scholarly journals The nonlinear association between grandiose and vulnerable narcissism: an individual data meta‐analysis

2021 ◽  
Author(s):  
Emanuel Jauk ◽  
Lisa Ulbrich ◽  
Paul Jorschick ◽  
Michael Höfler ◽  
Scott Barry Kaufman ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Individual Data ◽  
Vulnerable Narcissism ◽  
Nonlinear Association

scholarly journals Individual Data Meta-analysis Provides No Evidence Of Individual Response Variation For Individuals Supplementing With Beta-alanine

2021 ◽  
Vol 53 (8S) ◽  
pp. 282-282
Author(s):  
Gabriel Perri Esteves ◽  
Paul Swinton ◽  
Craig Sale ◽  
Ruth James ◽  
Guilherme Giannini Artioli ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Individual Response ◽  
Individual Data ◽  
Beta Alanine ◽  
Response Variation

scholarly journals Correction to: Epinephrine and short-term survival in cardiogenic shock: an individual data meta-analysis of 2583 patients

2018 ◽  
Vol 44 (11) ◽  
pp. 2022-2023 ◽  
Author(s):  
Valentine Léopold ◽  
Etienne Gayat ◽  
Romain Pirracchio ◽  
Jindrich Spinar ◽  
Jiri Parenica ◽  
...  
Keyword(s):  
Cardiogenic Shock ◽  
Meta Analysis ◽  
Individual Data ◽  
Short Term ◽  
Term Survival ◽  
Short Term Survival

scholarly journals Human Skeletal Muscle has Large Capacity to Increase Carnosine Content in Response to Beta-Alanine Supplementation. A Systematic Review with Bayesian Individual and Aggregate Data E-Max Model and Meta-Analysis

2019 ◽  
Author(s):  
Nathalia Saffioti Rezende ◽  
Paul Swinton ◽  
Luana Farias de Oliveira ◽  
Rafa Pires da Silva ◽  
Vinicius Eira da Silva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skeletal Muscle ◽  
Human Skeletal Muscle ◽  
Meta Analysis ◽  
Aggregate Data ◽  
Individual Data ◽  
Muscle Carnosine ◽  
Large Capacity ◽  
Beta Alanine ◽  
Emax Model

ABSTRACTBeta-alanine (BA) supplementation increases muscle carnosine content (MCarn), and is ergogenic in many situations. Currently, many questions on the nature of the Mcarn response to supplementation are open, and the response to these has considerable potential to enhance the efficacy and applications of this supplementation strategy.ObjectiveTo conduct a Bayesian analysis of available data on the Mcarn response to BA supplementation.MethodsA systematic review with meta-analysis of individual and published aggregate data using a dose response (Emax) model was conducted. The protocol was designed according to PRISMA guidelines. A three-step screening strategy was undertaken to identify studies that measured the Mcarn response to BA supplementation. In addition, individual data from 5 separate studies conducted in the authors’ laboratory were analysed. Data were extracted from all controlled and uncontrolled supplementation studies conducted on healthy humans. Meta-regression was used to consider the influence of potential moderators (including dose, sex, age, baseline Mcarn and analysis method used) on the primary outcome.Results and ConclusionThe Emax model indicated that human skeletal muscle has large capacity for non-linear Mcarn accumulation, and that commonly used BA supplementation protocols may not come close to saturating muscle carnosine content. Neither baseline values, nor sex, appear to influence subsequent response to supplementation. Analysis of individual data indicated that Mcarn is relatively stable in the absence of intervention, and effectually all participants respond to BA supplementation (99.3% response [95%CrI: 96.2 – 100]).

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