scholarly journals Relating gastric scintigraphy and symptoms to motility capsule transit and pressure findings in suspected gastroparesis

2017 ◽  
Vol 30 (2) ◽  
pp. e13196 ◽  
Author(s):  
W. L. Hasler ◽  
K. P. May ◽  
L. A. Wilson ◽  
M. Van Natta ◽  
H. P. Parkman ◽  
...  
Keyword(s):  
Gastric Scintigraphy

Correlation between symptoms of diabetic gastroparesis and results of gastric scintigraphy

Open Medicine ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Simona Grad ◽  
Laura Poanta ◽  
Dan Dumitrascu ◽  
Mircea Dragoteanu ◽  
Mihai Porojan
Keyword(s):  
Diabetic Gastroparesis ◽  
Gastric Scintigraphy

Abstract

Prokinetic therapy: What can be measured by gastric scintigraphy?

2005 ◽  
Vol 26 (6) ◽  
pp. 527-533 ◽  
Author(s):  
Rainer Linke ◽  
Matthias Meier ◽  
Wolfgang Muenzing ◽  
Christian Folwaczny ◽  
Oliver Schnell ◽  
...  
Keyword(s):  
Gastric Scintigraphy ◽  
Prokinetic Therapy

Differences in intragastric pH in diabetic vs. idiopathic gastroparesis: relation to degree of gastric retention

2008 ◽  
Vol 294 (6) ◽  
pp. G1384-G1391 ◽  
Author(s):  
William L. Hasler ◽  
Radoslav Coleski ◽  
William D. Chey ◽  
Kenneth L. Koch ◽  
Richard W. McCallum ◽  
...  
Keyword(s):  
Gastric Acid ◽  
Gastric Ph ◽  
Diabetic Patients ◽  
Gastric Retention ◽  
Gastric Stasis ◽  
Control Subjects ◽  
Idiopathic Gastroparesis ◽  
Initial Ph ◽  
Gastric Scintigraphy ◽  
Ph Profiles

Evidence suggests that distinct mechanisms underlie diabetic and idiopathic gastroparesis. Differences in gastric acid in gastroparesis of different etiologies and varying degrees of gastric stasis are uninvestigated. We tested the hypotheses that 1) gastric pH profiles show differential alteration in diabetic vs. idiopathic gastroparesis and 2) abnormal pH profiles relate to the severity of gastric stasis. Sixty-four healthy control subjects and 44 gastroparesis patients (20 diabetic, 24 idiopathic) swallowed wireless transmitting capsules and then consumed99mTc-sulfur colloid-labeled meals for gastric scintigraphy. Gastric pH from the capsule was recorded every 5 s. Basal pH was higher in diabetic (3.64 ± 0.41) vs. control subjects (1.90 ± 0.18) and idiopathic subjects (2.41 ± 0.42; P < 0.05). Meals evoked initial pH increases that were greater in diabetic (4.98 ± 0.32) than idiopathic patients (3.89 ± 0.39; P = 0.03) but not control subjects (4.48 ± 0.14). pH nadirs prior to gastric capsule evacuation were higher in diabetic patients (1.50 ± 0.23) than control subjects (0.58 ± 0.11; P = 0.003). Four-hour gastric retention was similar in diabetic (18.3 ± 0.5%) and idiopathic (19.4 ± 0.5%) patients but higher than control subjects (2.2 ± 0.5%; P < 0.001). Compared with control subjects, those with moderate-severe stasis (>20% retention at 4 h) had higher basal (3.91 ± 0.55) and nadir pH (2.23 ± 0.42) values ( P < 0.05). In subgroup analyses, both diabetic and idiopathic patients with moderate-severe gastroparesis exhibited increased pH parameters vs. those with mild gastroparesis. In conclusion, diabetic patients with gastroparesis exhibit reduced gastric acid, an effect more pronounced in those with severely delayed gastric emptying. Idiopathic gastroparetic subjects exhibit nearly normal acid profiles, although those with severely delayed emptying show reduced acid vs. those with mild delays. Thus both etiology and degree of gastric stasis determine gastric acidity in gastroparesis.

Impact of methodical guidelines of gastric scintigraphy on patients’ radiation exposure

2021 ◽  
Vol 75 (2) ◽  
pp. 159-164
Author(s):  
Martina Horváthová ◽  
Zuzana Bárdyová ◽  
Darina Budošová ◽  
Rastislav Husťak
Keyword(s):  
Gastric Emptying ◽  
Radiation Exposure ◽  
Gold Standard ◽  
Retrospective Cohort ◽  
Noninvasive Method ◽  
Lower Intensity ◽  
Medicine Department ◽  
Nuclear Medicine Department ◽  
Gastric Emptying Scintigraphy ◽  
Gastric Scintigraphy

