scholarly journals Full-Field Viscoelastic Inflation Response of Bovine Cornea

Author(s):  
B. L. Boyce ◽  
T. D. Nguyen ◽  
R. E. Jones

Most previous experimental studies and mechanical cornea models have ignored time-dependence of the cornea’s modulus, with only a few notable exceptions [1–3]. The purpose of the present work was to evaluate the time-dependent properties of cornea tissue independent of scleral contributions in a condition that is as physiologically-relevant as possible without resorting to costly and difficult in vivo characterization. A non-contact 3-dimensional displacement mapping tool was employed to image the entire deformation field across the entire cornea in real-time during pressurization. Unlike prior inflation-based studies, the present study’s unique approach permits dynamic real-time full-field mapping of deformation during inflation for the examination of viscoelasticity, isotropy, and homogeneity.


2016 ◽  
Vol 41 (10) ◽  
pp. 1973-1979 ◽  
Author(s):  
Zhu Wang ◽  
Wei Wang ◽  
Guang-Jian Liu ◽  
Zheng Yang ◽  
Li-Da Chen ◽  
...  




2015 ◽  
Vol 50 (7) ◽  
pp. 443-448 ◽  
Author(s):  
Rami Nachabé ◽  
Benno H.W. Hendriks ◽  
Ross Schierling ◽  
Jasmine Hales ◽  
Judy M. Racadio ◽  
...  


2005 ◽  
Vol 18 (10) ◽  
pp. 1030-1036 ◽  
Author(s):  
James Pemberton ◽  
Xiaokui Li ◽  
Antoinette Kenny ◽  
Crispin H. Davies ◽  
Mary S. Minette ◽  
...  


Author(s):  
Stefan Muench ◽  
Mike Roellig ◽  
Daniel Balzani

AbstractThis paper proposes a new method for in vivo and almost real-time identification of biomechanical properties of the human cornea based on non-contact tonometer data. Further goal is to demonstrate the method’s functionality based on synthetic data serving as reference. For this purpose, a finite element model of the human eye is constructed to synthetically generate full-field displacements from different data sets with keratoconus-like degradations. Then, a new approach based on the equilibrium gap method combined with a mechanical morphing approach is proposed and used to identify the material parameters from virtual test data sets. In a further step, random absolute noise is added to the virtual test data to investigate the sensitivity of the new approach to noise. As a result, the proposed method shows a relevant accuracy in identifying material parameters based on full-field displacements. At the same time, the method turns out to work almost in real time (order of a few minutes on a regular workstation) and is thus much faster than inverse problems solved by typical forward approaches. On the other hand, the method shows a noticeable sensitivity to rather small noise amplitudes rendering the method not accurate enough for the precise identification of individual parameter values. However, analysis show that the accuracy is sufficient for the identification of property ranges which might be related to diseased tissues. Thereby, the proposed approach turns out promising with view to diagnostic purposes.



Author(s):  
Thien Luan Phan ◽  
Nguyen Van Hieu ◽  
Tzong Shiun Li ◽  
Ko‐Chang Tsao ◽  
Congo Tak Shing Ching






Author(s):  
Peng Xiao ◽  
Viacheslav Mazlin ◽  
A. Claude Boccara ◽  
Mathias Fink ◽  
Jin Yuan
Keyword(s):  


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