scholarly journals The Genome Sequence of Mycoplasma hyopneumoniae Strain 232, the Agent of Swine Mycoplasmosis

2004 ◽  
Vol 186 (21) ◽  
pp. 7123-7133 ◽  
Author(s):  
F. Chris Minion ◽  
Elliot J. Lefkowitz ◽  
Melissa L. Madsen ◽  
Barbara J. Cleary ◽  
Steven M. Swartzell ◽  
...  

ABSTRACT We present the complete genome sequence of Mycoplasma hyopneumoniae, an important member of the porcine respiratory disease complex. The genome is composed of 892,758 bp and has an average G+C content of 28.6 mol%. There are 692 predicted protein coding sequences, the average protein size is 388 amino acids, and the mean coding density is 91%. Functions have been assigned to 304 (44%) of the predicted protein coding sequences, while 261 (38%) of the proteins are conserved hypothetical proteins and 127 (18%) are unique hypothetical proteins. There is a single 16S-23S rRNA operon, and there are 30 tRNA coding sequences. The cilium adhesin gene has six paralogs in the genome, only one of which contains the cilium binding site. The companion gene, P102, also has six paralogs. Gene families constitute 26.3% of the total coding sequences, and the largest family is the 34-member ABC transporter family. Protein secretion occurs through a truncated pathway consisting of SecA, SecY, SecD, PrsA, DnaK, Tig, and LepA. Some highly conserved eubacterial proteins, such as GroEL and GroES, are notably absent. The DnaK-DnaJ-GrpR complex is intact, providing the only control over protein folding. There are several proteases that might serve as virulence factors, and there are 53 coding sequences with prokaryotic lipoprotein lipid attachment sites. Unlike other mycoplasmas, M. hyopneumoniae contains few genes with tandem repeat sequences that could be involved in phase switching or antigenic variation. Thus, it is not clear how M. hyopneumoniae evades the immune response and establishes a chronic infection.

Microbiology ◽  
2011 ◽  
Vol 157 (3) ◽  
pp. 760-773 ◽  
Author(s):  
Hagai Rechnitzer ◽  
Elzbieta Brzuszkiewicz ◽  
Axel Strittmatter ◽  
Heiko Liesegang ◽  
Inna Lysnyansky ◽  
...  

We present the complete genomic sequence of Mycoplasma fermentans, an organism suggested to be associated with the pathogenesis of rheumatoid arthritis in humans. The genome is composed of 977 524 bp and has a mean G+C content of 26.95 mol%. There are 835 predicted protein-coding sequences and a mean coding density of 87.6 %. Functions have been assigned to 58.8 % of the predicted protein-coding sequences, while 18.4 % of the proteins are conserved hypothetical proteins and 22.8 % are hypothetical proteins. In addition, there are two complete rRNA operons and 36 tRNA coding sequences. The largest gene families are the ABC transporter family (42 members), and the functionally heterogeneous group of lipoproteins (28 members), which encode the characteristic prokaryotic cysteine ‘lipobox’. Protein secretion occurs through a pathway consisting of SecA, SecD, SecE, SecG, SecY and YidC. Some highly conserved eubacterial proteins, such as GroEL and GroES, are notably absent. The genes encoding DnaK-DnaJ-GrpE and Tig, forming the putative complex of chaperones, are intact, providing the only known control over protein folding. Eighteen nucleases and 17 proteases and peptidases were detected as well as three genes for the thioredoxin-thioreductase system. Overall, this study presents insights into the physiology of M. fermentans, and provides several examples of the genetic basis of systems that might function as virulence factors in this organism.


2019 ◽  
Vol 8 (23) ◽  
Author(s):  
Si Chul Kim ◽  
Hyo Jung Lee

Here, we report the draft genome sequence of Pseudorhodobacter sp. strain E13, a Gram-negative, aerobic, nonflagellated, and rod-shaped bacterium which was isolated from the Yellow Sea in South Korea. The assembled genome sequence is 3,878,578 bp long with 3,646 protein-coding sequences in 159 contigs.


