancer activity and significant potential for Danshen alcohol extract as a natural antioxidant and herbal human oral cancer chemopreventive drug.

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