Chicken ISG12(2) attenuates Newcastle disease virus and enhances the efficiency of Newcastle disease vaccine via activating immune pathways

2021 ◽  
Author(s):  
Haijin Liu ◽  
Jianxia Tian ◽  
Kejia Lu ◽  
Zhao Guan ◽  
Yangyang Li ◽  
...  
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Immune Pathways ◽  
Newcastle Disease Vaccine

scholarly journals Efficacy of a genotype 2 Newcastle disease vaccine (Avinew®) against challenge with highly virulent genotypes 5d and 3d

2009 ◽  
Vol 80 (3) ◽  
Author(s):  
D.G. Bwala ◽  
C. Abolnik ◽  
A. Van Wyk ◽  
E. Cornelius ◽  
S.P.R. Bisschop
Keyword(s):  
South Africa ◽  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Disease Outbreaks ◽  
Challenge Virus ◽  
Genotype 2 ◽  
Significant Difference ◽  
Specific Pathogen ◽  
Newcastle Disease Vaccine

Since 2002, following its introduction, the lineage 5d Newcastle disease virus (so-called Goose paramyxovirus -GPMV) strain has caused numerous disease outbreaks among commercial and backyard poultry in South Africa, raising questions about the ability of commercially available Newcastle disease vaccines to fully protect poultry against the strain. This study aimed to determine whether there are differences in the level of protection offered by Avinew® Newcastle disease vaccine against GPMV virus as compared with a 3d Newcastle disease virus isolated in South Africa in 1993 (Rainbow challenge virus - RCV) strain. Six groups of 10-day-old, specific pathogen-free chickens were vaccinated with doses of 103.0, 104.5 and 106.0 EID50 of Avinew® vaccine and challenged at 4 weeks of age intramuscularly at a dose of 105.3EID50/ 0.2 mℓ/bird of GPMV and RCV. No statistically significant difference could be found in the protection offered by Avinew® vaccine against GPMV as compared to RCV challenge. The protection offered against the ND challenge was found to be dose dependent. At the recommended field dose of 106.0 EID50 the vaccine gave 100 % protection from mortality against both the challenge viruses, but not against infection and replication of the viruses, as gross lesions were evident even in apparently healthy birds that survived the challenge. The protective dose (PD90) of the Avinew® vaccine against GPMV challenge was calculated at 104.38 and against that of RCV at 104.43.

Immunity Elicited by a Turkey Herpesvirus-Vectored Newcastle Disease Vaccine in Turkey Against Challenge With a Recent Genotype IV Newcastle Disease Virus Field Strain

2017 ◽  
Vol 61 (3) ◽  
pp. 378-386 ◽  
Author(s):  
Abderrazak El Khantour ◽  
Sami Darkaoui ◽  
Tímea Tatár-Kis ◽  
Tamás Mató ◽  
Amal Essalah-Bennani ◽  
...  
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Field Strain ◽  
Newcastle Disease Vaccine

scholarly journals Growth performance and immune response to Newcastle disease in four gene pools of indigenous chicken in Rwanda

2020 ◽  
Vol 1 (2) ◽  
pp. 42-50
Author(s):  
Richard Habimana ◽  
Kiplangat Ngeno ◽  
Anselme Shyaka ◽  
Martin Ntawubizi ◽  
Janvier Mahoro ◽  
...  
Keyword(s):  
Immune Response ◽  
Newcastle Disease Virus ◽  
Growth Performance ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Gene Pool ◽  
Growth Patterns ◽  
Gene Pools ◽  
Indigenous Chicken ◽  
Newcastle Disease Vaccine

In Rwanda, the most prevalent livestock farming activity carried out to improve livelihoods in rural areas is poultry farming. The most common bird species raised for egg and meat production is indigenous chicken (IC). Despite its economic significance, the improvement programs in Rwanda have given IC little attention. There is, therefore, little documentation on their production and disease resistance performance. This study aimed at evaluating the growth performance and immunologic response of IC against Newcastle disease vaccine in four gene pools in Rwanda. One hundred eighty-nine (189) IC from four gene pools were kept on-station using a completely randomized design. Thereafter, the IC were vaccinated with a live commercial Newcastle disease virus. Data on body weight were collected weekly for 20 weeks whereas serum samples were collected after 35 days. Antibody responses were determined using indirect ELISA. Analysis of variance was performed using the SAS Generalised Linear Model procedure. Growth patterns were modelled using the logistic function. Results revealed a highly significant difference (P<0.001) for growth performance and antibody response to Newcastle disease vaccine among the four gene pools. Gene pool A was the heaviest (1.6 kg) in the period of 20 weeks and gene pool C expressed the highest immune response (8,161antibody titres) for Newcastle disease vaccine (P<0.001). The results indicated that the selection of gene pool A in breeding could yield IC with good growth performance trait whilst gene pool C could be selected for its higher immunity against Newcastle disease virus.

IMMUNOLOGICAL STUDY ON CHICKENS VACCINATED WITH A COMBINED INACTIVATED SALMONELLA ENTERITIDIS AND NEWCASTLE DISEASE VIRUS (ND) VACCINE

2011 ◽  
Vol 9 (2) ◽  
pp. 59-72
Author(s):  
Anhar, M. Abd-ElMoaty ◽  
Hanan, A. Ahmed ◽  
Nahed, I. Mohamed ◽  
Mervat, A. El-Koffy
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Salmonella Enteritidis ◽  
Immunological Study

Characterization of Recent Isolates of Newcastle Disease virus

2016 ◽  
Vol 21 (1) ◽  
pp. 235-248
Author(s):  
Amani Saleh ◽  
Rola Ali ◽  
Mohamed Fawzy ◽  
Mokhtar Eltarabily
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease

Comparative Studies between Thermostable Strains of Newcastle Disease Virus in Preparation of Live Vaccine

2015 ◽  
Vol 43 (2) ◽  
pp. 33-39
Author(s):  
Ola Hassan ◽  
O Salman ◽  
Hoda Tawfik
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Comparative Studies ◽  
Live Vaccine

Relation of interferon synthesis to abortive replication of Newcastle disease virus in L cells.

1968 ◽  
Vol 2 (1) ◽  
pp. 81-82 ◽  
Author(s):  
J S Youngner ◽  
A W Scott
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
L Cells
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