scholarly journals Huntingtin-associated protein 1 regulates exocytosis, vesicle docking, readily releasable pool size and fusion pore stability in mouse chromaffin cells

2014 ◽  
Vol 592 (7) ◽  
pp. 1505-1518 ◽  
Author(s):  
Kimberly D. Mackenzie ◽  
Michael D. Duffield ◽  
Heshan Peiris ◽  
Lucy Phillips ◽  
Mark P. Zanin ◽  
...  
1979 ◽  
Vol 83 (1) ◽  
pp. 53-59 ◽  
Author(s):  
A. J.-M. C. PICKERING ◽  
G. FINK

SUMMARY The size of the 'readily releasable pool' of luteinizing hormone at various times of the oestrous cycle has been determined by injecting a supramaximal dose of luteinizing hormone releasing factor (LH-RF) i.v. into rats anaesthetized with sodium pentobarbitone. In an attempt to block replenishment of the 'pool' during release, cycloheximide was administered 30 min before LH-RF. A 20-fold increase in pool size occurred between the morning of dioestrus and the evening of pro-oestrus in the absence of any significant change in total pituitary content of LH. This suggests that increased responsiveness may be brought about by a change in the receptor-release apparatus and/or a transfer of LH from a 'storage pool' which leads to an apparent increase in the proportion of LH available for release.


2006 ◽  
Vol 103 (48) ◽  
pp. 18332-18337 ◽  
Author(s):  
R. F. G. Toonen ◽  
K. Wierda ◽  
M. S. Sons ◽  
H. de Wit ◽  
L. N. Cornelisse ◽  
...  

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