Intrinsic and synaptic mechanisms controlling the expiratory activity of excitatory lateral parafacial neurones of rats

2021 ◽  
Author(s):  
Karolyne S. Magalhães ◽  
Melina P. da Silva ◽  
André S. Mecawi ◽  
Julian F. R. Paton ◽  
Benedito H. Machado ◽  
...  
Keyword(s):  
Synaptic Mechanisms

scholarly journals Rapid multi-directed cholinergic transmission in the central nervous system

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Santhosh Sethuramanujam ◽  
Akihiro Matsumoto ◽  
Geoff deRosenroll ◽  
Benjamin Murphy-Baum ◽  
J Michael McIntosh ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ganglion Cells ◽  
Release Site ◽  
Amacrine Cells ◽  
Global Scale ◽  
Cholinergic Transmission ◽  
Data Set ◽  
The Central Nervous System ◽  
Synaptic Mechanisms

AbstractIn many parts of the central nervous system, including the retina, it is unclear whether cholinergic transmission is mediated by rapid, point-to-point synaptic mechanisms, or slower, broad-scale ‘non-synaptic’ mechanisms. Here, we characterized the ultrastructural features of cholinergic connections between direction-selective starburst amacrine cells and downstream ganglion cells in an existing serial electron microscopy data set, as well as their functional properties using electrophysiology and two-photon acetylcholine (ACh) imaging. Correlative results demonstrate that a ‘tripartite’ structure facilitates a ‘multi-directed’ form of transmission, in which ACh released from a single vesicle rapidly (~1 ms) co-activates receptors expressed in multiple neurons located within ~1 µm of the release site. Cholinergic signals are direction-selective at a local, but not global scale, and facilitate the transfer of information from starburst to ganglion cell dendrites. These results suggest a distinct operational framework for cholinergic signaling that bears the hallmarks of synaptic and non-synaptic forms of transmission.

Synaptic mechanisms of the action of subcortical formations on motoneurons in cat facial nerve

1986 ◽  
Vol 17 (6) ◽  
pp. 580-587
Author(s):  
L. R. Manvelyan ◽  
V. V. Fanardzhyan
Keyword(s):  
Facial Nerve ◽  
Synaptic Mechanisms

Dynamics of cholinergic synaptic mechanisms in rat hippocampus after stress

1985 ◽  
Vol 343 (2) ◽  
pp. 314-319 ◽  
Author(s):  
Yoram Finkelstein ◽  
Benjamin Koffler ◽  
Jose M. Rabey ◽  
Gad M. Gilad
Keyword(s):  
Rat Hippocampus ◽  
Synaptic Mechanisms

scholarly journals Synaptic Mechanisms of Blast-Induced Brain Injury

2016 ◽  
Vol 7 ◽  
Author(s):  
Andrzej Przekwas ◽  
Mahadevabharath R. Somayaji ◽  
Raj K. Gupta
Keyword(s):  
Brain Injury ◽  
Synaptic Mechanisms

scholarly journals Kindling, Unit Discharge Patterns and Neural Plasticity

1975 ◽  
Vol 2 (4) ◽  
pp. 395-405 ◽  
Author(s):  
Ronald Racine ◽  
Larry Tuff ◽  
Josef Zaide
Keyword(s):  
Neural Plasticity ◽  
Evoked Potential ◽  
Spine Density ◽  
Unit Discharge ◽  
Cell Discharge ◽  
Kindling Effect ◽  
Discharge Patterns ◽  
Apical Dendrites ◽  
Effect Experiment ◽  
Synaptic Mechanisms

SUMMARY:Two approaches to the study of the kindling phenomenon were discussed: 1) an attempt to identify the pattern of neural activity required to produce the changes underlying kindling and 2) an investigation into the nature of those changes. Three experiments were reported that used the neocortical transcallosal system as a monosynaptic model system in which to study possible synaptic mechanisms of the kindling effect. Experiment I showed an increase in the transcallosal evoked potential following neocortical kindling. Experiment II showed an increase in the strength of the transcallosal evoked cell discharge following neocortical kindling. Experiment III reported the results of an histological examination of neocortical tissue in kindled and non-kindled animals using the Golgi-Cox technique. Spine density, spine dimension and branching were measured for pyramidal cell apical dendrites. No differences were found between primary and secondary (contralateral) foci or between kindled and non-kindled animals.

Catecholamine systems of retina: A model for studying synaptic mechanisms

Life Sciences ◽  
1984 ◽  
Vol 35 (11) ◽  
pp. 1135-1147 ◽  
Author(s):  
M. Hadjiconstantinou ◽  
N.H. Neff
Keyword(s):  
Synaptic Mechanisms

Synaptic mechanisms involved in responses of chromaticity horizontal cells of turtle retina

Nature ◽  
1980 ◽  
Vol 284 (5751) ◽  
pp. 58-60 ◽  
Author(s):  
Marco Piccolino ◽  
Jacques Neyton ◽  
Hersch M. Gerschenfeld
Keyword(s):  
Horizontal Cells ◽  
Synaptic Mechanisms

Activation of postganglionic neurones via non-nicotinic synaptic mechanisms by stimulation of thin preganglionic axons

1984 ◽  
Vol 401 (3) ◽  
pp. 318-320 ◽  
Author(s):  
W. Jänig ◽  
R. Krauspe ◽  
G. Wiedersatz
Keyword(s):  
Synaptic Mechanisms ◽  
Stimulation Of ◽  
Postganglionic Neurones
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