Diagnostic performance of 2D‐shear wave elastography and serum fibrosis markers for evaluation of hepatic graft fibrosis in pediatric liver‐inclusive transplant recipients: A prospective pilot study

2022 ◽  
Author(s):  
Hanh D. Vo ◽  
Stanley J. Radio ◽  
Elon J. Granader ◽  
Laura E. Wojkiewicz ◽  
Patricia Turner ◽  
...  
Keyword(s):  
Pilot Study ◽  
Shear Wave ◽  
Diagnostic Performance ◽  
Shear Wave Elastography ◽  
Transplant Recipients ◽  
Prospective Pilot Study ◽  
Pediatric Liver

Utility of Shear Wave Elastography for Assessing Allograft Fibrosis in Renal Transplant Recipients: A Pilot Study

2017 ◽  
Vol 37 (6) ◽  
pp. 1455-1465 ◽  
Author(s):  
Heather M. Early ◽  
Ellen C. Cheang ◽  
Jorge M. Aguilera ◽  
Jonah S. W. Hirschbein ◽  
Ghaneh Fananapazir ◽  
...  
Keyword(s):  
Pilot Study ◽  
Renal Transplant ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Renal Transplant Recipients ◽  
Transplant Recipients

Assessment of Fibrosis in Liver Transplant Recipients: Diagnostic Performance of Shear Wave Elastography (SWE) and Correlation of SWE Findings With Biopsy Results

2019 ◽  
Vol 213 (6) ◽  
pp. W264-W271 ◽  
Author(s):  
Corinne Deurdulian ◽  
Edward G. Grant ◽  
Hisham Tchelepi ◽  
Paul T. Latterman ◽  
Jeremy T. Paluch ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Shear Wave ◽  
Diagnostic Performance ◽  
Shear Wave Elastography ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

scholarly journals Transvaginal Ultrasound Shear Wave Elastography for the Evaluation of Benign Uterine Pathologies: A Prospective Pilot Study

2018 ◽  
Vol 38 (1) ◽  
pp. 149-155 ◽  
Author(s):  
Man Zhang ◽  
Ashish P. Wasnik ◽  
William R. Masch ◽  
Jonathan M. Rubin ◽  
Ruth C. Carlos ◽  
...  
Keyword(s):  
Pilot Study ◽  
Shear Wave ◽  
Transvaginal Ultrasound ◽  
Shear Wave Elastography ◽  
Prospective Pilot Study

Prospective assessment of liver stiffness by shear wave elastography in childhood obesity: a pilot study

Endocrine ◽  
2021 ◽  
Author(s):  
Domenico Corica ◽  
Antonio Bottari ◽  
Tommaso Aversa ◽  
Letteria Anna Morabito ◽  
Selenia Curatola ◽  
...  
Keyword(s):  
Childhood Obesity ◽  
Pilot Study ◽  
Shear Wave ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Prospective Assessment

Ultrasound Shear Wave Elastography as a Measure of Porcine Hepatic Disease in Right Heart Dysfunction: A Pilot Study

2018 ◽  
Vol 44 (11) ◽  
pp. 2393-2399 ◽  
Author(s):  
Jessie J. Hu ◽  
M. Yasir Qureshi ◽  
Matthew W. Urban ◽  
Rondell Graham ◽  
Meng Yin ◽  
...  
Keyword(s):  
Pilot Study ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Hepatic Disease ◽  
Right Heart ◽  
Heart Dysfunction ◽  
Right Heart Dysfunction

scholarly journals Accuracy of shear wave elastography in characterization of thyroid nodules in children and adolescents

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Mohammed Hazem ◽  
Ossama M. Zakaria ◽  
Mohamed Yasser Ibrahim Daoud ◽  
Ibrahim Khalid Al Jabr ◽  
Abdulwahab A. AlYahya ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Shear Wave ◽  
Diagnostic Performance ◽  
Thyroid Nodules ◽  
Shear Wave Elastography ◽  
Invasive Technique ◽  
Predictive Values ◽  
Patients Âgés ◽  
Non Invasive

