Effect of Transforming Growth Factor-β Receptor I Kinase Inhibitor 2,4-Disubstituted Pteridine (SD-208) in Chronic Allergic Airway Inflammation and Remodeling

Kinase Inhibitor ◽

Allergic Airway Inflammation ◽

Nonclinical Safety Evaluation of a Transforming Growth Factor β Receptor I Kinase Inhibitor in Fischer 344 Rats and Beagle Dogs

Journal of Clinical Toxicology ◽

10.4172/2161-0495.196 ◽

2014 ◽

Vol 04 (03) ◽

Cited By ~ 3

Author(s):

Anja J Stauber Kelly M Credill

Keyword(s):

Growth Factor ◽

Kinase Inhibitor ◽

Safety Evaluation ◽

Fischer 344 Rats ◽

Beagle Dogs ◽

Fischer 344 ◽

Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling

American Journal of Respiratory and Critical Care Medicine ◽

10.1164/rccm.200706-958oc ◽

2008 ◽

Vol 177 (6) ◽

pp. 593-603 ◽

Cited By ~ 68

Author(s):

Ramzi Fattouh ◽

N. Gabriela Midence ◽

Katherine Arias ◽

Jill R. Johnson ◽

Tina D. Walker ◽

...

Keyword(s):

Growth Factor ◽

Airway Inflammation ◽

House Dust ◽

House Dust Mite ◽

Airway Remodeling ◽

Allergic Airway Inflammation ◽

Dust Mite

A Novel Transforming Growth Factor β Receptor Kinase Inhibitor, A-77, Prevents the Peritoneal Dissemination of Scirrhous Gastric Carcinoma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-1634 ◽

2008 ◽

Vol 14 (9) ◽

pp. 2850-2860 ◽

Cited By ~ 31

Author(s):

Hidemi Kawajiri ◽

Masakazu Yashiro ◽

Osamu Shinto ◽

Kazunori Nakamura ◽

Masashige Tendo ◽

...

Keyword(s):

Growth Factor ◽

Gastric Carcinoma ◽

Kinase Inhibitor ◽

Peritoneal Dissemination ◽

Receptor Kinase ◽

Scirrhous Gastric Carcinoma ◽

Transforming Growth Factor β Receptor I Kinase Inhibitor Down-Regulates Cytokine Secretion and Multiple Myeloma Cell Growth in the Bone Marrow Microenvironment

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-04-0632 ◽

2004 ◽

Vol 10 (22) ◽

pp. 7540-7546 ◽

Cited By ~ 74

Author(s):

Toshiaki Hayashi ◽

Teru Hideshima ◽

Aaron N. Nguyen ◽

Olivier Munoz ◽

Klaus Podar ◽

...

Keyword(s):

Multiple Myeloma ◽

Bone Marrow ◽

Growth Factor ◽

Cell Growth ◽

Kinase Inhibitor ◽

Myeloma Cell ◽

Multiple Myeloma Cell ◽

First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-14-1380 ◽

2014 ◽

Vol 21 (3) ◽

pp. 553-560 ◽

Cited By ~ 125

Author(s):

Jordi Rodon ◽

Michael A. Carducci ◽

Juan M Sepulveda-Sánchez ◽

Analia Azaro ◽

Emiliano Calvo ◽

...

Keyword(s):

Growth Factor ◽

Advanced Cancer ◽

Kinase Inhibitor ◽

The Novel ◽

Human Dose ◽

Dose Study ◽

Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer

Investigational New Drugs ◽

10.1007/s10637-014-0192-4 ◽

2014 ◽

Vol 33 (2) ◽

pp. 357-370 ◽

Cited By ~ 56

Author(s):

Jordi Rodón ◽

Michael Carducci ◽

Juan M. Sepulveda-Sánchez ◽

Analía Azaro ◽

Emiliano Calvo ◽

...

Keyword(s):

Growth Factor ◽

Advanced Cancer ◽

Kinase Inhibitor ◽

Phase 1 ◽

Phase 1 Study ◽

Β Receptor ◽

Biomarker Evaluation

SD-208, a Novel Transforming Growth Factor β Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells In vitro and In vivo

Cancer Research ◽

10.1158/0008-5472.can-04-1013 ◽

2004 ◽

Vol 64 (21) ◽

pp. 7954-7961 ◽

Cited By ~ 293

Author(s):

Martin Uhl ◽

Steffen Aulwurm ◽

Jörg Wischhusen ◽

Markus Weiler ◽

Jing Ying Ma ◽

...

Keyword(s):

Growth Factor ◽

Kinase Inhibitor ◽

Glioma Cells ◽

Human Glioma ◽

Human Glioma Cells ◽

Brain perfusion and permeability in patients with advanced, refractory glioblastoma treated with lomustine and the transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate

Oncology Letters ◽

10.3892/ol.2015.3106 ◽

2015 ◽

Vol 9 (6) ◽

pp. 2442-2448 ◽

Cited By ~ 5

Author(s):

JUAN SEPULVEDA-SANCHEZ ◽

ANA RAMOS ◽

AMAYA HILARIO ◽

GUILLERMO DE VELASCO ◽

DANIEL CASTELLANO ◽

...

Keyword(s):

Growth Factor ◽

Kinase Inhibitor ◽

Brain Perfusion ◽

P48. Transforming growth factor β receptor I kinase inhibitor and bisphosphonates are additive to reduce breast cancer bone metastases

Cancer Treatment Reviews ◽

10.1016/j.ctrv.2008.03.106 ◽

2008 ◽

Vol 34 ◽

pp. 37-38 ◽

Cited By ~ 1

Author(s):

Khalid Mohammad ◽

Elizabeth Stebbins ◽

Lauren Kingsley ◽

Pierrick Fournier ◽

Maria Niewolna ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Bone Metastases ◽

Kinase Inhibitor ◽

Galunisertib (LY2157299), a transforming growth factor-β receptor I kinase inhibitor, attenuates acute pancreatitis in rats

Brazilian Journal of Medical and Biological Research ◽

10.1590/1414-431x20165388 ◽

2016 ◽

Vol 49 (9) ◽

Cited By ~ 5

Author(s):

X. Liu ◽

M. Yu ◽

Y. Chen ◽

J. Zhang

Keyword(s):

Acute Pancreatitis ◽

Growth Factor ◽

Kinase Inhibitor ◽