SU-E-T-08: A Beam Source Model for Monte Carlo Simulations of a Double-Scattering Proton Beam Delivery System Using Beam Current Modulation

2015 ◽  
Vol 42 (6Part11) ◽  
pp. 3332-3332
Author(s):  
J Shin ◽  
T E Merchant ◽  
S Lee ◽  
Z Li ◽  
D Shin ◽  
...  
2010 ◽  
Vol 56 (1) ◽  
pp. 153-163 ◽  
Author(s):  
Se Byeong Lee ◽  
Jungwook Shin ◽  
Dongwook Kim ◽  
Young Kyung Lim ◽  
Sunghwan Ahn ◽  
...  

2008 ◽  
Vol 35 (6Part14) ◽  
pp. 2801-2801
Author(s):  
Jungwook Shin ◽  
Jungwon Kwak ◽  
Dong Wook Kim ◽  
Dongho Shin ◽  
Myongguen Yoon ◽  
...  

2009 ◽  
Vol 37 (1) ◽  
pp. 154-163 ◽  
Author(s):  
Michael T. Gillin ◽  
Narayan Sahoo ◽  
Martin Bues ◽  
George Ciangaru ◽  
Gabriel Sawakuchi ◽  
...  

2010 ◽  
Vol 55 (23) ◽  
pp. 7081-7096 ◽  
Author(s):  
G Coutrakon ◽  
N Wang ◽  
D W Miller ◽  
Y Yang

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1889
Author(s):  
Arthur Bongrand ◽  
Charbel Koumeir ◽  
Daphnée Villoing ◽  
Arnaud Guertin ◽  
Ferid Haddad ◽  
...  

Proton therapy (PRT) is an irradiation technique that aims at limiting normal tissue damage while maintaining the tumor response. To study its specificities, the ARRONAX cyclotron is currently developing a preclinical structure compatible with biological experiments. A prerequisite is to identify and control uncertainties on the ARRONAX beamline, which can lead to significant biases in the observed biological results and dose–response relationships, as for any facility. This paper summarizes and quantifies the impact of uncertainty on proton range, absorbed dose, and dose homogeneity in a preclinical context of cell or small animal irradiation on the Bragg curve, using Monte Carlo simulations. All possible sources of uncertainty were investigated and discussed independently. Those with a significant impact were identified, and protocols were established to reduce their consequences. Overall, the uncertainties evaluated were similar to those from clinical practice and are considered compatible with the performance of radiobiological experiments, as well as the study of dose–response relationships on this proton beam. Another conclusion of this study is that Monte Carlo simulations can be used to help build preclinical lines in other setups.


2011 ◽  
Vol 58 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Kyong Sei Lee ◽  
Byungsik Hong ◽  
Sung Keun Park ◽  
Han Bum Rhee ◽  
Kwang-Souk Sim

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