Introduction: Gastric emptying scintigraphy (GES) is a safe, noninvasive method for assessing the ability of the stomach to empty which has been used clinically for many years. It is considered as a “gold standard” to assess gastric emptying of both solids and liquids allowing assessment of early, mid and late emptying, each of which may be altered by pathology. The aim of the study was to analyse standard diagnostic approach and evaluate patients` radiation exposure, who underwent GES in Slovakia. Methods: A retrospective cohort study included 55 patients from 2 departments of nuclear medicine (department A, B). Patients’ radiation exposure was determined by dosimetry program IDAC-Dose2.1. The radiopharmaceutical 99mTc-DTPA, always with the same activity, was applied orally to patients at Department B. The applied activity of the radiopharmaceutical at GES was 185 MBq. The radiopharmaceutical 99mTc MAA, with various activity, was applied orally to patients at Department A. Results: According to ICRP60, the eff ective dose (ED) of every patient undergoing GES was 0.77 mSv and, according to ICRP103, the dose was 0.836 mSv at Department B. Patients at Department A were exposed to ionizing radiation with 5-times lower intensity, compared with patients at Department B. It was caused by radiopharmaceutical activity correction. The ED medians according to ICRP60, and according to ICRP103 were 0.167 mSv (range 0.105–0.208 mSv) and 0.181 mSv (range 0.113–0.226 mSv) at Department A, respectively. Discussion: Adequate correction of applied radiopharmaceutical activity is an essential part of GES guidelines and in accordance with ALARA principles. For the accuracy of GES examination, it is necessary to follow a standard 4-hour protocol and an approach which ensures full-featured utilization of the examination while decreasing patient`s radiation exposure. Conclusion: The results of our study show relatively low ED associated with GES, but also confi rm that the GES methodology significantly affects the patient`s radiation exposure

scholarly journals PWE-049 Effects of age, sex and obesity on satiation assessed by nutrient drink test and gastric emptying (GE) assessed by non-invasive gastric scintigraphy (GS) and MRI: analysis and comparison of methods

Gut ◽  
2012 ◽  
Vol 61 (Suppl 2) ◽  
pp. A316.2-A317
Author(s):  
H Parker ◽  
C Hoad ◽  
N Hudders ◽  
E Tucker ◽  
A Perkins ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Comparison Of Methods ◽  
Non Invasive ◽  
Gastric Scintigraphy ◽  
Drink Test

Discordant Emptying From Hiatal Hernia and Stomach With Severe Esophageal Reflux Demonstrated by Gastric Scintigraphy

2010 ◽  
Vol 35 (3) ◽  
pp. 187-188 ◽  
Author(s):  
Michael E. Witkosky ◽  
Alan D. Waxman
Keyword(s):  
Hiatal Hernia ◽  
Esophageal Reflux ◽  
Gastric Scintigraphy

American consensus recommendations for gastric scintigraphy

2011 ◽  
Vol 32 (1) ◽  
pp. 30-36 ◽  
Author(s):  
Pierre-Yves Le Roux ◽  
Francis Bouchet ◽  
Solène Querellou ◽  
Laurent Vervueren ◽  
Franck Lacoeuille ◽  
...  
Keyword(s):  
Consensus Recommendations ◽  
Gastric Scintigraphy

Objective assessment of delayed gastric emptying using gastric scintigraphy in post pancreaticoduodenectomy patients

2015 ◽  
Vol 87 (9) ◽  
pp. E80-E84 ◽  
Author(s):  
Avishek Samaddar ◽  
Lileswar Kaman ◽  
Divya Dahiya ◽  
Anish Bhattachyarya ◽  
Saroj Kant Sinha
Keyword(s):  
Gastric Emptying ◽  
Delayed Gastric Emptying ◽  
Objective Assessment ◽  
Gastric Scintigraphy

scholarly journals Abnormal gastric scintigraphy is not a reliable sign of diabetic autonomic neuropathy

1993 ◽  
Vol 10 (5) ◽  
pp. 193-196
Author(s):  
H Nilsson ◽  
B Lilja ◽  
I Rosén ◽  
O Ekberg ◽  
G Sundkvist
Keyword(s):  
Autonomic Neuropathy ◽  
Diabetic Autonomic Neuropathy ◽  
Gastric Scintigraphy ◽  
Reliable Sign

scholarly journals Gastroparesis

2020 ◽  
Vol 95 (4) ◽  
pp. 244-250
Author(s):  
Li-Chang Hsing ◽  
Kee Wook Jung
Keyword(s):  
Diabetes Mellitus ◽  
Abdominal Pain ◽  
Gastric Emptying ◽  
Nutritional Support ◽  
Delayed Gastric Emptying ◽  
Mechanical Obstruction ◽  
Upper Endoscopy ◽  
Pharmacological Treatments ◽  
Contrast Radiography ◽  
Gastric Scintigraphy

Gastroparesis is a condition characterized by delayed gastric emptying without evidence of mechanical obstruction in the stomach. Its symptoms include nausea, vomiting, early satiety, abdominal bloating, and abdominal pain. Most cases of gastroparesis are either idiopathic, due to diabetes mellitus, or post-surgical complications. The diagnosis of gastroparesis requires upper endoscopy, contrast radiography, or validated gastric scintigraphy. Gastroparesis is managed with nutritional support and treatment of any underlying disorders, such as diabetes. Pharmacological treatments have been tried, including prokinetics and novel medications. Interventions focused on the pylorus have shown promising results.

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