Association between quality of life and sun exposure behaviour in patients treated for cutaneous malignant melanoma

2019 ◽  
Author(s):  
Luise Winkel Idorn ◽  
Pameli Datta ◽  
Jakob Heydenreich ◽  
Peter Alshede Philipsen ◽  
Hans Christian Olsen Wulf
Keyword(s):  
Quality Of Life ◽  
Malignant Melanoma ◽  
Sun Exposure ◽  
Cutaneous Malignant Melanoma

scholarly journals TRIM study protocol - a prospective randomized multicenter Trial to assess the Role of Imaging during follow-up after radical surgery of stage IIB-C and III cutaneous malignant Melanoma

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Ylva Naeser ◽  
Hildur Helgadottir ◽  
Yvonne Brandberg ◽  
Johan Hansson ◽  
Roger Olofsson Bagge ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Risk ◽  
Malignant Melanoma ◽  
Potential Benefit ◽  
Radical Surgery ◽  
Multicenter Trial ◽  
Cutaneous Malignant Melanoma ◽  
Link Type

Abstract Background The incidence of cutaneous malignant melanoma (CMM) is increasing worldwide. In Sweden, over 4600 cases were diagnosed in 2018. The prognosis after radical surgery varies considerably with tumor stage. In recent years, new treatment options have become available for metastatic CMM. Early onset of treatment seems to improve outcome, which suggests that early detection of recurrent disease should be beneficial. Consequently, in several countries imaging is a part of the routine follow-up program after surgery of high risk CMM. However, imaging has drawbacks, including resources required (costs, personnel, equipment) and the radiation exposure. Furthermore, many patients experience anxiety in waiting for the imaging results and investigations of irrelevant findings is another factor that also could cause worry and lead to decreased quality of life. Hence, the impact of imaging in this setting is important to address and no randomized study has previously been conducted. The Swedish national guidelines stipulate follow-up for 3 years by clinical examinations only. Methods The TRIM study is a prospective randomized multicenter trial evaluating the potential benefit of imaging and blood tests during follow-up after radical surgery for high-risk CMM, compared to clinical examinations only. Primary endpoint is overall survival (OS) at 5 years. Secondary endpoints are survival from diagnosis of relapse and health-related quality of life (HRQoL). Eligible for inclusion are patients radically operated for CMM stage IIB-C or III with sufficient renal function for iv contrast-enhanced CT and who are expected to be fit for treatment in case of recurrence. The planned number of patients is > 1300. Patients are randomized to clinical examinations for 3 years +/− whole-body imaging with CT or FDG-PET/CT and laboratory tests including S100B protein and LDH. This academic study is supported by the Swedish Melanoma Study Group. Discussion This is the first randomized prospective trial on the potential benefit of imaging as a part of the follow-up scheme after radical surgery for high-risk CMM. Results The first patient was recruited in June 2017 and as of April 2020, almost 500 patients had been included at 19 centers in Sweden. Trial registration ClinicalTrials.gov, NCT 03116412. Registered 17 April 2017, https://clinicaltrials.gov/ct2/show/study/NCT03116412

scholarly journals Advanced Cutaneous Malignant Melanoma: A Systematic Review of Economic and Quality-of-Life Studies

2008 ◽  
Vol 11 (2) ◽  
pp. 259-271 ◽  
Author(s):  
Richard P. Cashin ◽  
Philip Lui ◽  
Márcio Machado ◽  
Michiel E.H. Hemels ◽  
Patricia K. Corey-Lisle ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Malignant Melanoma ◽  
Cutaneous Malignant Melanoma

scholarly journals PCN63 ADVANCED CUTANEOUS MALIGNANT MELANOMA: SYSTEMATIC REVIEW OF PHARMACOECONOMIC AND QUALITY OF LIFE STUDIES

2006 ◽  
Vol 9 (6) ◽  
pp. A295 ◽  
Author(s):  
M Machado ◽  
R Cashin ◽  
P Lui ◽  
M Hemels ◽  
P Corey-Lisle ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Malignant Melanoma ◽  
Cutaneous Malignant Melanoma

Quality of life in patients with malignant melanoma participating in a phase I trial of an autologous tumour-derived vaccine

2002 ◽  
Vol 12 (5) ◽  
pp. 505-511 ◽  
Author(s):  
L. Cohen ◽  
P. A. Parker ◽  
J. Sterner ◽  
C. de Moor
Keyword(s):  
Quality Of Life ◽  
Malignant Melanoma ◽  
Phase I ◽  
Phase I Trial ◽  
Autologous Tumour

Cutaneous Malignant Melanoma in Women. Phenotypic Characteristics, Sun Exposure, and Hormonal Factors: A Case–Control Study from Italy

2005 ◽  
Vol 15 (7) ◽  
pp. 545-550 ◽  
Author(s):  
Luigi Naldi ◽  
Andrea Altieri ◽  
Gian Lorenzo Imberti ◽  
Laura Giordano ◽  
Silvano Gallus ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Case Control Study ◽  
Sun Exposure ◽  
Case Control ◽  
Cutaneous Malignant Melanoma ◽  
Phenotypic Characteristics ◽  
Hormonal Factors ◽  
Control Study

Cutaneous malignant melanoma, sun exposure, and sunscreen use: epidemiological evidence

2002 ◽  
Vol 146 (s61) ◽  
pp. 24-30 ◽  
Author(s):  
S. Bastuji-Garin ◽  
T.L. Diepgen
Keyword(s):  
Malignant Melanoma ◽  
Sun Exposure ◽  
Cutaneous Malignant Melanoma ◽  
Epidemiological Evidence ◽  
Sunscreen Use

scholarly journals Quality of life Evaluation by the eortc Questionnaire Technique in Patients with Generalized Malignant Melanoma on Chemotherapy

1996 ◽  
Vol 35 (2) ◽  
pp. 149-158 ◽  
Author(s):  
Valgerdur Sigurdardöttir ◽  
Christina Bolund And ◽  
Marianne Sullivan
Keyword(s):  
Quality Of Life ◽  
Malignant Melanoma ◽  
Life Evaluation

scholarly journals How I treat acne scars?

2021 ◽  
Vol 1 ◽  
pp. 39
Author(s):  
Rasya Dixit
Keyword(s):  
Quality Of Life ◽  
Sun Exposure ◽  
Patient Expectations ◽  
Skin Hydration ◽  
Exposure Age ◽  
Acne Scars ◽  
Negative Effect ◽  
Acne Treatment ◽  
Multiple Treatments

Acne scars affect up to 95% of those suffering from acne and have a significant negative effect on quality of life. It is imperative to complete acne treatment before scar treatment commences. The treatment of the scars begins with the analysis of the skin type, scar type, lifestyle, and sun exposure. Age of the patient, patient expectations, timelines, and budget are important considerations. Treatment of the scars includes release of the subdermal bands with subcision, improvement of the neocollagenosis by causing regular thermal or mechanical microinjury to the dermis, improvement of epidermal pigment, and improvement of skin hydration. Often, multiple treatments and multimodality treatments need to be used to give satisfactory results.

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