Effects of Caffeine Ingestion on Exercise-induced Change during High-Intensity Intermittent Exercise

1995 ◽  
Vol 5 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Isaiah Trice ◽  
Emily M. Haymes

In this study a double-blind design was used to determine the effect of caffeine on time to exhaustion and on associated metabolic and circulatory measures. Eight male subjects ingested either caffeine (5 mg/kg body weight) or a placebo 1 hr prior to exercise at 85-90% of maximum workload. Subjects were encouraged to complete three 30-min intermittent cycling periods at 70 rpm with 5 min rest between each. The exercise was terminated when the subject failed to complete three 30-min periods or failed to maintain 70 rpm for at least 15 s consecutively. Serum free fatty acids, glycerol, blood glucose, lactate, perceived exertion, heart rate, andcost were measured. The time to exhaustion was significantly longer during the caffeine trial than during the placebo trial. Serum free fatty acid levels were significantly different between trials. The decline in blood glucose levels was significantly less during the caffeine trial than during the placebo trial. There were no significant differences between trials for the other measures. It was concluded that caffeine increases time to exhaustion when trained subjects cycled intermittently at high levels of intensity.

1992 ◽  
Vol 2 (4) ◽  
pp. 317-327 ◽  
Author(s):  
Randall L. Wilber ◽  
Robert J. Moffatt

Ten trained male runners performed a treadmill exercise test at 80%under two experimental conditions, carbohydrate (CHO, 7% carbohydrate) and placebo (P), to determine the effect of carbohydrate ingestion on endurance performance (treadmill run time), blood glucose concentration, respiratory exchange ratio (RER), and subjective ratings of perceived exertion (RPE). Treatment order was randomized and counterbalanced and test solutions were administered double-blind. Ingestion took place 5 min preexercise (250 ml) and at 15-min intervals during exercise (125 ml). Performance was enhanced by 29.4% (p~ 0.05) during CHO (115 ±25 min) compared to P (92 ± 27 min). Blood glucose concentration was significantly greater during CHO (5.6 ± 0.9 mM) relative to P (5.0 ±0.7 mM). There was a significant increase in mean RER following CHO ingestion (.94±.01) compared to P (.90±.01). Average RPE was significantly less during CHO (14.5±2.3) relative to P (15.4±2.4). These data suggest that time to exhaustion of high-intensity treadmill exercise is delayed as a result of carbohydrate ingestion and that this effect is mediated by favorable alterations in blood glucose concentration and substrate utilization.


1992 ◽  
Vol 2 (3) ◽  
pp. 272-286 ◽  
Author(s):  
Ian P. Snider ◽  
Terry L. Bazzarre ◽  
Scott D. Murdoch ◽  
Allan Goldfarb

This study examined the effects of the Coenzyme Athletic Performance System (CAPS) on endurance performance to exhaustion. CAPS contains 100 mg coenzyme Q10,500 mg cytochrome C, 100 mg inosine, and 200 IU vitamin E. Eleven highly trained male triathletes were given three daily doses of either CAPS or placebo (dicalcium phosphate) for two 4-week periods using a double-blind crossover design. A 4-week washout period separated the two treatment periods. An exhaustive performance test, consisting of 90 minutes of running on a treadmill (70%) followed by cycling (70%) until exhaustion, was conducted after each treatment period. The mean (±SEM) time to exhaustion for the subjects using CAPS (223 ±17 min) was not significantly different (p=0.57) from the placebo trial (215 ±9 min). Blood glucose, lactate, and free fatty acid concentrations at exhaustion did not differ between treatments (p< 0.05). CAPS had no apparent benefit on exercise to exhaustion.


2017 ◽  
Vol 29 (3) ◽  
pp. 336-340 ◽  
Author(s):  
Camilla Astley ◽  
Diego Souza ◽  
Marcos Polito

Purpose:To compare the acute effect of caffeine ingestion on performance in young judo athletes.Method:In a randomized double-blind design, eighteen judo athletes (16.1 ± 1.4 yrs.) were evaluated on three nonconsecutive days. On the first day, the special judo fitness test (SJFT) was used as a control session. On the second day, the sample was randomly divided into two equal groups. One group received 4 mg.kg-1 of caffeine (capsule) and the other group received a placebo. After resting for 60 min, the sample performed the SJFT. On the final day of testing, the same procedure was performed but the substance ingested was exchanged between the groups.Results:Heart rate (HR) and rating of perceived exertion (RPE) were recorded throughout the applications of the SJFTs. Caffeine ingestion did not induce changes in HR, but reduced the RPE compared with the placebo session (7.0 ± 1.1 vs 8.2 ± 2.0; p < .05), increased the number of throws applied (29.0 ± 2.6 vs 22.1 ± 3.4; p < .01) and reduced the SJFT index (12.2 ± 0.5 vs. 15.7 ± 0.9; p < .001).Conclusion:4 mg.kg-1 did not alter HR but improved performance on SJFT in young judo athletes and reduced the RPE.


