scholarly journals Application of three-dimensional ultrasonography (3D ultrasound) to pretreatment evaluation of plastic induration of the penis (Peyronie’s disease)

2020 ◽  
Vol 22 (2) ◽  
pp. 159
Author(s):  
Janusz Ferdynand Tyloch ◽  
Dominik Janusz Tyloch ◽  
Jan Adamowicz ◽  
Patryk Warsiński ◽  
Adam Ostrowski ◽  
...  

Aim: Peyronie’s disease (PD) or plastic induration of the penis, require complete evaluation of plaques in order to decide the best therapeutic option for patient. The purpose of this study is to compare the findings of three-dimensional ultrasound (3D US) and two-dimensional ultrasound (2D US) in patients with PD.Materials and methods: Twenty patients with PD aged 30 to 72 years were included in study. The examination was performed with a 12 MHz linear probe, using 2D US and 3D US. Localization and size of plaques were determined and time needed for imagine acquisition was determined in every case.Results: 3D ultrasound permits the visualization of the entire plaque in the coronal plane of plaque with its precise measurements. No statistical difference in plaque dimensions and its surface area assessment using 3D US and 2D US was found (127.72 mm² vs. 128.74 mm², p>0.05). The possibility to perform detailed analysis of the acquired images using generated digital cube reduced the average duration of the acquisition to 69.8 seconds (median 64 seconds) for 3D US vs. 151.25 seconds (median 145.5 seconds) for 2D US (p<0.05). A supplementary plaque was detected using 3D US.Conclusions: 3D US seems to be a valuable complement of 2D US for patients with PD. The acquisition time is significantly reduced using 3D US comparing to 2D US and thus it is more comfortable for the patient.

2019 ◽  
Vol 11 ◽  
pp. 175628721983813
Author(s):  
Robert Valenzuela ◽  
Matthew Ziegelmann ◽  
Sam Tokar ◽  
Joel Hillelsohn

Peyronie’s disease is a disorder of abnormal and dysregulated wound healing leading to scar formation in the tunica albuginea of the penis. Penile traction therapy has emerged as an attractive therapeutic option for men with Peyronie’s disease in both the acute and chronic phases. Currently, clinical studies are limited by lack of randomization, small cohorts, and lack of patient compliance with therapy. Despite these shortcomings, studies have shown a potential benefit with minimal morbidity. Specifically, penile traction may help to preserve or increase penile length and reduce penile curvature when used as monotherapy or as adjuvant therapy for surgical and intralesional treatments. Further study is necessary to define patient characteristics that are predictive of improved outcomes, determine the duration of treatment needed for clinical effect, and improve patient compliance.


2019 ◽  
Vol 21 (4) ◽  
pp. 389
Author(s):  
Philipp Seifert ◽  
Thomas Winkens ◽  
Leonard Knichel ◽  
Chirstian Kühnel ◽  
Martin Freesmeyer

Aims: To investigate the feasibility and accuracy of 3D-US extended field of view volumetric analyses acquired with mechanically-swept ultrasound probes with different measurement methods for large volume thyroid phantoms.Materials and methods: Fifteen thyroid phantoms with different shapes (regular, nodular, thickened isthmus) and volumes (50-400 mL) were created. Two different mechanically-swept US probes were used for the separate scanning of the left and right lobes: convex and linear probe. After specific modifications, the 3D-US datasets were stitched together to an extended field of view using predefined landmarks. Volumetric analyses were performed by conventional ellipsoid model and manual tracing methods. The correspondence of measured and reference volumes was calculated using Pearson’s correlation coefficients and limits of agreement according to Bland and Altman.Results: The C-probe proved feasible for the acquisition and processing of the three-dimensional ultrasound extended field of view images; very high levels of agreement (correlation coefficients for volume analyses: 0.9843-0.9992) were observed for all shapes and volumes investigated. The manual tracing method showed superior results in comparison to the ellipsoid model, but was more time consuming. The linear probe was only applicable for the 50 mL phantoms due to its limited field of view.Conclusions: The investigated mechanically-swept convex probe was suitable for the three-dimensional ultrasound extended field of view stitching of large volume thyroid phantoms. Accurate volume analyses could be carried out. The mechanically-swept linear probe is limited to a maximum of 50 m


2018 ◽  
Vol 6 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Mohamad Habous ◽  
Alaa Tealab ◽  
Mohammed Farag ◽  
Tarek Soliman ◽  
Ben Williamson ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Ralf Herwig ◽  
Manfred Bayerl

Peyronie’s disease is a connective tissue disorder in the soft tissue of the penis. The underlying cause of Peyronie’s disease is not well understood but is thought to be caused by trauma or injury to the penis during sexual intercourse. The purpose of the interdisciplinary cooperation between urological surgery and physics is the development of a physical simulation tool in order to give prognosis of possible tunica albuginea fibre rupture at a certain degree of deviation of the penis. For our group the first challenge was to translate the human organ of the penis into a physical model. Starting and marginal parameters had to be defined, whereby some of them had to be based on assumption, as physical data of the human living tissue have rarely been measured up to now. The algorithm and its dependencies had to be developed. This paper is a first step of a three-dimensional mathematical-physical simulation with the assumption of a 100% filled rigid penis. The calculation gives proof of the hypothesis that the fibre-load-angle of the penis is less than 12 degrees. Thus physical simulation is able to provide the surgeon with a simple instrument to calculate and forecast the risk of the individual patient.


2017 ◽  
Vol 14 (6) ◽  
pp. 829-833 ◽  
Author(s):  
Ezra J. Margolin ◽  
Carrie M. Mlynarczyk ◽  
John P. Mulhall ◽  
Doron S. Stember ◽  
Peter J. Stahl

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Ezra Margolin ◽  
Carrie Mlynarczyk ◽  
Doron Stember ◽  
Peter Stahl

2005 ◽  
Vol 173 (4S) ◽  
pp. 287-287
Author(s):  
Thomas X. Minor ◽  
Guiting Lin ◽  
Amr Jad ◽  
Ching-Shwun Lin ◽  
Narihiko Hayashi ◽  
...  

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