GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer's Disease Brain and Improves Cognitive Performance in Preclinical Models

2007 ◽  
Vol 321 (3) ◽  
pp. 1032-1045 ◽  
Author(s):  
Andrew D. Medhurst ◽  
Alan R. Atkins ◽  
Isabel J. Beresford ◽  
Kim Brackenborough ◽  
Michael A. Briggs ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Receptor Antagonist ◽  
Cognitive Performance ◽  
Preclinical Models ◽  
Histamine H3 Receptors ◽  
H3 Receptor ◽  
H3 Receptors ◽  
Histamine H3

scholarly journals Characterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM mice

2009 ◽  
Vol 157 (1) ◽  
pp. 130-138 ◽  
Author(s):  
AD Medhurst ◽  
JC Roberts ◽  
J Lee ◽  
CPL-H Chen ◽  
SH Brown ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Histamine H3 Receptors ◽  
H3 Receptors ◽  
Histamine H3

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer’s disease

2020 ◽  
Vol 207 ◽  
pp. 112743
Author(s):  
Dorota Łażewska ◽  
Marek Bajda ◽  
Maria Kaleta ◽  
Paula Zaręba ◽  
Agata Doroz-Płonka ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rational Design ◽  
Receptor Ligands ◽  
Histamine H3 Receptor ◽  
H3 Receptor ◽  
Histamine H3

Search for new multi-target compounds against Alzheimer’s disease among histamine H3 receptor ligands

2020 ◽  
Vol 185 ◽  
pp. 111785 ◽  
Author(s):  
Marek Bajda ◽  
Dorota Łażewska ◽  
Justyna Godyń ◽  
Paula Zaręba ◽  
Kamil Kuder ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Receptor Ligands ◽  
Histamine H3 Receptor ◽  
H3 Receptor ◽  
Histamine H3

P3-354: ABT-288, a potent and selective histamine H3 receptor antagonist, facilitates attention and memory in preclinical models

2010 ◽  
Vol 6 ◽  
pp. S556-S556 ◽  
Author(s):  
Jorge D. Brioni ◽  
Tim Esbenshade ◽  
Kaitlin Browman ◽  
Thomas Miller ◽  
Richard Radek ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Attention And Memory ◽  
Preclinical Models ◽  
Histamine H3 Receptor ◽  
H3 Receptor ◽  
Histamine H3
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