scholarly journals Continuous positive airway pressure is associated with a decrease in pulmonary artery pressure in patients with obstructive sleep apnoea: A meta-analysis

Respirology ◽  
2014 ◽  
Vol 19 (5) ◽  
pp. 670-674 ◽  
Author(s):  
Xuefeng Sun ◽  
Jinmei Luo ◽  
Yi Xiao
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Meta Analysis ◽  
Sleep Apnoea ◽  
Artery Pressure ◽  
Obstructive Sleep

Atrial Natriuretic Peptide Release during Sleep in Patients with Obstructive Sleep Apnoea before and during Treatment with Nasal Continuous Positive Airway Pressure

1989 ◽  
Vol 77 (4) ◽  
pp. 407-411 ◽  
Author(s):  
J. Krieger ◽  
L. Laks ◽  
I. Wilcox ◽  
R. R. Grunstein ◽  
L. J. V. Costas ◽  
...  
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Pulmonary Artery ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Sleep Apnoea ◽  
Nasal Cpap ◽  
Obstructive Sleep

1. Plasma levels of atrial natriuretic peptide (ANP) were measured in seven patients with obstructive sleep apnoea (OSA) while they were awake, during repetitive apnoea and during treatment with nasal continuous positive airway pressure (CPAP). 2. ANP levels in both pulmonary artery and peripheral venous samples were elevated during apnoeic sleep and reduced when apnoea was prevented by nasal CPAP. Mean values of pulmonary artery ANP were 116.3 ± 17.9 pg/ml during apnoea and 64.8 ± 15.2 pg/ml (P < 0.05) on nasal CPAP. 3. It is concluded that there is increased ANP release during sleep in patients with OSA and that CPAP treatment normalizes ANP secretion. These findings may explain previously identified urinary abnormalities in OSA.

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