Abstract Background Thyroid nodules are an important health problem in children and adolescents. They possess a higher risk of malignancy in comparison to adults. This fact forms a great dilemma for clinicians. The aim of this study was to evaluate the reliability of shear wave elastography (SWE) as a non-invasive technique in the characterization of thyroid nodules in children and adolescents. Methods This prospective study included 56 patients with thyroid nodules. All the patients underwent clinical assessment, laboratory investigations, ultrasound, and Doppler examination, followed by an SWE assessment. Statistical analysis was performed and the best cut-off value to differentiate benign from malignant nodules was determined using the ROC curve and AUC. Results Seventy-two nodules were detected in the examined patients (ages ranged from 11 to 19 years, with mean age of 14.89 ± 2.3 years). Fifty-eight nodules (80.6%) were benign, and fourteen nodules (19.4%) were malignant (histopathologically proved). Highly suspicious criteria for prediction of malignancy by ultrasound and Doppler were hypoechoic echopattern, internal or internal and peripheral vascularity, microcalcifications, taller-than-wide dimensions, irregular outlines, and absence of halo (p < 0.05). The diagnostic performance for their summation was 70.69% sensitivity, 82.8% specificity, 80.45% accuracy, a 63.79% positive predictive value (PPV), and 87.9% negative predictive values (NPV). Regarding SWE, our results showed that 42.2 kPa was the best cut-off value, with AUC = 0.921 to differentiate malignant from benign nodules; the diagnostic performance was 85.71% sensitivity, 94.83% specificity, 93.06% accuracy, 76.9% PPV, and 93.2% NPV. Conclusion Shear wave elastography is a non-invasive technique that can assist in the diagnosis of malignant thyroid nodules among children and adolescents.

scholarly journals Diagnostic Performance of Two-dimensional Shear Wave Elastography in Advanced Liver Fibrosis: A Prospective Pathology-based Study

2020 ◽  
Author(s):  
Yao-Kuang Huang ◽  
Ren-Ching Wang ◽  
Sheng-Shun Yang ◽  
Shou-Wu Lee ◽  
Hsin-Ju Tsai ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Shear Wave ◽  
Liver Diseases ◽  
Diagnostic Performance ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Liver Disorders ◽  
Advanced Liver Fibrosis ◽  
Invasive Method

Abstract Studies for evaluating the diagnostic performance of two-dimensional Shear-wave Elastography (2D-SWE) in a patient cohort including various liver disorders, remain limited. We aimed to evaluate the validity of 2D-SWE in the diagnosis of advanced liver fibrosis amongst patients with various liver disorders. In this pathology-based study, patients who underwent a liver biopsy for various benign liver diseases were prospectively recruited during the period between February, 2017 and September, 2020. Data of 2D-SWE, Fibrosis-4 Index (FIB-4), and Aspartate Aminotransferase to Platelet Ratio Index (APRI) were simultaneously collected. The cut-off values for predicting advanced fibrosis, i.e. Metavir fibrosis stage ≥ F3, were determined using Receiver Operating Characteristic (ROC) analysis. The diagnostic performance was evaluated and then compared by Area Under the ROC (AUROC). In total, 95 patients were recruited for study analysis. The diagnostic performance of 2D-SWE was significantly superior to that of both FIB-4 (AUROC: 0.88, 95% confidence interval [CI]: 0.80-0.94; vs 0.72, 95%CI: 0.62-0.81; p=0.001) and APRI (AUROC: 0.88, 95%CI: 80-0.94; vs 0.76, 95%CI: 0.66-0.84; p=0.007). With an optimal cutoff value of 9.3 kPa, the sensitivity and specificity were 90.91% and 76.47%, respectively. In subgroup analysis, the AUROC of 2D-SWE was the highest when compared to that of FIB-4 and APRI in patients with chronic hepatitis B, chronic hepatitis C, fatty liver, and concurrent hepatitis. 2D-SWE can therefore be a valid non-invasive method in the detection of advanced liver fibrosis in various liver diseases.

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