One ring to rule them all? Genome sequencing provides new insights into the ‘master circle’ model of plant mitochondrial DNA structure

2013 ◽  
Vol 200 (4) ◽  
pp. 978-985 ◽  
Author(s):  
Daniel B. Sloan
Keyword(s):  
Mitochondrial Dna ◽  
Genome Sequencing ◽  
Dna Structure ◽  
Plant Mitochondrial Dna ◽  
Circle Model

scholarly journals Comparison of whole genome sequencing and targeted sequencing for Mitochondrial DNA

Mitochondrion ◽  
2021 ◽  
Author(s):  
Ruoying Chen ◽  
Micheala A Aldred ◽  
Weiling Xu ◽  
Joe Zein ◽  
Peter Bazeley ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Targeted Sequencing ◽  
Whole Genome

scholarly journals Norgal: extraction and de novo assembly of mitochondrial DNA from whole-genome sequencing data

2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Kosai Al-Nakeeb ◽  
Thomas Nordahl Petersen ◽  
Thomas Sicheritz-Pontén
Keyword(s):  
Mitochondrial Dna ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
De Novo Assembly ◽  
De Novo ◽  
Whole Genome Sequencing Data ◽  
Whole Genome ◽  
Sequencing Data

Rare instances of non-random dropout with the monochrome multiplex qPCR assay for mitochondrial DNA copy number

2021 ◽  
Author(s):  
Stephanie Y Yang ◽  
Charles E Newcomb ◽  
Stephanie L Battle ◽  
Anthony YY Hsieh ◽  
Hailey L Chapman ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Copy Number ◽  
Whole Genome Sequencing Data ◽  
Whole Genome ◽  
Dna Copy Number ◽  
Loop Primer ◽  
Mitochondrial Dna Copy Number ◽  
D Loop

Mitochondrial DNA copy number (mtDNA-CN) is a proxy for mitochondrial function and has been of increasing interest to the mitochondrial research community. There are several ways to measure mtDNA-CN, ranging from whole genome sequencing to qPCR. A recent article from the Journal of Molecular Diagnostics described a novel method for measuring mtDNA-CN that is both inexpensive and reproducible. However, we show that certain individuals, particularly those with very low qPCR mtDNA measurements, show poor concordance between qPCR and whole genome sequencing measurements. After examining whole genome sequencing data, this seems to be due to polymorphisms within the D-loop primer region. Non-concordant mtDNA-CN was observed in all instances of polymorphisms at certain positions in the D-loop primer regions, however, not all positions are susceptible to this effect. In particular, these polymorphisms appear disproportionately in individuals with the L, T, and U mitochondrial haplogroups, indicating non-random dropout.

Mitochondrial DNA structure and function

2002 ◽  
pp. 3-23 ◽  
Author(s):  
Carlos T. Moraes ◽  
Sarika Srivastava ◽  
Ilias Kirkinezos ◽  
Jose Oca-Cossio ◽  
Corina vanWaveren ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Dna Structure ◽  
Structure And Function ◽  
And Function

The main regulatory region of mammalian mitochondrial DNA: Structure-function model and evolutionary pattern

1991 ◽  
Vol 33 (1) ◽  
pp. 83-91 ◽  
Author(s):  
Cecilia Saccone ◽  
Graziano Pesole ◽  
Elisabetta Sbisá
Keyword(s):  
Mitochondrial Dna ◽  
Structure Function ◽  
Regulatory Region ◽  
Dna Structure ◽  
Function Model ◽  
Evolutionary Pattern

Interorganellar sequence transfer: Plant mitochondrial DNA is nuclear, is plastid, is mitochondrial

Plant Science ◽  
1988 ◽  
Vol 54 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Wolfgang Schuster ◽  
Axel Brennicke
Keyword(s):  
Mitochondrial Dna ◽  
Plant Mitochondrial Dna

Interaction of polyribonucleotides with plant mitochondrial DNA

1973 ◽  
Vol 54 (4) ◽  
pp. 1326-1334 ◽  
Author(s):  
Francis Quetier ◽  
Fernand Vedel
Keyword(s):  
Mitochondrial Dna ◽  
Plant Mitochondrial Dna
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