First Report of Human Infection with Salmonella enterica Serovar Apapa Resulting from Exposure to a Pet Lizard

Salmonella enterica serovar Enteritidis (SE) is a major foodborne pathogen primarily causing human infection through contaminated chicken eggs. To understand how SE survives in chicken egg albumen, we systematically and quantitatively analysed the survival properties of SE in egg albumen and identified factors affecting its survival. Survival assays of SE in egg indicate that egg albumen restricted the growth of SE. A major factor that controlled SE's growth in egg albumen was iron restriction, since egg albumen supplemented with iron allowed SE to grow, and iron acquisition mutants of SE showed decreased survival in egg albumen. In addition, low pH of albumen, high concentrations of bacteria and low incubation temperatures of bacteria with albumen facilitates the survival of SE. Our results suggest that egg albumen uses multiple mechanisms to control SE including iron limitation, surface interaction and possible enzymatic activities.

Download Full-text

First report of mcr-1-harboring Salmonella enterica serovar Schwarzengrund isolated from poultry meat in Brazil

Diagnostic Microbiology and Infectious Disease ◽

10.1016/j.diagmicrobio.2018.10.016 ◽

2019 ◽

Vol 93 (4) ◽

pp. 376-379 ◽

Cited By ~ 11

Author(s):

Luisa Z. Moreno ◽

Vasco T.M. Gomes ◽

Jéssica Moreira ◽

Carolina H. de Oliveira ◽

Bárbara P. Peres ◽

...

Keyword(s):

Salmonella Enterica ◽

Poultry Meat ◽

First Report

Download Full-text

Genotypic characterization of antibiotic-resistant Salmonella Enteritidis isolates in Dakar, Senegal

The Journal of Infection in Developing Countries ◽

10.3855/jidc.365 ◽

2007 ◽

Vol 1 (03) ◽

pp. 284-288 ◽

Cited By ~ 9

Author(s):

Amy Gassama Sow ◽

Abdoul Aziz Wane ◽

Mamadou Hadi Diallo ◽

Cheikh Saad-Bouh Boye ◽

Awa Aïdara-Kane

Keyword(s):

Antibiotic Resistance ◽

Antimicrobial Resistance ◽

Salmonella Enterica ◽

Salmonella Enteritidis ◽

Data Bank ◽

Human Infection ◽

Molecular Techniques ◽

Conjugative Plasmid ◽

Bacterial Strains ◽

Salmonella Enterica Serovar Enteritidis

Background: It is well established that Salmonella enterica is a major cause of food-borne disease worldwide. In Africa, according to the Who Global Salm-Surv country data bank from 2000 to 2002 Salmonella enterica serovar Enteritidis was the most common serotype involved in human salmonellosis. In Dakar this serotype of Salmonella has been reported as a frequent and an increasing cause of human infection. Methodology: The genetic determinants of the antimicrobial resistance of 25 selected multiresistant strains of Salmonella enterica serovar Enteritidis referred to the National Reference Center for Enterobacteria (NRCE) in Dakar were investigated using molecular techniques. Results: All strains carried blaTEM 1 genes. Five harboured three types of class 1 integrons with gene cassettes dfrA15, dfrA1-aadA1 and dfrA7. Multiresistance was due to a 23 Kb conjugative plasmid. DNA fingerprinting by macrorestriction of genomic DNA revealed a single related group suggesting that strains might be clonal. Conclusions: The spread of resistance genes through plasmid transfer plays an important role in the dissemination of antibiotic resistance in enteric pathogens such as Salmonella Enteritidis; the risk of transmissibility of antibiotic resistance between different bacterial strains highlights the urgent need to develop strategies to limit the spread of antimicrobial resistance among bacterial enteropathogens.

Download Full-text