scholarly journals Intra‐oral negative pressure therapy upper airway imaging in obstructive sleep apnea patients: responders vs. nonresponders

2019 ◽  
Vol 28 (S1) ◽  
2020 ◽  
Vol 2 (1) ◽  
pp. 35

Among the various sleep-disordered breathing patterns infant’s experience, like periodic breathing, premature apnea, obstructive sleep apnea, has been considered a major cause of concern. Upper airway structure, mechanics of the pulmonary system, etc., are a few reasons why the infants are vulnerable to obstructive sleep-disordered. An imbalance in the viscoelastic properties of the pharynx, dilators, and pressure can lead to airway collapse. A low level of oxygen in blood or hypoxemia is considered a characteristic in infants with severe OSA. Invasive treatments like nasopharyngeal tubes, continuous positive airway pressure (CPAP), or tracheostomy are found to be helpful in most cases where infants experience sleep apnea. This paper proposes an efficient system for monitoring obstructive sleep apnea in infants on a long-term basis, and if any anomaly is detected, the device provides Continuous Airway Pressure therapy until the abnormality is normalized.


Author(s):  
Kevin Motz ◽  
Susheel P. Patil

Obstructive sleep apnea (OSA) is characterized by repeated collapse of the upper airway during sleep that leads to reduced airflow and oxyhemoglobin desaturation. The disorder is highly prevalent, with obesity, male sex, and increasing age as risk factors. Consequences of untreated OSA include neurocognitive impairment, such as excessive daytime sleepiness, and an increased risk of cardiovascular and cerebrovascular disease. Positive airway pressure therapy remains the most common treatment for OSA. Over the last few decades, alternative nonsurgical and surgical treatments have been developed. Although surgical approaches are rarely curative, careful patient selection may benefit a subpopulation of people living with OSA. Selective hypoglossal nerve stimulation represents a new treatment strategy for the management of OSA in selected patients.


1999 ◽  
Vol 86 (6) ◽  
pp. 1759-1763 ◽  
Author(s):  
Lixi Huang ◽  
John E. Ffowcs Williams

The fact that snoring and obstructive apnea only occur during sleep means that effective neuromuscular functioning of the upper airway during sleep is vital for the maintenance of unimpeded breathing. Recent clinical studies in humans have obtained evidence demonstrating that upper airway neural receptors sense the negative pressure generated by inspiration and “trigger,” with a certain delay, reflex muscle activation to sustain the airway that might otherwise collapse. These findings have enabled us to propose a model in which the mechanics is coupled to the neuromuscular physiology through the generation of reflex wall stiffening proportional to the retarded fluid pressure. Preliminary results on this model exhibit three kinds of behavior typical of unimpeded breathing, snoring, and obstructive sleep apnea, respectively. We suggest that the increased latency of the reflex muscle activation in sleep, together with the reduced strength of the reflex, have important clinical consequences.


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