scholarly journals P-Glycoprotein Is a Major Determinant of Norbuprenorphine Brain Exposure and Antinociception

2012 ◽  
Vol 343 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Sarah M. Brown ◽  
Scott D. Campbell ◽  
Amanda Crafford ◽  
Karen J. Regina ◽  
Michael J. Holtzman ◽  
...  
Keyword(s):  
Major Determinant ◽  
P Glycoprotein ◽  
Brain Exposure

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability

2019 ◽  
Vol 16 (9) ◽  
pp. 3842-3852 ◽  
Author(s):  
Alejandra Martínez-Chávez ◽  
Stéphanie van Hoppe ◽  
Hilde Rosing ◽  
Maria C. Lebre ◽  
Matthijs Tibben ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
P Glycoprotein ◽  
Brain Exposure

scholarly journals P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

1996 ◽  
Vol 93 (9) ◽  
pp. 4001-4005 ◽  
Author(s):  
E. G. Schuetz ◽  
A. H. Schinkel ◽  
M. V. Relling ◽  
J. D. Schuetz
Keyword(s):  
Inducible Expression ◽  
Major Determinant ◽  
P Glycoprotein ◽  
Cytochrome P4503a

Abcb1a (P-glycoprotein) limits brain exposure of the anticancer drug candidate seliciclib in vivo in adult mice

2017 ◽  
Vol 132 ◽  
pp. 232-236 ◽  
Author(s):  
Franciska Erdő ◽  
Ildikó Nagy ◽  
Beáta Tóth ◽  
Annamária Bui ◽  
Éva Molnár ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Drug Candidate ◽  
Adult Mice ◽  
P Glycoprotein ◽  
Brain Exposure

scholarly journals P-Glycoprotein on Blood-Brain Barrier Plays a Vital Role in Fentanyl Brain Exposure and Respiratory Toxicity in Rats

2018 ◽  
Vol 164 (1) ◽  
pp. 353-362 ◽  
Author(s):  
Chenchen Yu ◽  
Mei Yuan ◽  
Haiying Yang ◽  
Xiaomei Zhuang ◽  
Hua Li
Keyword(s):  
Blood Brain Barrier ◽  
Vital Role ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain ◽  
Brain Exposure ◽  
Respiratory Toxicity

scholarly journals Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration

2008 ◽  
Vol 37 (3) ◽  
pp. 529-535 ◽  
Author(s):  
Rong Zhao ◽  
J. Cory Kalvass ◽  
Souzan B. Yanni ◽  
Arlene S. Bridges ◽  
Gary M. Pollack
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain ◽  
Brain Exposure

Pharmacogenetics of Clozapine: In Vivo Role of Cytochrome P450 Isoforms and P-Glycoprotein

2008 ◽  
Vol 41 (05) ◽  
Author(s):  
E Jaquenoud-Sirot ◽  
B Knezevic ◽  
G Perla Morena ◽  
P Baumann ◽  
CB Eap
Keyword(s):  
Cytochrome P450 ◽  
P Glycoprotein ◽  
Cytochrome P450 Isoforms

Structure activity-relationships of P-Glycoprotein modulation using a small library of macrocyclic lathyrane diterpenes

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
M Reis ◽  
RJ Ferreira ◽  
MMM Santos ◽  
DJVA dos Santos ◽  
J Molnár ◽  
...  
Keyword(s):  
Structure Activity Relationships ◽  
Structure Activity ◽  
P Glycoprotein
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