1995 ◽  
Vol 20 (2) ◽  
pp. 168-177 ◽  
Author(s):  
Brian Robert MacIntosh ◽  
Bridget Margarette Wright

The purpose of this study was to evaluate the potential ergogenic benefit of caffeine in the performance of a 1,500-meter swim. Caffeine (6 mg∙kg−1) or placebo was administered 2-1/2 hrs prior to the swim trial in a double-blind crossover design. Caffeine resulted in a significantly lower perceived exertion for 100-m warm-up swims. Subjects swam significantly (p < 0.05) faster with caffeine (20:58.8 ± 0:36.4, mean ± SEM) than without (21:21.8 ± 0:38). Plasma potassium was significantly lower prior to the swim with caffeine, and blood glucose was higher after that swim. Caffeine provides an ergogenic benefit for a 1,500-meter swim, an event that is completed in less than 25 min. Lower plasma potassium concentration prior to exercise and higher blood glucose following the trial suggest that electrolyte balance and glucose availability may be important aspects of the ergogenic effects of caffeine. Key words: methylxanthines, endurance, exercise, potassium, fatigue, swimming


Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1422 ◽  
Author(s):  
Arthur de Azevedo ◽  
Mauro Guerra ◽  
Leonardo Caldas ◽  
Lucas Guimarães-Ferreira

Mixed martial arts (MMA) is a combat sport where competitors utilize strikes (punches, kicks, knees, and elbows) and submission techniques to defeat opponents in a cage or ring. The aim of this study was to investigate the effect of acute caffeine ingestion on punching performance by professional MMA athletes. The study used a double-blind, counterbalanced, crossover design. Eleven professional MMA competitors (27.6 ± 4.3 years and 83.5 ± 7.8 kg of body weight) ingested a dose of caffeine (5 mg·kg−1) or placebo 60 min prior to three sets of punching. Each set consisted of 15 s, at which participants were asked to perform straight punches with maximum strength and frequency with his dominant arm. After each set, a 45 s recovery time was applied. Using a force transducer attached to a cushioned plate, the punch frequency, and mean and maximal punch force was measured. The readiness to invest in both physical (RTIPE) and mental (RTIME) effort was assessed prior to the protocol, and the rating of perceived exertion (RPE) was recorded after. Caffeine ingestion did not result in increased punching frequency, mean and maximum punch force, RTIPE, RTIME, and RPE when compared to the placebo condition. Based on these results, acute caffeine ingestion did not improve punching performance in professional MMA athletes.


2019 ◽  
Vol 126 (3) ◽  
pp. 515-529
Author(s):  
Marina Saldanha da Silva Athayde ◽  
Rafael L. Kons ◽  
Daniele Detanico

This study analyzed the effects of caffeine ingestion during judo matches on judo athletes' match-derived performance and perceived exertion responses. We applied a double-blind randomized crossover (caffeine vs. placebo conditions) research design. Twelve male athletes performed three 5-minute matches separated by 15 minutes of passive rest. Immediately after each match, the athletes completed ratings of perceived exertion (RPEs), and one minute before beginning the second and third matches, they provided ratings of perceived recovery (RPRs). We filmed all matches for subsequent analysis of the athletes' technical skills. We found no interaction between condition and time of RPE, RPR, and match-derived technical variables, but number of attacks and RPR decreased over the matches, and RPE increased in both conditions. Three participants showed individual positive responses to caffeine ingestion for number of attacks. Attacks, efficiency, and effectiveness presented low sensitivity in both conditions, as only large changes could be identified. We conclude that caffeine ingestion did not provoke changes in either perceived exertion or match-derived performance. Match-derived technical variables were not sensitive for detecting small or medium effects of caffeine, but perceived exertion may detect at least medium effect after caffeine ingestion.


2000 ◽  
Vol 10 (2) ◽  
pp. 170-181 ◽  
Author(s):  
John P. Warber ◽  
John F. Patton ◽  
William J. Tharion ◽  
Steven H. Zeisel ◽  
Robert P. Mello ◽  
...  