2016 ◽  
Vol 4 (6) ◽  
Author(s):  
Xuehua Wan ◽  
Shaobin Hou ◽  
Kazukuni Hayashi ◽  
James Anderson ◽  
Stuart P. Donachie

Rheinheimera salexigens KH87 T is an obligately halophilic gammaproteobacterium. The strain’s draft genome sequence, generated by the Roche 454 GS FLX+ platform, comprises two scaffolds of ~3.4 Mbp and ~3 kbp, with 3,030 protein-coding sequences and 58 tRNA coding regions. The G+C content is 42 mol%.


2019 ◽  
Vol 8 (43) ◽  
Author(s):  
Zothanpuia ◽  
Ajit Kumar Passari ◽  
Purbajyoti Deka ◽  
Vinay Rajput ◽  
Lakshmi P. M. Priya ◽  
...  

We report the draft genome sequence of Streptomyces sp. strain BPSDS2, isolated from freshwater sediments in Northeast India. The draft genome has a size of 8.27 Mb and 7,559 protein-coding sequences.


2017 ◽  
Vol 5 (16) ◽  
Author(s):  
Kazunori Yamamoto ◽  
Yasuhisa Asano

ABSTRACT We report here the genome sequence of Microbacterium sp. strain TPU 3598, previously described as a producer of lumichrome. The sequenced genome size is 3,787,270 bp, the average G+C content is 68.39%, and 3,674 protein-coding sequences are predicted.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Yunci Qi ◽  
John M. D’Alessandro ◽  
Joshua A. V. Blodgett

ABSTRACT Here, we report the draft genome sequence of Streptomyces sp. JV178, a strain originating from Connecticut (USA) garden soil. This strain produces the polycyclic tetramate macrolactam compounds clifednamides A and B. The draft genome contains 10.65 Mb, 9,045 predicted protein coding sequences, and several natural product biosynthetic loci.


2020 ◽  
Vol 9 (36) ◽  
Author(s):  
Ken Ishioka ◽  
Kyoko Nishiyama ◽  
Tatsuo Suzutani

ABSTRACT We report here the draft genome sequence of Lactococcus lactis strain 11/19-B1, isolated from kiwifruit. The 11/19-B1 strain possesses one chromosome and five plasmids and has a predicted 2,429 protein-coding sequences. DFAST annotation and a BLASTp homology search estimated that 11/19-B1 possesses three bacteriocin immunity proteins and four bacteriocin proteins.


2016 ◽  
Vol 4 (4) ◽  
Author(s):  
Jhasketan Badhai ◽  
Kunwar Digvijay Narayan ◽  
William B. Whitman ◽  
Subrata K. Das

Gulbenkiania indica strain HT27 T was isolated from a sulfur spring. Here, we report the first representative draft genome sequence of a type strain of the genus Gulbenkiania . The estimated genome is 2.8 Mb, with 2,713 protein-coding sequences.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Anna-Kathrin Schuster ◽  
Ulrich Szewzyk

Rheinheimera sp. strain F8 is a biofilm-forming gammaproteobacterium that has been found to produce large amounts of filamentous extracellular DNA. Here, we announce the de novo assembly of its genome. It is estimated to be 4,464,511 bp in length, with 3,970 protein-coding sequences and 92 RNA-coding sequences.


2017 ◽  
Vol 5 (18) ◽  
Author(s):  
Saumya Bandyopadhyay ◽  
William B. Whitman ◽  
Subrata K. Das

ABSTRACT Pannonibacter indicus strain HT23T, a highly arsenate-tolerant bacterium, was isolated from a tropical hot spring. The estimated genome is 4.2 Mb with 3,818 protein-coding sequences containing putative genes, some of which are involved in arsenate resistance.


Sign in / Sign up

Export Citation Format

Share Document