Material Composition Gradients and Protein Release for Tracheal Defect Repair

2013 ◽  
Author(s):  
Lindsey Ott ◽  
Cindy Vu ◽  
Ashley Farris ◽  
Robert Weatherly ◽  
Michael Detamore
Keyword(s):  
Quality Of Life ◽  
Donor Site ◽  
Donor Site Morbidity ◽  
Prosthetic Material ◽  
Tracheal Defect ◽  
Laryngotracheal Reconstruction ◽  
Augmentation Techniques ◽  
Defect Repair ◽  
Composition Gradients

Windpipe defects result in decreased quality of life for the patient, making breathing, speaking, and swallowing difficult. Disorders of the trachea requiring intervention methods not adequately treated by slide tracheoplasty or cartilage augmentation necessitate the use of prosthetic material to expand the trachea. Furthermore, some donor site morbidity occurs with augmentation techniques and size or shape mismatches are not uncommon. Tissue engineering has the potential to create effective replacement trachea-like tissue for procedures like laryngotracheal reconstruction and may circumvent these problems.

Analysis of patient satisfaction and donor-site morbidity after different types of breast reconstruction

2014 ◽  
Vol 103 (4) ◽  
pp. 249-255 ◽  
Author(s):  
H. C. Benditte-Klepetko ◽  
F. Lutgendorff ◽  
T. Kästenbauer ◽  
M. Deutinger ◽  
C. M. A. M. van der Horst
Keyword(s):  
Quality Of Life ◽  
Patient Satisfaction ◽  
Breast Reconstruction ◽  
Latissimus Dorsi ◽  
Donor Site ◽  
Perforator Flap ◽  
Donor Site Morbidity ◽  
Deep Inferior Epigastric Perforator ◽  
Types Of Breast Reconstruction

Background and Aims: Breast reconstruction has been shown to improve quality of life. However, factors involved in long-term patient satisfaction are largely unknown. Our aim was to evaluate patient satisfaction and donor-site morbidity in five types of breast reconstruction. Material and Methods: A prospectively collected database of all breast surgery patients at Hospital Rudolfstiftung, Vienna, Austria, was searched for five types of breast reconstruction (2000–2006): implant, latissimus dorsi-flap, latissimus dorsi-flap with implant, free transverse rectus abdominis musculocutaneous-flap, and deep inferior epigastric perforator-flap. Patients were sent a study-specific questionnaire to assess satisfaction. Short-form 36-item health survey was used to analyze (quality of life), and complication data were retrieved from the database and assessed during a follow-up visit. Results: There were 257 patients identified, of whom, 126 responded to the survey (17 implant, 5 latissimus dorsi + implant, 64 latissimus dorsi, 22 transverse rectus abdominis musculocutaneous, and 18 deep inferior epigastric perforator reconstructions). No statistical differences were found in complication or reoperation rates. Deep inferior epigastric perforator–flap patients were significantly more satisfied compared to patients from the implant group ( p = 0.007). However, there was no significant difference regarding quality of life scores among the groups. After logistic regression analysis, only “impairment on daily life” showed to be independently correlated with patient satisfaction. This contrary to both operation type and complication rate which did not correlate with patient satisfaction. Conclusions: Our results indicate that operation type, complication rate, and revision rate did not independently correlate with patient satisfaction. Therefore, to further improve patient satisfaction, future research should be focused on other pro-operative factors, for example, patient education, expectations, and personality characteristics.

scholarly journals Donor-Site Morbidity after Fibula Transplantation in Head and Neck Tumor Patients: A Split-Leg Retrospective Study with Focus on Leg Stability and Quality of Life

Cancers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2217 ◽  
Author(s):  
Sameh Attia ◽  
Jonas Diefenbach ◽  
Daniel Schmermund ◽  
Sebastian Böttger ◽  
Jörn Pons-Kühnemann ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Donor Site ◽  
Donor Site Morbidity ◽  
Published Data ◽  
Complication Rates ◽  
Free Fibula Flap ◽  
Test Procedures ◽  
Fibula Flap ◽  
The Stability

