Deep Learning Algorithm for Image Classification of Waveforms Obtained From Electrically Stimulated Hypoxic Skeletal Muscle Bundles

Author(s):  
Weston Upchurch ◽  
Alex Deakyne ◽  
David A. Ramirez ◽  
Paul A. Iaizzo

Abstract Acute compartment syndrome is a serious condition that requires urgent surgical treatment. While the current emergency treatment is straightforward — relieve intra-compartmental pressure via fasciotomy — the diagnosis is often a difficult one. A deep neural network is presented here that has been trained to detect whether isolated muscle bundles were exposed to hypoxic conditions and became ischemic.

2020 ◽  
Vol 17 (8) ◽  
pp. 3328-3332
Author(s):  
S. Gowri ◽  
U. Srija ◽  
P. A. Shirley Divya ◽  
J. Jabez ◽  
J. S. Vimali

Classifying and predicting the Mangrove species is one of the most important applications in our ecosystem. Mangroves are the most endangered species that contributes in playing a greater role in our ecosystem. It mainly prevents the calamities like soil erosion, Tsunami, storms, wind turbulence, etc. These Mangroves has to be afforested and conserved in order to maintain a healthy ecosystem. To attain this the study of mangrove is to be done first. To classify the mangroves in its habitat, we use an algorithm from Deep Neural Network.


2014 ◽  
Vol 641-642 ◽  
pp. 1287-1290
Author(s):  
Lan Zhang ◽  
Yu Feng Nie ◽  
Zhen Hai Wang

Deep neural network as a part of deep learning algorithm is a state-of-the-art approach to find higher level representations of input data which has been introduced to many practical and challenging learning problems successfully. The primary goal of deep learning is to use large data to help solving a given task on machine learning. We propose an methodology for image de-noising project defined by this model and conduct training a large image database to get the experimental output. The result shows the robustness and efficient our our algorithm.


2019 ◽  
Vol 28 (12) ◽  
pp. 1950153 ◽  
Author(s):  
Jing Tan ◽  
Chong-Bin Chen

We use the deep learning algorithm to learn the Reissner–Nordström (RN) black hole metric by building a deep neural network. Plenty of data are determined in boundary of AdS and we propagate them to the black hole horizon through AdS metric and equation of motion (e.o.m). We label these data according to the values near the horizon, and together with initial data they constitute a data set. Then we construct corresponding deep neural network and train it with the data set to obtain the Reissner–Nordström (RN) black hole metric. Finally, we discuss the effects of learning rate, batch-size and initialization on the training process.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_4) ◽  
Author(s):  
Shirin Hajeb Mohammadalipour ◽  
Alicia Cascella ◽  
Matt Valentine ◽  
K.H. Chon

The ability of an automatic external defibrillator (AED) to make a reliable shock decision during cardio pulmonary resuscitation (CPR) would improve the survival rate of patients with out-of-hospital cardiac arrest. Since chest compressions induce motion artifacts in the electrocardiogram (ECG), current AEDs instruct the user to stop CPR while an automated rhythm analysis is performed. It has been shown that minimizing interruptions in CPR increases the chance of survival. While deep learning approaches have been used successfully for arrhythmia classification, their performance has not been evaluated for creating an AED shock advisory system that can coexist with CPR. To this end, the objective of this study was to apply a deep-learning algorithm using convolutional layers and residual networks to classify shockable versus non-shockable rhythms in the presence and absence of CPR artifact using only the ECG data. The feasibility of the deep learning method was validated using 8-sec segments of ECG with and without CPR. Two separate databases were used: 1) 40 subjects’ data without CPR from Physionet with 1131 shockable and 2741 non-shockable classified recordings, and 2) CPR artifacts that were acquired from a commercial AED during asystole delivered by 43 different resuscitators. For each 8-second ECG segment, randomly chosen CPR data from 43 different types were added to it so that 5 non-shockable and 10 shockable CPR-contaminated ECG segments were created. We used 30 subjects’ and the remaining 10 for training and test datasets, respectively, for the database 1). For the database 2), we used 33 and 10 subjects’ data for training and testing, respectively. Using our deep neural network model, the sensitivity and specificity of the shock versus no-shock decision for both datasets using the four-fold cross-validation were found to be 95.21% and 86.03%, respectively. For shockable versus non-shockable classification of ECG without CPR artifact, the sensitivity was 99.04% and the specificity was 95.2%. A sensitivity of 94.21% and a specificity of 86.14% were obtained for ECG with CPR artifact. These results meet the AHA sensitivity requirement (>90%).


Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 652 ◽  
Author(s):  
Carlo Augusto Mallio ◽  
Andrea Napolitano ◽  
Gennaro Castiello ◽  
Francesco Maria Giordano ◽  
Pasquale D'Alessio ◽  
...  

Background: Coronavirus disease 2019 (COVID-19) pneumonia and immune checkpoint inhibitor (ICI) therapy-related pneumonitis share common features. The aim of this study was to determine on chest computed tomography (CT) images whether a deep convolutional neural network algorithm is able to solve the challenge of differential diagnosis between COVID-19 pneumonia and ICI therapy-related pneumonitis. Methods: We enrolled three groups: a pneumonia-free group (n = 30), a COVID-19 group (n = 34), and a group of patients with ICI therapy-related pneumonitis (n = 21). Computed tomography images were analyzed with an artificial intelligence (AI) algorithm based on a deep convolutional neural network structure. Statistical analysis included the Mann–Whitney U test (significance threshold at p < 0.05) and the receiver operating characteristic curve (ROC curve). Results: The algorithm showed low specificity in distinguishing COVID-19 from ICI therapy-related pneumonitis (sensitivity 97.1%, specificity 14.3%, area under the curve (AUC) = 0.62). ICI therapy-related pneumonitis was identified by the AI when compared to pneumonia-free controls (sensitivity = 85.7%, specificity 100%, AUC = 0.97). Conclusions: The deep learning algorithm is not able to distinguish between COVID-19 pneumonia and ICI therapy-related pneumonitis. Awareness must be increased among clinicians about imaging similarities between COVID-19 and ICI therapy-related pneumonitis. ICI therapy-related pneumonitis can be applied as a challenge population for cross-validation to test the robustness of AI models used to analyze interstitial pneumonias of variable etiology.


Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1615
Author(s):  
Ines P. Nearchou ◽  
Hideki Ueno ◽  
Yoshiki Kajiwara ◽  
Kate Lillard ◽  
Satsuki Mochizuki ◽  
...  

The categorisation of desmoplastic reaction (DR) present at the colorectal cancer (CRC) invasive front into mature, intermediate or immature type has been previously shown to have high prognostic significance. However, the lack of an objective and reproducible assessment methodology for the assessment of DR has been a major hurdle to its clinical translation. In this study, a deep learning algorithm was trained to automatically classify immature DR on haematoxylin and eosin digitised slides of stage II and III CRC cases (n = 41). When assessing the classifier’s performance on a test set of patient samples (n = 40), a Dice score of 0.87 for the segmentation of myxoid stroma was reported. The classifier was then applied to the full cohort of 528 stage II and III CRC cases, which was then divided into a training (n = 396) and a test set (n = 132). Automatically classed DR was shown to have superior prognostic significance over the manually classed DR in both the training and test cohorts. The findings demonstrated that deep learning algorithms could be applied to assist pathologists in the detection and classification of DR in CRC in an objective, standardised and reproducible manner.


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