NIN-like protein transcription factors regulate leghemoglobin genes in legume nodules

Science ◽  
2021 ◽  
Vol 374 (6567) ◽  
pp. 625-628
Author(s):  
Suyu Jiang ◽  
Marie-Françoise Jardinaud ◽  
Jinpeng Gao ◽  
Yann Pecrix ◽  
Jiangqi Wen ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Protein Transcription

scholarly journals Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a

2010 ◽  
Vol 78 (2) ◽  
pp. 226-236 ◽  
Author(s):  
Indira Jutooru ◽  
Gayathri Chadalapaka ◽  
Maen Abdelrahim ◽  
Md Riyaz Basha ◽  
Ismael Samudio ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Tumor Growth ◽  
Pancreatic Tumor ◽  
Specificity Protein ◽  
Protein Transcription

Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development

2018 ◽  
Vol 11 (7) ◽  
pp. 371-382 ◽  
Author(s):  
Stephen Safe ◽  
James Abbruzzese ◽  
Maen Abdelrahim ◽  
Erik Hedrick
Keyword(s):  
Transcription Factors ◽  
Drug Development ◽  
Specificity Protein ◽  
Protein Transcription

scholarly journals 1000. Down-Regulating the Epithelial Glycoprotein-2 Promoter Utilizing Engineered Zinc Finger Protein Transcription Factors

2006 ◽  
Vol 13 ◽  
pp. S385
Author(s):  
Willemijn M. Gommans ◽  
Pamela M.J. McLaughlin ◽  
Robbert Cool ◽  
Beatrice I. Lindhout ◽  
Bert van der Zaal ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Finger Protein ◽  
Protein Transcription

The Potential Role of Sterol Regulatory Element Binding Protein Transcription Factors in Renal Injury

2007 ◽  
Vol 17 (1) ◽  
pp. 62-65 ◽  
Author(s):  
Marek Szolkiewicz ◽  
Michal Chmielewski ◽  
Anna Nogalska ◽  
Ewa Stelmanska ◽  
Julian Swierczynski ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Renal Injury ◽  
Potential Role ◽  
Binding Protein ◽  
Regulatory Element ◽  
Element Binding Protein ◽  
Sterol Regulatory Element ◽  
Protein Transcription

Expression of Specificity Protein Transcription Factors in Pancreatic Cancer and their Association in Prognosis and Therapy

2012 ◽  
Vol 19 (22) ◽  
pp. 3779-3786 ◽  
Author(s):  
Umesh T. Sankpal ◽  
Pius Maliakal ◽  
Debashish Bose ◽  
Omar Kayaleh ◽  
Daniel Buchholz ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Transcription Factors ◽  
Specificity Protein ◽  
Protein Transcription

scholarly journals E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

2019 ◽  
Vol 216 (8) ◽  
pp. 1749-1761 ◽  
Author(s):  
Tejas Kadakia ◽  
Xuguang Tai ◽  
Michael Kruhlak ◽  
Jan Wisniewski ◽  
Il-Young Hwang ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Chemokine Receptor ◽  
Chemokine Receptors ◽  
Cxcr4 Expression ◽  
Receptor Expression ◽  
Thymic Epithelial Cells ◽  
E Protein ◽  
Regulated Expression ◽  
Genes Encoding ◽  
Protein Transcription

Preselection thymocytes are normally retained in the thymic cortex, but the mechanisms responsible remain incompletely understood. We now report that deletion of genes encoding the E-protein transcription factors E2A and HEB disorders chemokine receptor expression on developing thymocytes to allow escape of preselection TCR−CD8+ thymocytes into the periphery. We document that CXCR4 expression normally anchors preselection thymocytes to the thymic cortex via interaction with its ligand CXCL12 on cortical thymic epithelial cells, and that disruption of CXCR4–CXCL12 engagements release preselection thymocytes from the thymic cortex. We further document that CXCR4 expression must be extinguished by TCR-mediated positive selection signals to allow migration of TCR-signaled thymocytes out of the thymic cortex into the medulla. Thus, E-protein transcription factors regulate the ordered expression pattern of chemokine receptors on developing thymocytes, and the interaction of the chemokine receptor CXCR4 with its ligand adheres TCR-unsignaled preselection thymocytes to the thymic cortex.

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