Anthracene-Polyamine Conjugates InhibitIn VitroProliferation of Intraerythrocytic Plasmodium falciparum Parasites
2013 ◽
Vol 57
(6)
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pp. 2874-2877
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Keyword(s):
ABSTRACTAnthracene-polyamine conjugates inhibit thein vitroproliferation of the intraerythrocytic human malaria parasitePlasmodium falciparum, with 50% inhibitory concentrations (IC50s) in the nM to μM range. The compounds are taken up into the intraerythrocytic parasite, where they arrest the parasite cell cycle. Both the anthracene and polyamine components of the conjugates play a role in their antiplasmodial effect.
Keyword(s):
2011 ◽
Vol 46
(9)
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pp. 4184-4191
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1985 ◽
Vol 161
(1)
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pp. 160-180
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2000 ◽
Vol 44
(1)
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pp. 88-96
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Keyword(s):
2011 ◽
Vol 21
(19)
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pp. 6003-6006
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2015 ◽
Vol 10
(2)
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pp. 73-78
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