Synergistic interaction between sensory inputs and propriospinal signalling underlying quadrupedal locomotion

2021 ◽  
Vol 599 (19) ◽  
pp. 4477-4496
Author(s):  
Marie Boulain ◽  
Inès Khsime ◽  
Mélissa Sourioux ◽  
Muriel Thoby‐Brisson ◽  
Grégory Barrière ◽  
...  
Keyword(s):  
Synergistic Interaction ◽  
Quadrupedal Locomotion ◽  
Sensory Inputs

scholarly journals Cervicolumbar Coordination in Mammalian Quadrupedal Locomotion: Role of Spinal Thoracic Circuitry and Limb Sensory Inputs

2012 ◽  
Vol 32 (3) ◽  
pp. 953-965 ◽  
Author(s):  
L. Juvin ◽  
J.-P. Le Gal ◽  
J. Simmers ◽  
D. Morin
Keyword(s):  
Quadrupedal Locomotion ◽  
Sensory Inputs

Children With Developmental Coordination Disorder Respond Poorly to Altered Sensory Inputs While Standing

2004 ◽  
Author(s):  
Rong-Ju Cherng ◽  
Yung-Wen Hsu ◽  
Yung-Jung Chen
Keyword(s):  
Developmental Coordination Disorder ◽  
Sensory Inputs ◽  
Coordination Disorder

Loneliness, social isolation, their synergistic interaction, and mortality.

2018 ◽  
Vol 37 (9) ◽  
pp. 808-813 ◽  
Author(s):  
Johannes Beller ◽  
Adina Wagner
Keyword(s):  
Social Isolation ◽  
Synergistic Interaction

Synergistic interaction of triterpenoid saponins and plant protein toxins

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
A Weng ◽  
M Thakur ◽  
F Beceren-Braun ◽  
R Gilabert-Oriol ◽  
S Boettger ◽  
...  
Keyword(s):  
Synergistic Interaction ◽  
Plant Protein ◽  
Triterpenoid Saponins ◽  
Protein Toxins

Triggers of Thought: Impressions within Hume’s Theory of Mind

2010 ◽  
Vol 13 (1) ◽  
pp. 105-121
Author(s):  
Anik Waldow
Keyword(s):  
Theory Of Mind ◽  
Associative Processes ◽  
Sensory Inputs ◽  
The World ◽  
Theories Of Meaning ◽  
Conceptual Resources

This essay argues that Humean impressions are triggers of associative processes, which enable us to form stable patterns of thought that co-vary with our experiences of the world. It will thus challenge the importance of the Copy Principle by claiming that it is the regularity with which certain kinds of sensory inputs motivate certain sets of complex ideas that matters for the discrimination of ideas. This reading is conducive to Hume’s account of perception, because it avoids the impoverishment of conceptual resources so typical for empiricist theories of meaning and explains why ideas should be based on impressions, although impressions cannot be known to mirror matters of fact. Dieser Aufsatz argumentiert dafür, dass humesche Eindrücke („impressions“) Auslöser von assoziativen Prozessen sind, welche es uns ermöglichen, stabile Denkmuster zu bilden, die mit unseren Erfahrungen der Welt kovariant sind. Der Aufsatz stellt somit die Wichtigkeit des Kopien-Prinzips in Frage, nämlich dadurch, dass behauptet wird, für die Unterscheidung der Ideen sei die Regelmäßigkeit maßgeblich, mit der gewisse Arten von sensorischen Eingaben gewisse Mengen von komplexen Ideen motivieren. Diese Lesart trägt zu einem Verständnis von Humes Auffassung der Wahrnehmung bei, da sie die Verarmung der begrifflichen Mittel, die für empiristische Theorien der Bedeutung so typisch ist, vermeidet und erklärt, warum Ideen auf Eindrücken basieren sollten, obwohl Eindrücke nicht als Abbildungen von Tatsachen erkannt werden können.

In Vitro Synergistic Interaction Between Amide Piplartine and Antimicrobial Peptide Dermaseptin Against Schistosoma mansoni Schistosomula and Adult Worms

2012 ◽  
Vol 20 (2) ◽  
pp. 301-309 ◽  
Author(s):  
J. de Moraes ◽  
J. Keiser ◽  
K. Ingram ◽  
C. Nascimento ◽  
L.F. Yamaguchi ◽  
...  
Keyword(s):  
Antimicrobial Peptide ◽  
Schistosoma Mansoni ◽  
Synergistic Interaction

scholarly journals Synergistic Interaction of MEK Kinase 2, c-Jun N-Terminal Kinase (JNK) Kinase 2, and JNK1 Results in Efficient and Specific JNK1 Activation

2000 ◽  
Vol 20 (7) ◽  
pp. 2334-2342 ◽  
Author(s):  
Jinke Cheng ◽  
Jianhua Yang ◽  
Ying Xia ◽  
Michael Karin ◽  
Bing Su
Keyword(s):  
Complex Formation ◽  
Molecular Basis ◽  
Synergistic Interaction ◽  
Specific Flow ◽  
Mitogen Activated Protein Kinases ◽  
Mapk Kinase ◽  
Signaling Complex ◽  
Mapk Cascades ◽  
Mitogen Activated Protein ◽  
Flow Of Information

