Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients (CANDLE‐KIT): a Multicenter, 2×2 Factorial, Open‐label, Randomized Clinical Trial

2021 ◽  
Author(s):  
Yoshitsugu Obi ◽  
Naotsugu Ichimaru ◽  
Yusuke Sakaguchi ◽  
Kazuhiro Iwadoh ◽  
Daisuke Ishii ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Vitamin D ◽  
Randomized Clinical Trial ◽  
Kidney Transplant ◽  
Vitamin D Supplementation ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Open Label

A randomized clinical trial comparing Nitrofurazone‐coated and uncoated urinary catheters in kidney transplant recipients: Results from a pilot study

2018 ◽  
Vol 21 (2) ◽  
pp. e13031 ◽  
Author(s):  
Fernando Gatti Menezes ◽  
Luci Corrêa ◽  
Jose Osmar Medina‐Pestana ◽  
Wilson Ferreira Aguiar ◽  
Luis Fernando Aranha Camargo
Keyword(s):  
Clinical Trial ◽  
Pilot Study ◽  
Randomized Clinical Trial ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Urinary Catheters

scholarly journals Effects of vitamin D supplementation on red cell indices and cytokines in patients with thalassemia: An open-label randomized clinical trial

2019 ◽  
pp. 170-179
Keyword(s):  
Clinical Trial ◽  
Vitamin D ◽  
Randomized Clinical Trial ◽  
Thalassemia Major ◽  
Vitamin D Supplementation ◽  
Beta Thalassemia ◽  
Red Cell ◽  
Open Label ◽  
Hematological Indices ◽  
Red Cell Indices

Background and aim Deficiency of vitamin D is known as a health problem all over the world and a recognized clinical complication of beta thalassemia patients. Vitamin D acts as a hormone at the nuclear receptor rendering it a beneficial medication for a number of diseases. It is believed that vitamin D is important in the modulation of the inflammation system by regulating the formation of inflammatory cytokines and immune cells. This study aimed to investigate the effect of vitamin D supplementation on the red cell indices and cytokines levels in patients with beta thalassemia major, in an open label randomized clinical trial. Patients and Methods: this study performed an open-label randomized clinical trial in patients with beta thalassemia major. Forty-six patients completed the eight weeks clinical trial and were allocated to administer oral vitamin D3 supplement of 100,000 IU every two weeks as an add-on treatment. During the study, hematological indices, serum iron, ferritin, vitamin D, calcium and inflammatory markers (interleukin-6, interleukin-2 and interleukin-10) were evaluated before (at baseline) and after vitamin D supplementation for 8 weeks. Results: Vitamin D3 supplements significantly decreases interleukin-6 levels and elevates the serum levels of anti-inflammatory cytokines IL-2 and IL-10, it also significantly reduced serum ferritin level, but it did not alter the hematological indices. Conclusion: Our results suggest that administration of vitamin D has a potential anti-inflammatory role in beta thalassemia patients and reduces serum ferritin levels, which may reduce the burdens of iron overload in thalassemia patients.

Effects of Dietary Sodium Restriction in Kidney Transplant Recipients Treated With Renin-Angiotensin-Aldosterone System Blockade: A Randomized Clinical Trial

2016 ◽  
Vol 67 (6) ◽  
pp. 936-944 ◽  
Author(s):  
Laura V. de Vries ◽  
Linn C. Dobrowolski ◽  
Jacqueline J.O.N. van den Bosch ◽  
Ineke J. Riphagen ◽  
C.T. Paul Krediet ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Kidney Transplant ◽  
Dietary Sodium ◽  
Sodium Restriction ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Renin Angiotensin Aldosterone System ◽  
Renin Angiotensin ◽  
Dietary Sodium Restriction

scholarly journals Comparing the effect of immediate versus delayed initiation of tacrolimus on delayed graft function in Kidney transplant recipients: A randomized open-label clinical trial

2018 ◽  
Vol 7 (2) ◽  
pp. 69 ◽  
Author(s):  
Simin Dashti-Khavidaki ◽  
Maryam Ghadimi ◽  
Mohammad-Reza Khatami ◽  
Mitra Mahdavi-Mazdeh ◽  
Mansoor Gatmiri ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Kidney Transplant ◽  
Graft Function ◽  
Delayed Graft Function ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Open Label ◽  
Delayed Initiation

scholarly journals Effect of an intensive nutrition intervention of a high protein and low glycemic-index diet on weight of kidney transplant recipients: study protocol for a randomized clinical trial

Trials ◽  
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Elis Forcellini Pedrollo ◽  
Bruna Bellincanta Nicoletto ◽  
Larissa Salomoni Carpes ◽  
Júlia de Melo Cardoso de Freitas ◽  
Julia Roberta Buboltz ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Kidney Transplant ◽  
Study Protocol ◽  
Glycemic Index ◽  
High Protein ◽  
Nutrition Intervention ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Low Glycemic Index

scholarly journals The impact of everolimus in reducing cytomegalovirus events in kidney transplant recipients on steroid-avoidance strategy: 3-year follow-up of a randomized clinical trial

2018 ◽  
Vol 31 (12) ◽  
pp. 1345-1356 ◽  
Author(s):  
Tainá Veras de Sandes-Freitas ◽  
Petrucia Maria Antero Pinheiro ◽  
Maria Luíza de Mattos Brito Oliveir Sales ◽  
Celi Melo Girão ◽  
Érika Fernandes Campos ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Avoidance Strategy ◽  
The Impact ◽  
Steroid Avoidance
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