scholarly journals First Whole-Genome Sequence of a Haemophilus influenzae Type e Strain Isolated from a Patient with Invasive Disease in Italy

2017 ◽  
Vol 5 (13) ◽  
Author(s):  
Maria Giufrè ◽  
Rita Cardines ◽  
Marina Cerquetti
Keyword(s):  
Haemophilus Influenzae ◽  
Genome Sequence ◽  
Invasive Disease ◽  
Whole Genome Sequence ◽  
Haemophilus Influenzae Type ◽  
Whole Genome ◽  
Type B ◽  
Genomic Information ◽  
Conjugate Vaccines ◽  
Content Type

ABSTRACT In the present era of conjugate vaccines against Haemophilus influenzae type b, non-vaccine-preventable strains are of concern. Here, we report the first whole-genome sequence of an invasive H. influenzae type e strain. This genomic information will enable further investigations on encapsulated non-type b H. influenzae strains.

scholarly journals First Complete Genome Sequence of Haemophilus influenzae Serotype a

2017 ◽  
Vol 5 (3) ◽  
Author(s):  
Mariam Iskander ◽  
Kristy Hayden ◽  
Gary Van Domselaar ◽  
Raymond Tsang
Keyword(s):  
Haemophilus Influenzae ◽  
Genome Sequence ◽  
Invasive Disease ◽  
Indigenous Populations ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Human Pathogen ◽  
Small Children ◽  
Content Type ◽  
Serotype A

ABSTRACT Haemophilus influenzae is an important human pathogen that primarily infects small children. In recent years, H. influenzae serotype a has emerged as a significant cause of invasive disease among indigenous populations. Here, we present the first complete whole-genome sequence of H. influenzae serotype a.

Haemophilus Influenzae Type B Conjugate Vaccines

1992 ◽  
Vol 26 (11) ◽  
pp. 1429-1440 ◽  
Author(s):  
Rex W. Force ◽  
Ralph A. Lugo ◽  
Milap C. Nahata
Keyword(s):  
Immune Response ◽  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Data Sources ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Conjugate Vaccines ◽  
Medline Search ◽  
Study Selection

OBJECTIVE: To review the epidemiology of Haemophilus influenzae type b (Hib) disease, the first Hib vaccine and its limitations, the characteristics and clinical efficacy of the newer conjugate vaccines, and the current recommendations for administration of Hib vaccines. DATA SOURCES: Pertinent literature was identified via a MEDLINE search. Additionally, references cited in published articles were used as data sources. STUDY SELECTION: Studies describing the epidemiology of Hib disease and the efficacy and/or immunogenicity of the Hib vaccines are reviewed. DATA SYNTHESIS: Serious invasive disease secondary to Hib infection causes significant morbidity and mortality in children between the ages of three months and five years. The original Hib vaccine was found to be ineffective in stimulating an adequate immune response in children younger than two years of age. The new Hib conjugate vaccines provide superior efficacy and immunogenicity compared with the original unconjugated vaccine. They stimulate an immune response that is distinctly different from that elicited by the original vaccine. Two vaccine products are currently licensed for use in children as young as two months of age, thus conferring immunity to those children at highest risk for Hib disease. CONCLUSIONS: The new Hib conjugate vaccines provide excellent efficacy and, when used as recommended, may significantly reduce the incidence of invasive Hib disease and its sequelae.

scholarly journals Whole-Genome Sequence of Entomortierella parvispora E1425, a Mucoromycotan Fungus Associated with Burkholderiaceae -Related Endosymbiotic Bacteria

2022 ◽  
Author(s):  
Afri Herlambang ◽  
Yong Guo ◽  
Yusuke Takashima ◽  
Kazuhiko Narisawa ◽  
Hiroyuki Ohta ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Genomic Information ◽  
Content Type ◽  
Symbiotic Associations ◽  
Endosymbiotic Bacteria

Some mucoromycotan fungi establish symbiotic associations with endohyphal bacteria. Here, the genome of Entomortierella parvispora E1425 (synonymously known as Mortierella parvispora E1425), which harbors a cultured Burkholderiaceae -related endobacterium (BRE) designated Mycoavidus sp. Strain B2-EB, was sequenced. We provide genomic information to elucidate fungal-BRE symbiotic features.

scholarly journals Anti-Polyribosylribitol Phosphate Antibody Concentrations and Avidities in Children since the Start of Haemophilus influenzae Type b Immunization of Infants in the United Kingdom

2008 ◽  
Vol 16 (2) ◽  
pp. 246-252 ◽  
Author(s):  
Dominic F. Kelly ◽  
E. Richard Moxon ◽  
Ly-Mee Yu ◽  
Andrew J. Pollard
Keyword(s):  
United Kingdom ◽  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Haemophilus Influenzae Type ◽  
Antibody Concentration ◽  
Type B ◽  
Conjugate Vaccines ◽  
Factors Affecting ◽  
The United Kingdom ◽  
Polyribosylribitol Phosphate

