scholarly journals TREATMENT OF NON-SMALL CELL LUNG CANCER WITH ATEZOLIZUMAB: A CASE SERIES STUDY

Respirology ◽  
2018 ◽  
Vol 23 ◽  
pp. 296-297
2013 ◽  
Vol 100 (12) ◽  
pp. E30-E37 ◽  
Author(s):  
Sylvestre Le Moulec ◽  
Julien Hadoux ◽  
Éric Gontier ◽  
Cyrus Chargari ◽  
Carole Helissey ◽  
...  

2019 ◽  
Vol Volume 12 ◽  
pp. 7785-7790 ◽  
Author(s):  
Huiying Li ◽  
Tingting Yu ◽  
Mingmin Huang ◽  
Aibin Guo ◽  
Xiaoping Qian ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Nagla Abdel Karim ◽  
Ananta Bhatt ◽  
Lauren Chiec ◽  
Richard Curry

Lung cancer is the most common cause of cancer related mortality in men and women. Approximately 15% of lung cancers are small cell type. Chemotherapy and radiation are the mainstay treatments. Currently, the standard chemotherapy regimen includes platinum/etoposide. For extensive small cell lung cancer, irinotecan and cisplatin have also been used. Patients with relapsed small cell lung cancer have a very poor prognosis, and the morbidity increases with brain metastases. Approximately 10%–14% of small cell lung cancer patients exhibit brain metastases at the time of diagnosis, which increases to 50%–80% as the disease progresses. Mean survival with brain metastases is reported to be less than six months, thus calling for improved regimens. Here we present a case series of patients treated with irinotecan for progressive brain metastases in small cell lung cancer, which serves as a reminder of the role of systemic chemotherapy in this setting.


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