scholarly journals Brassinin, a brassica‐derived phytochemical, regulates monocyte‐to‐macrophage differentiation and inflammatory responses in human monocytes and murine macrophages

2020 ◽  
Vol 72 (9) ◽  
pp. 1245-1255
Author(s):  
Bobin Kang ◽  
Jisu Hwang ◽  
Hyeon‐Son Choi
Keyword(s):  
Inflammatory Responses ◽  
Human Monocytes ◽  
Macrophage Differentiation ◽  
Murine Macrophages

scholarly journals Hyperglycemic Memory of Innate Immune Cells Promotes In Vitro Proinflammatory Responses of Human Monocytes and Murine Macrophages

2021 ◽  
pp. ji1901348
Author(s):  
Kathrin Thiem ◽  
Samuel T. Keating ◽  
Mihai G. Netea ◽  
Niels P. Riksen ◽  
Cees J. Tack ◽  
...  
Keyword(s):  
Immune Cells ◽  
Innate Immune ◽  
Innate Immune Cells ◽  
Human Monocytes ◽  
Murine Macrophages ◽  
Proinflammatory Responses

scholarly journals Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages

2018 ◽  
Vol 293 (29) ◽  
pp. 11415-11423 ◽  
Author(s):  
Amy T. Hsu ◽  
Tanya J. Lupancu ◽  
Ming-Chin Lee ◽  
Andrew J. Fleetwood ◽  
Andrew D. Cook ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Human Monocytes ◽  
Murine Macrophages

scholarly journals Modulatory effect of antibiotics on cytokine production by human monocytes in vitro.

1996 ◽  
Vol 40 (6) ◽  
pp. 1366-1370 ◽  
Author(s):  
K Morikawa ◽  
H Watabe ◽  
M Araake ◽  
S Morikawa
Keyword(s):  
Antimicrobial Agents ◽  
Inflammatory Responses ◽  
Interleukin 1 ◽  
Immunomodulatory Activity ◽  
Lymphocyte Function ◽  
Dependent Manner ◽  
Human Monocytes ◽  
Concentration Dependent Manner ◽  
Cytokine Synthesis

Some antimicrobial agents have been reported to modify the host immune and inflammatory responses both in vivo and in vitro. Fosfomycin (FOM) and clarithromycin (CAM) have immunomodulatory activity on human lymphocyte function. In the present study, we examined the effects of FOM and CAM on cytokine synthesis by lipopolysaccharide (LPS)-stimulated human monocytes in comparison with that of dexamethasone in vitro. The three drugs demonstrated positive or negative effects on the synthesis of various cytokines by LPS-primed monocytes. They suppressed the synthesis of tumor necrosis factor alpha, interleukin 1 alpha (IL-1 alpha), IL-1 beta, the IL-1 receptor antagonist, and granulocyte-macrophage colony-stimulating factor in a concentration-dependent manner at concentrations between 1.6 and 40 micrograms/ml. On the contrary, the drugs showed different actions on the synthesis of IL-6 and IL-10. Namely, FOM enhanced both IL-6 and IL-10 synthesis, CAM enhanced only IL-10 synthesis, but dexamethasone deeply suppressed the synthesis of both cytokines. These data indicate that antibacterial agents may modify acute-phase inflammatory responses through their effects on cytokine synthesis by monocytes.

scholarly journals Inhibition of nicotinamide phosphoribosyltransferase modifies LPS-induced inflammatory responses of human monocytes

2011 ◽  
Vol 18 (3) ◽  
pp. 518-530 ◽  
Author(s):  
Erik Schilling ◽  
Janine Wehrhahn ◽  
Carina Klein ◽  
Nora Raulien ◽  
Uta Ceglarek ◽  
...  
Keyword(s):  
Inflammatory Responses ◽  
Human Monocytes ◽  
Nicotinamide Phosphoribosyltransferase

5-Aminosalicylic acid inhibits inflammatory responses by suppressing JNK and p38 activity in murine macrophages

2017 ◽  
Vol 39 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Tingli Qu ◽  
Erbing Wang ◽  
Baofen Jin ◽  
Weiping Li ◽  
Ruiling Liu ◽  
...  
Keyword(s):  
Inflammatory Responses ◽  
Aminosalicylic Acid ◽  
Murine Macrophages
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