ABSTRACT The introduction of routine infant immunization with Haemophilus influenzae type b (Hib) conjugate vaccines in the United Kingdom in 1992 led to a significant reduction in invasive disease due to this organism. Subsequently, between 1999 and 2003 there was an increase in the number of immunized children with Hib infection. We investigated whether the rise in cases was related to changes in anti-polyribosylribitol phosphate (PRP) antibody concentration or avidity. Using stored sera, we analyzed temporal changes in antibody levels among 3- to 5-year-old children immunized between 1991 and 2000. Anti-PRP antibody concentrations were higher in 3- to 5-year-olds who received infant immunization in 1991 than those in subsequent years. This difference may be related to changes in either the mode of administration of Hib conjugate vaccines or the rates of Hib nasopharyngeal carriage. This study emphasizes the factors affecting anti-PRP antibody concentration following immunization with conjugate vaccines and the importance of these in long-term protection from invasive disease.

scholarly journals Impact of Haemophilus influenzae type b conjugate vaccination on hospitalization for invasive disease in children fifteen years after its introduction in Italy

Vaccine ◽  
2017 ◽  
Vol 35 (46) ◽  
pp. 6297-6301 ◽  
Author(s):  
Domenico Martinelli ◽  
Chiara Azzari ◽  
Paolo Bonanni ◽  
Susanna Esposito ◽  
Elisabetta Franco ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Conjugate Vaccination

scholarly journals Complete Genome Sequence of the Arcobacter skirrowii Type Strain LMG 6621

2018 ◽  
Vol 7 (17) ◽  
Author(s):  
William G. Miller ◽  
Emma Yee
Keyword(s):  
Genome Sequence ◽  
Fecal Sample ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Type Strain ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Content Type ◽  
The United Kingdom ◽  
Veterinary Importance

Arcobacter skirrowii is a species of veterinary importance, originally recovered from the feces, aborted fetuses, and preputial fluids of livestock. We present here the whole-genome sequence of the A. skirrowii type strain LMG 6621 (= 449/80T = CCUG 10374T), isolated in the United Kingdom from a lamb diarrheal fecal sample.

scholarly journals Whole-Genome Sequence of Salmonella enterica subsp. enterica Serovar Typhimurium Strain UPM 260, Isolated from a Broiler Chicken in Perak, Malaysia

2017 ◽  
Vol 5 (46) ◽  
Author(s):  
Najwa Syahirah Roslan ◽  
Shagufta Jabeen ◽  
Nurulfiza Mat Isa ◽  
Abdul Rahman Omar ◽  
Mohd Hair Bejo ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Salmonella Enterica ◽  
Broiler Chicken ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Content Type ◽  
Typhimurium Strain ◽  
Serovar Typhimurium

ABSTRACT Salmonella enterica subsp. enterica serovar Typhimurium is one of several well-categorized Salmonella serotypes recognized globally. Here, we report the whole-genome sequence of S. Typhimurium strain UPM 260, isolated from a broiler chicken.

Epidemiology of Haemophilus Type B Invasive Disease in Childhood in Glasgow

1993 ◽  
Vol 38 (1) ◽  
pp. 18-20 ◽  
Author(s):  
A Coggins ◽  
C.W. Shepherd ◽  
F. Cockburn
Keyword(s):  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Annual Incidence ◽  
Childhood Vaccination ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Neurological Sequelae ◽  
The United Kingdom

The objective of this study was to investigate the epidemiology of invasive disease due to Haemophilus influenzae type b in childhood in Glasgow. A retrospective study has been made on the hospital records of 252 children aged 0 to 12 years admitted to Glasgow hospitals during 1981–1990. The annual incidence of invasive Haemophilus influenzae type b disease in Glasgow was estimated at 39 per 100,000 children less than five years of age per year. The figure for Haemophilus meningitis was 23.8 per 100,000 children less than five years of age per year. Ninety-five per cent of all cases occurred in children less than five years of age and 72.1% of meningitis cases occurred before two years of age. There was a mortality of 2.77%. Long-term neurological sequelae were found in 15.3% of the survivors. The annual incidence of Haemophilus influenzae type b disease is slightly higher in Glasgow than previously reported for the United Kingdom. The study provides baseline data to help assess efficacy of proposed early childhood vaccination.

scholarly journals Whole-Genome Sequence of Lactobacillus salivarius DJ-sa-01, Isolated from Chicken Small Intestine

2018 ◽  
Vol 7 (14) ◽  
Author(s):  
Dongjun Kim ◽  
Mun-Ju Cho ◽  
Seungchan Cho ◽  
Yongjun Lee ◽  
Sung June Byun ◽  
...  
Keyword(s):  
Small Intestine ◽  
Genome Sequence ◽  
Probiotic Strain ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Lactobacillus Salivarius ◽  
Circular Chromosome ◽  
Content Type ◽  
Single Circular Chromosome

We have identified the whole-genome sequence of Lactobacillus salivarius DJ-sa-01, a potential probiotic strain for poultry, isolated from a chicken small intestine. We used the PacBio and Illumina platforms to obtain the sequence of the entire single circular chromosome.

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