Impact of methodical guidelines of gastric scintigraphy on patients’ radiation exposure

Introduction: Gastric emptying scintigraphy (GES) is a safe, noninvasive method for assessing the ability of the stomach to empty which has been used clinically for many years. It is considered as a “gold standard” to assess gastric emptying of both solids and liquids allowing assessment of early, mid and late emptying, each of which may be altered by pathology. The aim of the study was to analyse standard diagnostic approach and evaluate patients` radiation exposure, who underwent GES in Slovakia. Methods: A retrospective cohort study included 55 patients from 2 departments of nuclear medicine (department A, B). Patients’ radiation exposure was determined by dosimetry program IDAC-Dose2.1. The radiopharmaceutical 99mTc-DTPA, always with the same activity, was applied orally to patients at Department B. The applied activity of the radiopharmaceutical at GES was 185 MBq. The radiopharmaceutical 99mTc MAA, with various activity, was applied orally to patients at Department A. Results: According to ICRP60, the eff ective dose (ED) of every patient undergoing GES was 0.77 mSv and, according to ICRP103, the dose was 0.836 mSv at Department B. Patients at Department A were exposed to ionizing radiation with 5-times lower intensity, compared with patients at Department B. It was caused by radiopharmaceutical activity correction. The ED medians according to ICRP60, and according to ICRP103 were 0.167 mSv (range 0.105–0.208 mSv) and 0.181 mSv (range 0.113–0.226 mSv) at Department A, respectively. Discussion: Adequate correction of applied radiopharmaceutical activity is an essential part of GES guidelines and in accordance with ALARA principles. For the accuracy of GES examination, it is necessary to follow a standard 4-hour protocol and an approach which ensures full-featured utilization of the examination while decreasing patient`s radiation exposure. Conclusion: The results of our study show relatively low ED associated with GES, but also confi rm that the GES methodology significantly affects the patient`s radiation exposure

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[OA203] Assessment of radiation exposure in a newly formed nuclear medicine department

Physica Medica ◽

10.1016/j.ejmp.2018.06.275 ◽

2018 ◽

Vol 52 ◽

pp. 78

Author(s):

Panayiotis Hadjitheodorou ◽

Irene Polycarpou ◽

Andreas Fesas ◽

Reza Pourkhessalian ◽

Alexis Vrachimis ◽

...

Keyword(s):

Nuclear Medicine ◽

Radiation Exposure ◽

Medicine Department ◽

Nuclear Medicine Department

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Delayed absorption of many (paracetamol, aspirin, other NSAIDs and zolmitriptan) but not all (sumatriptan, rizatriptan) drugs during migraine attacks and most likely normal gastric emptying outside attacks. A review

Cephalalgia ◽

10.1177/0333102416644745 ◽

2016 ◽

Vol 37 (9) ◽

pp. 892-901 ◽

Cited By ~ 1

Author(s):

Peer Carsten Tfelt-Hansen

Keyword(s):

Gastric Emptying ◽

Oral Absorption ◽

Clinical Implications ◽

Pharmacokinetic Studies ◽

Gastric Stasis ◽

Gastric Emptying Scintigraphy ◽

Antiemetic Drugs ◽

Proven Efficacy ◽

Gastric Scintigraphy ◽

Therapeutic Doses

Background In most pharmacokinetic studies, the oral absorption of drugs is impaired during migraine attacks but exceptions occur. A study on gastric emptying using gastric scintigraphy indicated that gastric stasis also occurs interictally in migraine. These studies were reviewed critically. Results In seven studies, mainly investigating NSAIDs and analgesics, the early absorption of the drugs during 112 migraine attacks was delayed. The absorption of sumatriptan is usual in therapeutic doses, and rizatriptan was normal during 131 migraine attacks. The interictal gastric stasis observed using gastric emptying scintigraphy (GES) with solids ( n = 13) could not be confirmed in a larger study ( n = 27) using the same method. Also gastric emptying measured with GES with liquids ( n = 7) and epigastric impedance ( n = 64) was normal outside migraine attacks. Conclusions and possible clinical implications Drug absorption is not generally impaired during migraine attacks. Gastric emptying is most likely normal in the majority of migraine patients outside attacks. Prokinetic and antiemetic drugs such as metoclopramide and domperidone should not be routinely combined with oral analgesics or oral triptans. If, however, nausea is severe or vomiting occurs, treatment with an antiemetic with proven efficacy on the nausea of migraine can be indicated.

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Annual Radiation Exposure to Workers in a Tertiary Care Hospital in Kashmir : A 10-Year Analysis and Comparison with National Levels of exposure

JMS SKIMS ◽

10.33883/jms.v12i2.191 ◽

2009 ◽

Vol 12 (2) ◽

pp. 41-45

Author(s):

Tanveer A Rather ◽

Showkat H Khan ◽

Mohib Ul Haq ◽

Riyaz A Rangrez ◽

Ajaz Mustafa

Keyword(s):

Radiation Exposure ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Whole Body ◽

Care Hospital ◽

Medical Sciences ◽

Annual Dose ◽

Medicine Department ◽

Nuclear Medicine Department ◽

Radiation Workers

Objective: To assess the radiation exposure amongst radiation workers in Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, a tertiary care 620 bedded superspeciality hospital was carried out. Material and Methods: A 10-year retrospective analysis of the whole body radiation exposure to the radiation workers of SKIMS Srinagar, Two blocks of five years each from 1995 to 1999 & 2002 to 2007 were studied and compared with the national pool of radiation workers for the same period. The average annual dose of radiation workers working in different radiation departments of SKIMS was compared with the workers of the similar department of the national pool. Results & Conclusion: It was observed that in the block of 5 years from 1995 to 1999 the average whole body dose to the radiation works at SKIMS during the latter half showed a rising trend for three years as compared to the national pool. However in the block 2002 to 2005 the average annual dose was mostly similar except for a higher dose to SKIMS workers in 2005. It was observed that the average annual dose received by the workers of Nuclear Medicine department of SKIMS was usually high more so in the five year block of 2000 to 2005.The workers of Radiodiagnosis at SKIMS also received a higher annual dose in 7 of the 10 years of study. J Med Sci 2009;12(2):41-45

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