scholarly journals The effect of intrafetal infusion of metyrapone on arterial blood pressure and on the arterial blood pressure response to angiotensin II in the sheep fetus during late gestation

2003 ◽  
Vol 552 (2) ◽  
pp. 621-633 ◽  
Author(s):  
K. E. Warnes
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Arterial Blood Pressure ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Late Gestation ◽  
Arterial Blood ◽  
Sheep Fetus

Angiotensin I conversion and vascular reactivity in pathophysiological states in dogs

1980 ◽  
Vol 48 (2) ◽  
pp. 308-312 ◽  
Author(s):  
P. J. Leuenberger ◽  
S. A. Stalcup ◽  
L. M. Greenbaum ◽  
R. B. Mellins ◽  
G. M. Turino
Keyword(s):  
Blood Pressure ◽  
Enzyme Activity ◽  
Angiotensin Ii ◽  
Vascular Reactivity ◽  
Blood Pressure Response ◽  
Acute Hypoxia ◽  
Pressure Response ◽  
Converting Enzyme ◽  
Angiotensin I ◽  
Arterial Blood

To determine if angiotension converting enzyme activity is altered by acute pathophysiological insults, we assessed angiotensin I conversion using a blood pressure response technique in anesthetized dogs studied during acute 100% O2 breathing and acute acid-base derangements. Also, we determined systemic vascular reactivity to angiotensin II by measuring the magnitude and duration of the arterial blood pressure response to intra-arterial injections of angiotensin II under these same conditions. Angiotensin I conversion found in normoxia [91 +/- 7 (SD)%] was unchanged by acute acidosis, alkalosis, and hyperoxia. During acute hyperoxia the mean half time of the hypertensive response increased from 68 +/- 25 (SD) s at a PaO2 of 112 +/- 18 (SD) Torr to 100 +/- 34 (SD) s at a PaO2 of 491 +/- 47 (SD) Torr (P less than 0.01). No other pathophysiological condition studied had any effect on reactivity of systemic vasculature to angiotensin II. We conclude that, except during acute hypoxia as previously shown, converting enzyme activity is resistant to other pathophysiological insults and that vascular responsiveness to angiotensin II is enhanced by hyperoxia.

scholarly journals Intra-arterial blood pressure response in hypertensive subjects during low- and high-intensity resistance exercise

Clinics ◽  
2010 ◽  
Vol 65 (3) ◽  
pp. 271-277 ◽  
Author(s):  
Sandra de Souza Nery ◽  
Ricardo Saraceni Gomides ◽  
Giovanio Vieira da Silva ◽  
Claudia Lucia de Moraes Forjaz ◽  
Décio Mion Jr ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Resistance Exercise ◽  
Arterial Blood Pressure ◽  
High Intensity ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Arterial Blood

Arterial blood pressure response to rowing

1994 ◽  
Vol 26 (6) ◽  
pp. 715-719 ◽  
Author(s):  
PHILIP S. CLIFFORD ◽  
BIRGITTE HANEL ◽  
NIELS H. SECHER
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Arterial Blood

Physical Activity and Arterial Blood Pressure Response to Handgrip Exercise

2019 ◽  
Vol 45 (1) ◽  
pp. 62-68
Author(s):  
V. V. Gultyaeva ◽  
M. I. Zinchenko ◽  
D. Yu. Uryumtsev ◽  
V. G. Grishin ◽  
O. V. Grishin
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Handgrip Exercise ◽  
Arterial Blood

Cardiovascular consequences of microinjection of vasopressin and angiotensin II in the area postrema

1993 ◽  
Vol 265 (3) ◽  
pp. R625-R631 ◽  
Author(s):  
V. L. Lowes ◽  
L. E. McLean ◽  
N. W. Kasting ◽  
A. V. Ferguson
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Angiotensin Ii ◽  
Area Postrema ◽  
Blood Pressure Response ◽  
Pressor Response ◽  
Systemic Administration ◽  
Pressure Response ◽  
Arterial Blood ◽  
At1 Antagonist

Microinjection of angiotensin II (ANG II) into the area postrema (AP) of urethan-anesthetized male Sprague-Dawley rats elicited statistically significant increases in mean arterial blood pressure at doses ranging from 10 pg to 500 ng (10 pg, mean +/- SE, 10.8 +/- 1.1 mmHg, P < 0.001; 250 ng, 15.2 +/- 2.6 mmHg, P < 0.001). Heart rate was also significantly increased at doses > 10 pg, although these increases were not dose dependent. Systemic administration of losartan (Dup-753), an AT1 antagonist, was able to significantly reduce the pressor response to 250 ng ANG (post-losartan: 81.9 +/- 9.5% reduction in blood pressure response, P < 0.0001), whereas PD123319, an AT2 antagonist, was without significant effect (P > 0.1). Microinjection of vasopressin (VP) (10 pg-500 ng) into the AP also resulted in statistically significant increases in blood pressure at doses ranging from 10 to 100 pg (10 pg, 7.0 +/- 1.5 mmHg, P < 0.05) and 100-500 ng (250 ng, 12.2 +/- 1.8 mmHg, P < 0.0001). Small but significant changes in heart rate were observed only at 100 pg and 100 ng. Systemic administration of a V1 antagonist significantly attenuated the increases in blood pressure in response to 50, 100, and 250 ng VP (250 ng, post-V1 antagonist: 66.4 +/- 8.6% reduction in blood pressure response, P < 0.001), whereas [desamino,D-Arg8]vasopressin (DDAVP), a V2 agonist, had a depressor effect when microinjected directly into the AP (250 ng, -9.9 +/- 1.6 mmHg, P < 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)

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