Decline in Sulfadoxine-Pyrimethamine-Resistant Alleles after Change in Drug Policy in the Amazon Region of Peru
2007 ◽
Vol 52
(2)
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pp. 739-741
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ABSTRACT The frequency of alleles with triple mutations conferring sulfadoxine-pyrimethamine (SP) resistance in the Peruvian Amazon Basin has declined (16.9% for dhfr and 0% for dhps compared to 47% for both alleles in 1997) 5 years after SP was replaced as the first-line treatment for Plasmodium falciparum malaria. Microsatellite analysis showed that the dhfr and dhps alleles are of common origin.
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2015 ◽
Vol 31
◽
pp. 183-189
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Keyword(s):
2004 ◽
Vol 98
(6)
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pp. 347-353
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Keyword(s):
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2020 ◽
Vol 102
(5)
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pp. 1056-1063
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Keyword(s):
2015 ◽
Vol 93
(5)
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pp. 961-966
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