It has been reported that plasma choline levels decrease following certain types of strenuous exercise. Preliminary findings also suggest that a drop in plasma choline may limit physical performance, while choline supplementation may delay fatigue during prolonged efforts. A double-blind crossover design was used to determine the relationship between plasma choline and performance during and after 4 hr of strenuous exercise. Volunteers (N = 14) received either a placebo or treatment beverage (8.425 g choline citrate) prior to and midway through a 4-hr load carriage treadmill exercise (3% grade at 5.6 km/h × 20 km) carrying a total load of 34.1 kg. Following the treadmill test, run time-to-exhaustion and squat tests were performed, and perceived exertion, plasma choline, glycerophosphocholine, and phosphatidylcholine were measured. Plasma choline levels increased 128% after the run-to-exhaustion with the choline supplemented beverage but remained unchanged with the placebo beverage. No significant effects were seen with choline supplementation on any outcome performance measure. Consequently, soldiers conditioned to carry heavy loads over long distances do not deplete plasma choline as a result of a prolonged exhaustive exercise under a placebo beverage, nor do they benefit from choline supplementation to delay fatigue under the same conditions.


1994 ◽  
Vol 76 (6) ◽  
pp. 2461-2466 ◽  
Author(s):  
C. M. Cupido ◽  
A. L. Hicks ◽  
R. S. McKelvie ◽  
D. G. Sale ◽  
A. J. McComas

The effects of beta-blockade on skeletal muscle excitability and fatiguability during exercise were examined. Ten healthy males (mean age 21.9 +/- 1.1 yr) performed a 4-min fatigue protocol consisting of intermittent isometric voluntary contractions of the knee extensors in one leg. Subjects performed the exercise after treatment with placebo, 100 mg metoprolol, or an equipotent dose of propranolol (60 mg, n = 1; 80 mg, n = 8; 100 mg, n = 1) twice a day for 76 h before testing according to a randomized double-blind design. The evoked twitch torque, maximal voluntary torque, and maximal M-wave amplitude were unaffected by the beta-blockade treatments before fatigue. During the placebo trial, there were significant reductions in the evoked and voluntary torques (77 +/- 15 and 55 +/- 11%, respectively) after the fatigue protocol; however, both the voluntary electromyogram and evoked M waves were well maintained throughout fatigue. The beta-blockade treatments had no significant effect on torque or electromyogram activity over the course of the exercise. Thus, despite evidence for an impairment of dynamic exercise performance with beta 1- and beta 1,2-blockade, there appears to be no effect of these agents on muscle excitability and fatiguability during isometric muscle activity.


Author(s):  
Rodrigo De Araujo Bonetti De Poli ◽  
Willian Eiji Miyagi ◽  
Fabio Yuzo Nakamura ◽  
Alessandro Moura Zagatto

The aim of the current study was to investigate the effects of acute caffeine supplementation on anaerobic capacity determined by the alternative maximal accumulated oxygen deficit (MAODALT) in running effort. Eighteen recreational male runners [29 ± 7years; total body mass 72.1 ± 5.8 kg; height 176.0 ± 5.4cm; maximal oxygen uptake (VO2max) 55.8 ± 4.2 ml·kg-1 ·min-1] underwent a graded exercise test. Caffeine (6 mg·kg-1) or a placebo were administered 1 hr before the supramaximal effort at 115% of the intensity associated with VO2max in a double-blind, randomized cross-over study, for MAODALT assessment. The time to exhaustion under caffeine condition (130.2 ± 24.5s) was 11.3% higher (p = .01) than placebo condition (118.8 ± 24.9 s) and the qualitative inference for substantial changes showed a very likely positive effect (93%). The net participation of the oxidative phosphorylation pathway was significantly higher in the caffeine condition (p = .02) and showed a likely positive effect (90%) of 15.3% with caffeine supplementation. The time constant of abrupt decay of excess postexercise oxygen consumption (τ1) was significantly different between caffeine and placebo conditions (p = .03) and showed a likely negative effect (90%), decreasing -8.0% with caffeine supplementation. The oxygen equivalents estimated from the glycolytic and phosphagen metabolic pathways showed a possibly positive effect (68%) and possibly negative effect (78%) in the qualitative inference with caffeine ingestion, respectively. However, the MAODALT did not differ under the caffeine or placebo conditions (p = .68). Therefore, we can conclude that acute caffeine ingestion does not modify the MAODALT, reinforcing the robustness of this method. However, caffeine ingestion can alter the glycolytic and phosphagen metabolic pathway contributions to MAODALT.


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