scholarly journals Dynamic changes in mitochondrial DNA, distribution and activity within cat oocytes during folliculogenesis

2017 ◽  
Vol 52 ◽  
pp. 71-76 ◽  
Author(s):  
N Songsasen ◽  
LH Henson ◽  
W Tipkantha ◽  
C Thongkittidilok ◽  
JH Henson ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Dynamic Changes ◽  
Dna Distribution

Dynamic changes in mitochondrial DNA, morphology, and fission during oogenesis of a seasonal-breeding teleost, Pampus argenteus

2021 ◽  
pp. 101558
Author(s):  
Yang Yang ◽  
Chao Ning ◽  
Yaya Li ◽  
Yajun Wang ◽  
Jiabao Hu ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Seasonal Breeding ◽  
Dynamic Changes ◽  
Pampus Argenteus

Dynamic Changes of Mitochondrial DNA Copy Number in Gastrointestinal Tract Cancers: A Systematic Review and Meta-analysis

2020 ◽  
pp. 1-35
Author(s):  
Mehdi Alikhani ◽  
Eliette Touati ◽  
Morteza Karimipoor ◽  
Massoud Vosough ◽  
Sana Eybpoosh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mitochondrial Dna ◽  
Gastrointestinal Tract ◽  
Copy Number ◽  
Meta Analysis ◽  
Dna Copy Number ◽  
Dynamic Changes ◽  
Mitochondrial Dna Copy Number

scholarly journals Mitochondrial DNA: Distribution, Mutations, and Elimination

Cells ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 379 ◽  
Author(s):  
Yan ◽  
Duanmu ◽  
Zeng ◽  
Liu ◽  
Song
Keyword(s):  
Mitochondrial Dna ◽  
Mitochondrial Matrix ◽  
Endonuclease G ◽  
Respiratory Complexes ◽  
Dna Distribution ◽  
Mitochondrial Functions ◽  
Mitochondrial Respiratory

Mitochondrion harbors its own DNA (mtDNA), which encodes many critical proteins for the assembly and activity of mitochondrial respiratory complexes. mtDNA is packed by many proteins to form a nucleoid that uniformly distributes within the mitochondrial matrix, which is essential for mitochondrial functions. Defects or mutations of mtDNA result in a range of diseases. Damaged mtDNA could be eliminated by mitophagy, and all paternal mtDNA are degraded by endonuclease G or mitophagy during fertilization. In this review, we describe the role and mechanism of mtDNA distribution and elimination. In particular, we focus on the regulation of paternal mtDNA elimination in the process of fertilization.

Dynamic changes of deleted mitochondrial DNA in human leucocytes after endurance exercise

2003 ◽  
Vol 88 (6) ◽  
pp. 515-519 ◽  
Author(s):  
Koichi Iwai ◽  
Masahiko Miyao ◽  
Yasuyoshi Wadano ◽  
Yukio Iwamura
Keyword(s):  
Mitochondrial Dna ◽  
Endurance Exercise ◽  
Dynamic Changes

Evaluation of the dark field method for large association of spread DNA

1978 ◽  
Vol 36 (2) ◽  
pp. 190-191
Author(s):  
Douglas C. Barker
Keyword(s):  
Electron Microscopy ◽  
Molecular Weight ◽  
Mitochondrial Dna ◽  
Extraction Method ◽  
Field Method ◽  
Dark Field ◽  
Kinetoplast Dna ◽  
Field Electron ◽  
Field Electron Microscopy ◽  
Dark Field Electron

A number of satisfactory methods are available for the electron microscopy of nicleic acids. These methods concentrated on fragments of nuclear, viral and mitochondrial DNA less than 50 megadaltons, on denaturation and heteroduplex mapping (Davies et al 1971) or on the interaction between proteins and DNA (Brack and Delain 1975). Less attention has been paid to the experimental criteria necessary for spreading and visualisation by dark field electron microscopy of large intact issociations of DNA. This communication will report on those criteria in relation to the ultrastructure of the (approx. 1 x 10-14g) DNA component of the kinetoplast from Trypanosomes. An extraction method has been developed to eliminate native endonucleases and nuclear contamination and to isolate the kinetoplast DNA (KDNA) as a compact network of high molecular weight. In collaboration with Dr. Ch. Brack (Basel [nstitute of Immunology), we studied the conditions necessary to prepare this KDNA Tor dark field electron microscopy using the microdrop spreading technique.

Ultrastructural Cytopiasmic Changes of Adrenal Cortex During Pregnancy

1969 ◽  
Vol 27 ◽  
pp. 298-299
Author(s):  
T. M. Murad ◽  
Karen Israel ◽  
Jack C. Geer
Keyword(s):  
Adrenal Gland ◽  
Steroid Hormones ◽  
Adrenal Cortex ◽  
Lipid Droplets ◽  
Plasma Cholesterol ◽  
Adrenal Steroids ◽  
Dynamic Changes ◽  
Cortical Cells ◽  
Acetyl Coenzyme A ◽  
Adrenal Cortical Cells

Adrenal steroids are normally synthesized from acetyl coenzyme A via cholesterol. Cholesterol is also shown to enter the adrenal gland and to be localized in the lipid droplets of the adrenal cortical cells. Both pregnenolone and progesterone act as intermediates in the conversion of cholesterol into steroid hormones. During pregnancy an increased level of plasma cholesterol is known to be associated with an increase of the adrenal corticoid and progesterone. The present study is designed to demonstrate whether the adrenal cortical cells show any dynamic changes during pregnancy.

Properties of Isolated Mitochondria of Agaricus Bisporus: Their Relationship to Dormancy and the Germination of Spores

1973 ◽  
Vol 31 ◽  
pp. 458-459
Author(s):  
K. S. McCarty ◽  
R. F. Weave ◽  
L. Kemper ◽  
F. S. Vogel
Keyword(s):  
Mitochondrial Dna ◽  
Ethidium Bromide ◽  
Microscopic Examination ◽  
Agaricus Bisporus ◽  
Osmotic Shock ◽  
Electron Microscopic Examination ◽  
Electron Microscopic ◽  
Isolated Mitochondria ◽  
Dna Strands ◽  
Cytoplasmic Ribosomes

During the prodromal stages of sporulation in the Basidiomycete, Agaricus bisporus, mitochondria accumulate in the basidial cells, zygotes, in the gill tissues prior to entry of these mitochondria, together with two haploid nuclei and cytoplasmic ribosomes, into the exospores. The mitochondria contain prominent loci of DNA [Fig. 1]. A modified Kleinschmidt spread technique1 has been used to evaluate the DNA strands from purified whole mitochondria released by osmotic shock, mitochondrial DNA purified on CsCl gradients [density = 1.698 gms/cc], and DNA purified on ethidium bromide CsCl gradients. The DNA appeared as linear strands up to 25 u in length and circular forms 2.2-5.2 u in circumference. In specimens prepared by osmotic shock, many strands of DNA are apparently attached to membrane fragments [Fig. 2]. When mitochondria were ruptured in hypotonic sucrose and then fixed in glutaraldehyde, the ribosomes were released for electron microscopic examination.

Genetics of Hearing Loss: Contributions of Mitochondrial DNA

2002 ◽  
Vol 12 (1) ◽  
pp. 2-5
Author(s):  
Jill L. Elfenbein
Keyword(s):  
Hearing Loss ◽  
Mitochondrial Dna
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