ABSTRACT Mitogen-activated protein kinases (MAPKs) are activated through cascades or modules consisting of a MAPK, a MAPK kinase (MAPKK), and a MAPKK kinase (MAPKKK). Investigating the molecular basis of activation of the c-Jun N-terminal kinase (JNK) subgroup of MAPK by the MAPKKK MEKK2, we found that strong and specific JNK1 activation by MEKK2 was mediated by the MAPKK JNK kinase 2 (JNKK2) rather than by JNKK1 through formation of a tripartite complex consisting of MEKK2, JNKK2, and JNK1. No scaffold protein was required for the MEKK2-JNKK2-JNK1 tripartite-complex formation. Expression of JNK1, JNKK2, and MEKK2 significantly augmented the coprecipitation of, respectively, MEKK2-JNKK2, MEKK2-JNK1, and JNKK2-JNK1, indicating that the interaction of MEKK2, JNKK2, and JNK1 is synergistic. Finally, the JNK1 was activated more efficiently in the MEKK2-JNKK2-JNK1 complex than was the JNK1 excluded from the complex. Thus, formation of a signaling complex through synergistic interaction of a MAPKKK, a MAPKK, and a MAPK molecule like MEKK2-JNKK2-JNK1 is likely to be responsible for the efficient, specific flow of information via MAPK cascades.

scholarly journals Corticostriatal control of defense behavior in mice induced by auditory looming cues

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Zhong Li ◽  
Jin-Xing Wei ◽  
Guang-Wei Zhang ◽  
Junxiang J. Huang ◽  
Brian Zingg ◽  
...  
Keyword(s):  
Essential Role ◽  
Neural Circuits ◽  
Temporal Dynamics ◽  
Defense Behavior ◽  
Innate Defense ◽  
Sensory Inputs ◽  
Corticostriatal Projections ◽  
Behavioral Transition ◽  
Auditory Looming

AbstractAnimals exhibit innate defense behaviors in response to approaching threats cued by the dynamics of sensory inputs of various modalities. The underlying neural circuits have been mostly studied in the visual system, but remain unclear for other modalities. Here, by utilizing sounds with increasing (vs. decreasing) loudness to mimic looming (vs. receding) objects, we find that looming sounds elicit stereotypical sequential defensive reactions: freezing followed by flight. Both behaviors require the activity of auditory cortex, in particular the sustained type of responses, but are differentially mediated by corticostriatal projections primarily innervating D2 neurons in the tail of the striatum and corticocollicular projections to the superior colliculus, respectively. The behavioral transition from freezing to flight can be attributed to the differential temporal dynamics of the striatal and collicular neurons in their responses to looming sound stimuli. Our results reveal an essential role of the striatum in the innate defense control.

scholarly journals The Independent Evolution of Dorsal Pallia in Multiple Vertebrate Lineages

2021 ◽  
pp. 1-12
Author(s):  
Georg F. Striedter ◽  
R. Glenn Northcutt
Keyword(s):  
Olfactory Bulbs ◽  
Sensory Inputs ◽  
Independent Evolution ◽  
Sensory Modalities ◽  
Olfactory Input ◽  
Cartilaginous Fishes

Comparative neurobiologists have long wondered when and how the dorsal pallium (e.g., mammalian neocortex) evolved. For the last 50 years, the most widely accepted answer has been that this structure was already present in the earliest vertebrates and, therefore, homologous between the major vertebrate lineages. One challenge for this hypothesis is that the olfactory bulbs project throughout most of the pallium in the most basal vertebrate lineages (notably lampreys, hagfishes, and lungfishes) but do not project to the putative dorsal pallia in teleosts, cartilaginous fishes, and amniotes (i.e., reptiles, birds, and mammals). To make sense of these data, one may hypothesize that a dorsal pallium existed in the earliest vertebrates and received extensive olfactory input, which was subsequently lost in several lineages. However, the dorsal pallium is notoriously difficult to delineate in many vertebrates, and its homology between the various lineages is often based on little more than its topology. Therefore, we suspect that dorsal pallia evolved independently in teleosts, cartilaginous fishes, and amniotes. We further hypothesize that the emergence of these dorsal pallia was accompanied by the phylogenetic restriction of olfactory projections to the pallium and the expansion of inputs from other sensory modalities. We do not deny that the earliest vertebrates may have possessed nonolfactory sensory inputs to some parts of the pallium, but such projections alone do not define a dorsal pallium.

Influence of Sargassum pallidum and the synergistic interaction mechanism of 6-gingerol and poricoic acid A on inhibiting ovalbumin glycation

2021 ◽  
Vol 12 (19) ◽  
pp. 9315-9326
Author(s):  
Xie Xing ◽  
Chen Chun ◽  
Fu Xiong ◽  
Liu Rui-Hai
Keyword(s):  
Interaction Mechanism ◽  
Synergistic Interaction ◽  
Active Compounds ◽  
Sargassum Pallidum

This study aimed to investigate the antiglycation capacity of Sargassum pallidum extract on ovalbumin (OVA) glycation, and the interaction mechanism of its active compounds, including 6-gingerol (6G) and poricoic acid A (PA).

Sign in / Sign up

Export Citation Format

Share Document