The free fibula flap has been one of the most important microvascular grafts for orofacial reconstruction for more than 30 years. The complication rates at the donor-site reported in literature are considered to be low, but the published data vary greatly in some cases. In particular, restrictions in the stability and balance of the involved leg and their effects on the quality of life have been described very inconsistently to date. Therefore, this study mainly focuses on the stability and balance of the affected leg in a split-leg design. Between December 2014 and January 2018, out of 119 subjects who underwent mainly jaw ablative tumor surgery and reconstruction using a fibula flap, 68 subjects were examined for donor site morbidity. Besides reporting general types of complications, two specific test procedures were used. The Star Excursion Balance Test (SEBT) as a practical test for ankle function and the Foot and Ankle Disability Index (FADI) as a questionnaire in order to assess quality of life, depending on the lower leg function. SEBT revealed an average of 55.3 cm with the operated leg as the supporting leg, which corresponds to 95.5% of 57.9 cm achieved with the healthy leg as the supporting leg. An average FADI score of 89.4% was recorded. SEBT and FADI seem to be suitable methods of examination for subjects post fibular transplantation and pointed out minimal limitations of the involved legs in comparison to the unaffected legs. These limitations were clinically not relevant and they had minor influence on the subjects’ quality of life and their daily activities.

Full cheek defect reconstruction using ALTF versus RFF: Comparison of quality of life, clinical results, and donor site morbidity

Oral Diseases ◽  
2020 ◽  
Vol 26 (6) ◽  
pp. 1157-1164
Author(s):  
Bin Zhou ◽  
Juankun Liao ◽  
Chuandong Zhu ◽  
Kaifang Yuan ◽  
Zhixin Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Donor Site ◽  
Clinical Results ◽  
Donor Site Morbidity ◽  
Defect Reconstruction ◽  
Cheek Defect

Quality of Life and Voice Outcomes after Thyroid Ala Graft Laryngotracheal Reconstruction in Young Children

2011 ◽  
Vol 144 (5) ◽  
pp. 770-777 ◽  
Author(s):  
Yamilet Tirado ◽  
Neil K. Chadha ◽  
Jennifer Allegro ◽  
Vito Forte ◽  
Paolo Campisi
Keyword(s):  
Quality Of Life ◽  
Young Children ◽  
Laryngotracheal Reconstruction

scholarly journals Temporoparietal Fascia Free Flap for a Large Nasal Septal Perforation

2019 ◽  
Vol 04 (01) ◽  
pp. e42-e46
Author(s):  
Nicholas G. Cuccolo ◽  
Ryan P. Cauley ◽  
Brady A. Sieber ◽  
Syed M.D. Hussain ◽  
Laurel K. Chandler ◽  
...  
Keyword(s):  
Medical Condition ◽  
Donor Site ◽  
Free Tissue Transfer ◽  
Donor Site Morbidity ◽  
Nasal Septal Perforation ◽  
Temporoparietal Fascia ◽  
Versatile Tool ◽  
Underlying Medical Condition

AbstractReconstruction of large nasal septal perforations can be a considerable challenge for surgeons. Reconstructive modalities are often determined by the size of the defect and the quality of local tissue and vasculature. Local and regional flaps may not provide enough tissue to achieve successful closure in patients with large perforations and those with baseline compromise of the nasal mucosa and blood supply from prior intervention or underlying medical condition. Microvascular free tissue transfer is a possible approach to reconstruction in these patients. We report a case of a 30-year-old man who presented with a large, symptomatic, 4 × 3.5 cm perforation as a result of prior functional septoplasty at an outside hospital. Reconstruction of the defect was accomplished in this setting with a free temporoparietal fascia (TPF) flap anastomosed to the columellar branch of the labial artery and the angular vein. Postoperative follow-up visits showed successful closure of the perforation without complications. As illustrated by this case, TPF flap is a versatile tool for complex nasal reconstructions. With minimal donor-site morbidity and rich vascularity capable of promoting remucosalization without the need for prelamination, the TPF flap may be suited for the repair of large nasoseptal perforations.

scholarly journals Survival and Quality of Life after Cardiac Reoperations for Replacement of Infected Prosthetic Material

2018 ◽  
Vol 66 (S 01) ◽  
pp. S1-S110
Author(s):  
A. Hoffmeier ◽  
C. Werner ◽  
J. Sindermann ◽  
A. Rukosujew ◽  
M. Scherer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prosthetic Material
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