EFFECTS OF HIGH FLOW OXYGEN THERAPY ON OXYGEN DESATURATION INDEX IN PATIENTS WITH ACUTE ISCHEMIC STROKE

Respirology ◽  
2017 ◽  
Vol 22 ◽  
pp. 38-38
Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Fernando Gongora-Rivera ◽  
Walter Muruet ◽  
Beatriz Chavez ◽  
Hector Jorge Villarreal-Montemayor ◽  
Hector Jorge Villarreal-Velazquez

Objective: To determine the association between the Apnea-Hypopnea Index (AHI) and the Oxygen Desaturation Index (ODI) with the functional outcome in Acute Ischemic Stroke Patients and describe the prevalence of sleep respiratory disorders in this population. Methods: Patients with Acute Ischemic Stroke and NIHSS≤20, within 5 days of admission were tested with Apnea Link device. We analyzed demographic, clinical, and functional characteristics (mRS, NIHSS and Barthel) at outcome, 3 and 6 months after discharge. Results: We included 111 patients, 62% male, with 64.4 ± 12 years-old and Body Mass Index (BMI) of 27 (18-60). NIHSS was ≤12 in 82% of patients. 30% had an AHI ≥30. Patients were divided in 2 groups according to mRS score (0-3 and ≥4) at discharge, 3 and 6 months follow-up. No statistically significant difference was found between groups regarding demographic, clinical and risk factors with symptoms associated with sleep disorders. At 6 months, ODI were associated with a worse functional outcome (p=0.017), but not with AHI (p=0.157). Multivariate analysis revealed that NIHSS (p=0.01) and the ODI (p=0.021) were associated with a mRS ≥4 at 6 months follow-up after adjusting for age, gender and BMI. Conclusions: There is a high prevalence of sleep respiratory disorders in our population. The correlation found between ODI and the mRS at the 6 months follow-up suggests a prognostic potential in Ischemic Stroke.


2020 ◽  
Vol 5 (4) ◽  
pp. 1006-1010
Author(s):  
Jennifer Raminick ◽  
Hema Desai

Purpose Infants hospitalized for an acute respiratory illness often require the use of noninvasive respiratory support during the initial stage to improve their breathing. High flow oxygen therapy (HFOT) is becoming a more popular means of noninvasive respiratory support, often used to treat respiratory syncytial virus/bronchiolitis. These infants present with tachypnea and coughing, resulting in difficulties in coordinating sucking and swallowing. However, they are often allowed to feed orally despite having high respiratory rate, increased work of breathing and on HFOT, placing them at risk for aspiration. Feeding therapists who work with these infants have raised concerns that HFOT creates an additional risk factor for swallowing dysfunction, especially with infants who have compromised airways or other comorbidities. There is emerging literature concluding changes in pharyngeal pressures with HFOT, as well as aspiration in preterm neonates who are on nasal continuous positive airway pressure. However, there is no existing research exploring the effect of HFOT on swallowing in infants with acute respiratory illness. This discussion will present findings from literature on HFOT, oral feeding in the acutely ill infant population, and present clinical practice guidelines for safe feeding during critical care admission for acute respiratory illness. Conclusion Guidelines for safety of oral feeds for infants with acute respiratory illness on HFOT do not exist. However, providers and parents continue to want to provide oral feeds despite clinical signs of respiratory distress and coughing. To address this challenge, we initiated a process change to use clinical bedside evaluation and a “cross-systems approach” to provide recommendations for safer oral feeds while on HFOT as the infant is recovering from illness. Use of standardized feeding evaluation and protocol have improved consistency of practice within our department. However, further research is still necessary to develop clinical practice guidelines for safe oral feeding for infants on HFOT.


Author(s):  
C. Harduin ◽  
B. Allaouchiche ◽  
J. Nègre ◽  
I. Goy‐Thollot ◽  
A. Barthélemy ◽  
...  

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